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SMR000034463 (CID 661788) - Compound BioActivity Data
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BioActivity Outcomes:
Active(30)
 
 
Inactive(848)
 
 
Inconclusive(38)
 
 
Unspecified(2)
 
 
Top Targets:
7tm 4(54)
 
 
 
TRP 2(20)
 
 
 
alkPPc(16)
 
 
Bcl-2 like(12)
 
 
Tryp SPc(11)
 
 
BioAssay Types:
Screening(584)
 
 
 
 
Confirmatory(301)
 
 
 
 
 
Literature(11)
 
 
Summary(1)
 
 
BioActivity Types:
Potency(206)
 
 
 
 
 
IC50(52)
 
 
EC50(20)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 811    Data Row: 918   Total Pages: 46   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID26670736]
EC50 0.01406Luminescence-based cell-based high throughput dose response assay for agonists of heterodimerization of the mu 1 (OPRM1) and delta 1 (OPRD1) opioid receptors [AID588407, Type: confirmatory]mu-type opioid receptor isoform MOR-1 [Homo sapiens] [gi:117940060]
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2
[SID26670736]
EC50 0.01406Luminescence-based cell-based high throughput dose response assay for agonists of heterodimerization of the mu 1 (OPRM1) and delta 1 (OPRD1) opioid receptors [AID588407, Type: confirmatory]delta-type opioid receptor [Homo sapiens] [gi:63477962]
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3
[SID26670736]
EC50 0.01731Counterscreen for agonists of heterodimerization of the mu 1 (OPRM1) and delta 1 (OPRD1) opioid receptors: Luminescence-based cell-based high throughput dose response assay to identify agonists of OPRD1 homodimerization [AID588411, Type: confirmatory]delta-type opioid receptor [Homo sapiens] [gi:63477962]
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4
[SID860502]
EC50 0.1493Confirmation dose response assay for compounds that activate transient receptor potential cation channel C4 (TRPC4) [AID434937, Type: confirmatory]alternatively spliced Trp4 [Mus musculus] [gi:2935630]
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5
[SID860502]
Potency 0.631qHTS Assay for Agonists of the Thyroid Stimulating Hormone Receptor [AID926, Type: confirmatory]thyroid stimulating hormone receptor [Homo sapiens] [gi:38016895]
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6
[SID860502]
Potency 0.631Confirmation Concentration-Response Assay for Agonists of the Thyroid Stimulating Hormone Receptor [AID939, Type: confirmatory]thyroid stimulating hormone receptor [Homo sapiens] [gi:38016895]
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7
[SID860502]
Potency 10.4179Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation [AID504834, Type: confirmatory]
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8
[SID124888752]
Potency 11.2202qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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9
[SID860502]
Potency 12.5893qHTS Assay for Inhibitors of Influenza NS1 Protein Function [AID2326, Type: confirmatory]nonstructural protein 1 [Influenza A virus (A/WSN/1933(H1N1))] [gi:194352380]
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10
[SID57655021]
Potency 15.8489Secondary Concentration-Response Assay for Agonists of the Thyroid Stimulating Hormone Receptor: HTRF Activity Detection [AID933, Type: confirmatory]thyroid stimulating hormone receptor [Homo sapiens] [gi:38016895]
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11
[SID860502]
Potency 15.8489qHTS Assay for Inhibitors of 15-hLO (15-human lipoxygenase) [AID887, Type: confirmatory]15-lipoxygenase, partial [Homo sapiens] [gi:1832253]
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12
[SID860502]
Potency 31.6228qHTS Assay for Inhibitors of HSD17B4, hydroxysteroid (17-beta) dehydrogenase 4 [AID893, Type: confirmatory]Chain A, The Structure Of Wild-Type Human Hadh2 (17beta-Hydroxysteroid Dehydrogenase Type 10) Bound To Nad+ At 1.2 A [gi:122921310]
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13
[SID860502]
Potency 31.6228qHTS Assay for Inhibitors of HSD17B4, hydroxysteroid (17-beta) dehydrogenase 4 [AID893, Type: confirmatory]Chain B, The Structure Of Wild-Type Human Hadh2 (17beta-Hydroxysteroid Dehydrogenase Type 10) Bound To Nad+ At 1.2 A [gi:122921311]
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14
[SID26670736]
Potency 31.6228qHTS Assay for Activators of ClpP [AID651965, Type: confirmatory]ClpP [Bacillus subtilis] [gi:2668494]
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15
[SID57655021]
Potency 89.1251qHTS Assay for Inhibitors of JMJD2A-Tudor Domain [AID504339, Type: confirmatory]Chain A, Jmjd2a Tandem Tudor Domains In Complex With A Trimethylated Histone H4-K20 Peptide [gi:162330054]
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16
[SID860502]
CYP2C9 Assay [AID777, Type: screening]cytochrome P450 2C9 precursor [Homo sapiens] [gi:13699818]
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17
[SID57655021]
Quantitative High-Throughput Screen for Agonists of Thyroid Stimulating Hormone Receptor: Summary [AID1401, Type: summary]thyroid stimulating hormone receptor [Homo sapiens] [gi:38016895]
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18
[SID860502]
CYP2C19 Assay [AID778, Type: screening]cytochrome P450 2C19 precursor [Homo sapiens] [gi:4503219]
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19
[SID860502]
Specificity screen against TRPC6 for compounds that activate transient receptor potential cation channel C4 (TRPC4) [AID434950, Type: screening]short transient receptor potential channel 6 isoform 1 [Mus musculus] [gi:160333370]
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20
[SID26670736]
Luminescence-based cell-based high throughput confirmation assay for agonists of heterodimerization of the mu 1 (OPRM1) and delta 1 (OPRD1) opioid receptors [AID504904, Type: screening]mu-type opioid receptor isoform MOR-1 [Homo sapiens] [gi:117940060]
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