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BioActivity Data for Compound bisphenol A (CID 6623)

BioActivity Outcomes:
Active(76)
 
 
Inactive(943)
 
 
Inconclusive(102)
 
 
Unspecified(581)
 
 
Top Targets:
7tm 4(70)
 
 
 
NR LBD PPAR(31)
 
 
 
 
NR LBD ER(29)
 
 
 
 
 
NR LBD AR(22)
 
 
 
 
NR LBD TR(18)
 
 
 
 
BioAssay Types:
Confirmatory(738)
 
 
 
 
 
Screening(373)
 
 
 
Summary(48)
 
 
 
 
Literature(43)
 
 
 
 
 
BioActivity Types:
Potency(544)
 
 
 
 
 
IC50(154)
 
 
 
 
Kd(7)
 
 
 
EC50(5)
 
 
 
AC50(3)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 1332    Data Row: 1702   Total Pages: 86   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103308477]
Kd 0.0055Binding affinity to human ERR gamma [AID1121409, Type: confirmatory]Estrogen-related receptor gamma [gi:50402102]
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2
[SID87557090]
Kd 0.0055Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain A, Crystal Structure Of Human Estrogen-Related Receptor Gamma Ligand Binding Domain Complex With Bisphenol A [gi:158428232]
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3
[SID87557090]
Kd 0.0055Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain A, Crystal Structure Of Human Estrogen-Related Receptor Gamma Ligand Binding Domain Complex With Bisphenol A [gi:158428232]
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4
[SID144214049]
Potency-Replicate_1 0.2207qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line [AID743079, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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5
[SID87557175]
Kd 0.297Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain A, X-Ray Structure Of Estrogen Related Receptor G In Complex With Bisphenol A. [gi:168988660]
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6
[SID87557175]
Kd 0.297Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain A, X-Ray Structure Of Estrogen Related Receptor G In Complex With Bisphenol A. [gi:168988660]
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7
[SID144214049]
Potency-Replicate_1 0.4443qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway [AID743075, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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8
[SID144210190]
Potency-Replicate_1 0.4802qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line [AID743079, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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9
[SID103308477]
EC50 1.1Agonist activity at human Gal4-ERbeta by reporter gene assay [AID758901, Type: Literature]Estrogen receptor beta [gi:6166154]
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10
[SID144210190]
Ratio Potency (uM) 1.12685qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway: Summary [AID743077, Type: summary]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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11
[SID103308477]
IC50 1.304DRUGMATRIX: Lipoxygenase 15-LO enzyme inhibition (substrate: Linoleic acid) [AID625146, Type: confirmatory]Arachidonate 15-lipoxygenase [gi:126397]
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12
[SID144214049]
Ratio Potency (uM) 1.50646qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway: Summary [AID743077, Type: summary]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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13
[SID144210190]
Potency-Replicate_1 1.9272qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway [AID743075, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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14
[SID103308477]
IC50 2.271DRUGMATRIX: Estrogen ERalpha radioligand binding (ligand: [3H] Estradiol) [AID625258, Type: confirmatory]Estrogen receptor [gi:544257]
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15
[SID103308477]
IC50 5.42DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT6 radioligand binding (ligand: [3H] Lysergic acid diethylamide) [AID625221, Type: confirmatory]5-hydroxytryptamine receptor 6 [gi:1703010]
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16
[SID144214049]
Potency-Replicate_1 5.5426qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
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17
[SID103308477]
IC50 5.9Antagonist activity at human pSG5-AR assessed as inhibition of dihydrotestosterone-induced effect by reporter gene assay [AID758894, Type: Literature]Androgen receptor [gi:113830]
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18
[SID144210190]
Potency-Replicate_1 6.7823qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
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19
[SID144214049]
Potency-Replicate_1 8.7076qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway [AID743069, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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20
[SID92277586]
Secondary IC50 9.3Identification of SV40 T antigen inhibitors: A Secondary Screen for the Cytotoxicity and Efficacy using BSC cells (3) [AID485276, Type: confirmatory]
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