SMR000034463 (CID 661788) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(26)
 
 
Inactive(745)
 
 
Inconclusive(36)
 
 
Unspecified(2)
 
 
Top Targets:
7TM GPCR Srx(22)
 
 
TRP 2(20)
 
 
 
alkPPc(16)
 
 
Bcl-2 like(11)
 
 
7TM GPCR Srsx(10)
 
 
BioAssay Types:
Screening(515)
 
 
 
 
Confirmatory(268)
 
 
 
 
 
Literature(5)
 
 
Summary(1)
 
 
BioActivity Types:
Potency(181)
 
 
 
 
 
IC50(47)
 
 
EC50(19)
 
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 780    Data Row: 809   Total Pages: 17   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID26670736]
EC50 0.01406Luminescence-based cell-based high throughput dose response assay for agonists of heterodimerization of the mu 1 (OPRM1) and delta 1 (OPRD1) opioid receptors [AID588407, Type: confirmatory]OPRD1 gene product [Homo sapiens] [gi:63477962]
View
2
[SID26670736]
EC50 0.01406Luminescence-based cell-based high throughput dose response assay for agonists of heterodimerization of the mu 1 (OPRM1) and delta 1 (OPRD1) opioid receptors [AID588407, Type: confirmatory]OPRD1 gene product [Homo sapiens] [gi:63477962]
View
3
[SID26670736]
EC50 0.01731Counterscreen for agonists of heterodimerization of the mu 1 (OPRM1) and delta 1 (OPRD1) opioid receptors: Luminescence-based cell-based high throughput dose response assay to identify agonists of OPRD1 homodimerization [AID588411, Type: confirmatory]OPRD1 gene product [Homo sapiens] [gi:63477962]
View
4
[SID26670736]
EC50 0.01731Counterscreen for agonists of heterodimerization of the mu 1 (OPRM1) and delta 1 (OPRD1) opioid receptors: Luminescence-based cell-based high throughput dose response assay to identify agonists of OPRD1 homodimerization [AID588411, Type: confirmatory]OPRD1 gene product [Homo sapiens] [gi:63477962]
View
5
[SID860502]
EC50 0.1493Confirmation dose response assay for compounds that activate transient receptor potential cation channel C4 (TRPC4) [AID434937, Type: confirmatory]alternatively spliced Trp4 [Mus musculus] [gi:2935630]
View
6
[SID860502]
Potency 0.631qHTS Assay for Agonists of the Thyroid Stimulating Hormone Receptor [AID926, Type: confirmatory]thyroid stimulating hormone receptor [Homo sapiens] [gi:38016895]
View
7
[SID860502]
Potency 0.631qHTS Assay for Agonists of the Thyroid Stimulating Hormone Receptor [AID926, Type: confirmatory]thyroid stimulating hormone receptor [Homo sapiens] [gi:38016895]
View
8
[SID860502]
Potency 0.631qHTS Assay for Agonists of the Thyroid Stimulating Hormone Receptor [AID926, Type: confirmatory]thyroid stimulating hormone receptor [Homo sapiens] [gi:38016895]
View
9
[SID860502]
Potency 0.631Confirmation Concentration-Response Assay for Agonists of the Thyroid Stimulating Hormone Receptor [AID939, Type: confirmatory]thyroid stimulating hormone receptor [Homo sapiens] [gi:38016895]
View
10
[SID860502]
Potency 0.631Confirmation Concentration-Response Assay for Agonists of the Thyroid Stimulating Hormone Receptor [AID939, Type: confirmatory]thyroid stimulating hormone receptor [Homo sapiens] [gi:38016895]
View
11
[SID860502]
Potency 0.631Confirmation Concentration-Response Assay for Agonists of the Thyroid Stimulating Hormone Receptor [AID939, Type: confirmatory]thyroid stimulating hormone receptor [Homo sapiens] [gi:38016895]
View
12
[SID860502]
Potency 10.4179Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation [AID504834, Type: confirmatory]
