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ChemDiv2_007673 (CID 6620376) - Compound BioActivity Data
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BioActivity Outcomes:
Active(6)
 
 
Inactive(6)
 
 
Top Targets:
G6PD N(6)
 
 
G6PD C(2)
 
 
DUF3346(1)
 
 
G glu transpe..(1)
 
 
DnaB C(1)
 
 
BioAssay Types:
Confirmatory(8)
 
 
 
BioActivity Types:
IC50(8)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 10    Data Row: 12   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID125264922]
IC50_Mean 6.42SAR analysis of small molecule inhibitors of Plasmodium falciparum Glucose-6-phosphate dehydrogenase in an orthogonal kinetic assay utilizing the direct detection of NADPH [AID588593, Type: confirmatory]glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase [Plasmodium berghei] [gi:12381848]
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2
[SID124756823]
IC50_Mean 6.64SAR analysis of small molecule inhibitors of Plasmodium falciparum Glucose-6-phosphate dehydrogenase in an orthogonal assay utilizing the direct end-point detection of NADPH [AID588588, Type: confirmatory]glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase [Plasmodium berghei] [gi:12381848]
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3
[SID124756823]
IC50_Mean 8.01SAR analysis of small molecule inhibitors of Plasmodium falciparum Glucose-6-phosphate dehydrogenase in an orthogonal kinetic assay utilizing the direct detection of NADPH [AID588593, Type: confirmatory]glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase [Plasmodium berghei] [gi:12381848]
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4
[SID125264922]
IC50_Mean 9.89SAR analysis of small molecule inhibitors of Plasmodium falciparum Glucose-6-phosphate dehydrogenase in an orthogonal assay utilizing the direct end-point detection of NADPH [AID588588, Type: confirmatory]glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase [Plasmodium berghei] [gi:12381848]
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5
[SID125264922]
IC50_Mean 9.89SAR analysis of small molecule inhibitors of Plasmodium falciparum Glucose-6-phosphate dehydrogenase via a fluorescence intensity assay - Set 2 [AID588671, Type: confirmatory]glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase [Plasmodium berghei] [gi:12381848]
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6
[SID124756823]
IC50_Mean 12.2SAR analysis of small molecule inhibitors of Plasmodium falciparum Glucose-6-phosphate dehydrogenase via a fluorescence intensity assay [AID588415, Type: confirmatory]glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase [Plasmodium berghei] [gi:12381848]
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7
[SID124756823]
IC50_Mean 80SAR analysis of small molecule inhibitors of Plasmodium falciparum Glucose-6-Phosphate Dehydrogenase using a Human Glucose-6-Phosphate Dehydrogenase Dose Response Selectivity Assay [AID588414, Type: confirmatory]glucose-6-phosphate 1-dehydrogenase isoform b [Homo sapiens] [gi:108773793]
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8
[SID125264922]
IC50_Mean 80SAR analysis of small molecule inhibitors of Plasmodium falciparum Glucose-6-Phosphate Dehydrogenase using a Human Glucose-6-Phosphate Dehydrogenase Dose Response Selectivity Assay - Set 2 [AID588672, Type: confirmatory]glucose-6-phosphate 1-dehydrogenase isoform b [Homo sapiens] [gi:108773793]
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9
[SID92243691]
A screen for compounds that inhibit the CapD enzyme of Bacillus anthracis [AID492967, Type: other]gamma-glutamyltranspeptidase [Bacillus anthracis str. 'Ames Ancestor'] [gi:47566732]
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10
[SID92243691]
A screen for compounds that inhibit replication of Vibrio cholerae chromosome II [AID504770, Type: other]hypothetical protein VC_A0002 [Vibrio cholerae O1 biovar El Tor str. N16961] [gi:9657380]
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11
[SID92243691]
A screen for compounds that inhibit the activity of Staphylococcus aureus DNA helicase [AID485395, Type: other]replicative DNA helicase [Staphylococcus aureus subsp. aureus JH1] [gi:150392496]
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12
[SID92243691]
A screen for compounds that inhibit the activity of LtaS in Staphylococcus aureus [AID720641, Type: other]anion-binding protein [Staphylococcus aureus subsp. aureus Mu50] [gi:15923709]
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