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BioActivity Data for Compound cumene hydroperoxide (CID 6629)

BioActivity Outcomes:
Active(35)
 
 
Inactive(275)
 
 
Inconclusive(152)
 
 
Unspecified(10)
 
 
Top Targets:
NR LBD PPAR(18)
 
 
 
NR LBD TR(11)
 
 
 
NR LBD ER(11)
 
 
 
NR LBD AR(11)
 
 
 
NR LBD VDR(8)
 
 
 
BioAssay Types:
Confirmatory(253)
 
 
 
 
Summary(29)
 
 
 
 
Literature(4)
 
 
 
BioAssay Categories:
In vitro(1)
 
 
Toxicity(46)
 
 
 
 
 
ADME(6)
 
 
Cell-based(1)
 
 
BioActivity Types:
Potency(240)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 258    Data Row: 472   Total Pages: 24   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID17389088]
Potency 0.1259qHTS Assay for Inhibitors of 15-hLO (15-human lipoxygenase) [AID887, Type: confirmatory]15-lipoxygenase, partial [Homo sapiens] [gi:1832253]
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2
[SID26753098]
Potency 12.5893qHTS assay for small molecule agonists of estrogen receptor alpha signaling [AID588514, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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3
[SID144210603]
Potency-Replicate_1 17.2289qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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4
[SID17389088]
Potency 25.1189Cell Viability - LYMP2-010 [AID981, Type: confirmatory]
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5
[SID144210603]
Potency-Replicate_1 27.306qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
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6
[SID144210603]
Potency-Replicate_1 30.6379qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
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7
[SID17389088]
Potency 31.6228Cell Viability - LYMP2-007 [AID979, Type: confirmatory]
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8
[SID17389088]
Potency 31.6228Cell Viability - LYMP2-024 [AID988, Type: confirmatory]
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9
[SID17389088]
Potency 39.8107Cell Viability - LYMP2-008 [AID980, Type: confirmatory]
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10
[SID17389088]
Potency 39.8107Cell Viability - LYMP2-015 [AID971, Type: confirmatory]
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11
[SID17389088]
Potency 39.8107Cell Viability - LYMP2-001 [AID921, Type: confirmatory]
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12
[SID17389088]
Potency 39.8107Cell Viability - LYMP2-005 [AID967, Type: confirmatory]
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13
[SID17389088]
Potency 39.8107Cell Viability - LYMP2-022 [AID987, Type: confirmatory]
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14
[SID17389088]
Potency 42.1632qHTS assay for small molecule antagonists of the retinoid-related orphan receptor gamma (ROR-gamma) signaling pathway [AID651802, Type: confirmatory]Nuclear receptor ROR-gamma [gi:49066040]
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15
[SID144210603]
Potency-Replicate_1 43.6412qHTS assay to identify small molecule agonists of the endoplasmic reticulum stress response signaling pathway - cell viability counter screen [AID1159517, Type: confirmatory]
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16
[SID144210603]
Potency-Replicate_1 48.9662qHTS assay for small molecule activators of the heat shock response signaling pathway - cell viability counter screen [AID743209, Type: confirmatory]
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17
[SID17389088]
Potency 50.1187Cell Viability - LYMP2-003 [AID965, Type: confirmatory]
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18
[SID17389088]
Potency 50.1187Cell Viability - LYMP2-017 [AID972, Type: confirmatory]
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19
[SID17389088]
Potency 50.1187Cell Viability - LYMP2-021 [AID974, Type: confirmatory]
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20
[SID144210603]
Potency-Replicate_1 54.941qHTS assay to identify small molecule agonists of the vitamin D receptor (VDR) signaling pathway - cell viability counter screen [AID743224, Type: confirmatory]
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