View
13
[SID124888752]
Potency 11.2202qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
View
14
[SID124888752]
Potency 11.2202qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
View
15
[SID124888752]
Potency 11.2202qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
View
16
[SID860502]
Potency 12.5893qHTS Assay for Inhibitors of Influenza NS1 Protein Function [AID2326, Type: confirmatory]nonstructural protein 1 [Influenza A virus (A/WSN/1933(H1N1))] [gi:194352380]
View
17
[SID860502]
Potency 15.8489qHTS Assay for Inhibitors of 15-hLO (15-human lipoxygenase) [AID887, Type: confirmatory]15-lipoxygenase [Homo sapiens] [gi:1832253]
View
18
[SID860502]
Potency 15.8489qHTS Assay for Inhibitors of 15-hLO (15-human lipoxygenase) [AID887, Type: confirmatory]15-lipoxygenase [Homo sapiens] [gi:1832253]
View
19
[SID57655021]
Potency 15.8489Secondary Concentration-Response Assay for Agonists of the Thyroid Stimulating Hormone Receptor: HTRF Activity Detection [AID933, Type: confirmatory]thyroid stimulating hormone receptor [Homo sapiens] [gi:38016895]
View
20
[SID57655021]
Potency 15.8489Secondary Concentration-Response Assay for Agonists of the Thyroid Stimulating Hormone Receptor: HTRF Activity Detection [AID933, Type: confirmatory]thyroid stimulating hormone receptor [Homo sapiens] [gi:38016895]
View
21
[SID57655021]
Potency 15.8489Secondary Concentration-Response Assay for Agonists of the Thyroid Stimulating Hormone Receptor: HTRF Activity Detection [AID933, Type: confirmatory]thyroid stimulating hormone receptor [Homo sapiens] [gi:38016895]
View
22
[SID26670736]
Potency 31.6228qHTS Assay for Activators of ClpP [AID651965, Type: confirmatory]ClpP [Bacillus subtilis] [gi:2668494]
View
23
[SID860502]
Potency 31.6228qHTS Assay for Inhibitors of HSD17B4, hydroxysteroid (17-beta) dehydrogenase 4 [AID893, Type: confirmatory]Chain A, The Structure Of Wild-Type Human Hadh2 (17beta- Hydroxysteroid Dehydrogenase Type 10) Bound [gi:122921310]
View
24
[SID57655021]
Potency 89.1251qHTS Assay for Inhibitors of JMJD2A-Tudor Domain [AID504339, Type: confirmatory]Chain A, Jmjd2a Tandem Tudor Domains In Complex With A Trimethylated Histone H4-K20 Peptide [gi:162330054]
View
25
[SID860502]
 CYP2C19 Assay [AID778, Type: screening]cytochrome P450, family 2, subfamily C, polypeptide 19 [Homo sapiens] [gi:4503219]
View
26
[SID860502]
 CYP2C19 Assay [AID778, Type: screening]cytochrome P450, family 2, subfamily C, polypeptide 19 [Homo sapiens] [gi:4503219]
View
27
[SID860502]
 CYP2C9 Assay [AID777, Type: screening]cytochrome P450, family 2, subfamily C, polypeptide 9 [Homo sapiens] [gi:13699818]
View
28
[SID860502]
 CYP2C9 Assay [AID777, Type: screening]cytochrome P450, family 2, subfamily C, polypeptide 9 [Homo sapiens] [gi:13699818]
View
29
[SID860502]
 CYP2C9 Assay [AID777, Type: screening]cytochrome P450, family 2, subfamily C, polypeptide 9 [Homo sapiens] [gi:13699818]
View
30
[SID860502]
 Heat Shock Factor-1 (HSF-1) Measured in Cell-Based System Using Plate Reader - 2038-01_Activator_SinglePoint_HTS_Activity [AID504408, Type: screening]
View
31
[SID26670736]
 HTS to Find Inhibitors of Pathogenic Pemphigus Antibodies [AID588358, Type: screening]
View
32
[SID860502]
 Profiling the NIH Molecular Libraries Small Molecule Repository: Autofluorescence at 339/460 nm [AID709, Type: screening]
View
33
[SID860502]
 qHTS Assay for Spectroscopic Profiling in 4-MU Spectral Region [AID589, Type: other]
View
34
[SID860502]
 qHTS Assay for Spectroscopic Profiling in A350 Spectral Region [AID590, Type: other]
View
35
[SID57655021]
 Quantitative High-Throughput Screen for Agonists of Thyroid Stimulating Hormone Receptor: Summary [AID1401, Type: summary]thyroid stimulating hormone receptor [Homo sapiens] [gi:38016895]
View
36
[SID57655021]
 Quantitative High-Throughput Screen for Agonists of Thyroid Stimulating Hormone Receptor: Summary [AID1401, Type: summary]thyroid stimulating hormone receptor [Homo sapiens] [gi:38016895]
View
37
[SID57655021]
 Quantitative High-Throughput Screen for Agonists of Thyroid Stimulating Hormone Receptor: Summary [AID1401, Type: summary]thyroid stimulating hormone receptor [Homo sapiens] [gi:38016895]
View
38
[SID860502]
 Specificity screen against TRPC6 for compounds that activate transient receptor potential cation channel C4 (TRPC4) [AID434950, Type: screening]short transient receptor potential channel 6 [Mus musculus] [gi:160333370]
View
39
[SID860502]
 Primary cell-based screen for identification of compounds that activate transient receptor potential cation channel C4 (TRPC4). [AID2237, Type: screening]alternatively spliced Trp4 [Mus musculus] [gi:2935630]
View
40
[SID26670736]
 Fluorescence-based biochemical primary high throughput screening assay to identify inhibitors of the fructose-bisphosphate aldolase (FBA) of M. tuberculosis [AID588726, Type: screening]Probable fructose-bisphosphate aldolase Fba [Mycobacterium tuberculosis H37Rv] [gi:15607504]
View
41
[SID26670736]
 Luminescence-based cell-based primary high throughput screening assay to identify agonists of heterodimerization of the mu 1 (OPRM1) and delta 1 (OPRD1) opioid receptors [AID504326, Type: screening]OPRD1 gene product [Homo sapiens] [gi:63477962]
View
42
[SID26670736]
 Luminescence-based cell-based primary high throughput screening assay to identify agonists of heterodimerization of the mu 1 (OPRM1) and delta 1 (OPRD1) opioid receptors [AID504326, Type: screening]OPRD1 gene product [Homo sapiens] [gi:63477962]
View
43
[SID26670736]
 Luminescence-based cell-based high throughput confirmation assay for agonists of heterodimerization of the mu 1 (OPRM1) and delta 1 (OPRD1) opioid receptors [AID504904, Type: screening]OPRD1 gene product [Homo sapiens] [gi:63477962]
View
44
[SID26670736]
 Luminescence-based cell-based high throughput confirmation assay for agonists of heterodimerization of the mu 1 (OPRM1) and delta 1 (OPRD1) opioid receptors [AID504904, Type: screening]OPRD1 gene product [Homo sapiens] [gi:63477962]
View
45
[SID124888752]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
View
46
[SID124888752]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
View
47
[SID26670736]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
View
48
[SID26670736]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
View
49
[SID860502]
Potency 1.5849qHTS Assay for Inhibitors of Ubiquitin-specific Protease USP2a [AID927, Type: confirmatory]ubiquitin carboxyl-terminal hydrolase 2 isoform a [Homo sapiens] [gi:188528692]
View
50
[SID860502]
Potency 1.5849qHTS Assay for Inhibitors of Ubiquitin-specific Protease USP2a [AID927, Type: confirmatory]ubiquitin carboxyl-terminal hydrolase 2 isoform a [Homo sapiens] [gi:188528692]
View