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CHEMBL431998 (CID 6604828) - Compound BioActivity Data
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BioActivity Outcomes:
Active(2)
 
 
Inactive(89)
 
 
Inconclusive(5)
 
 
Unspecified(4)
 
 
Top Targets:
p450(9)
 
 
 
 
HSD10-like SD..(4)
 
 
PLDc mTdp1 2(3)
 
 
Tubulin-bindi..(3)
 
 
 
IMPase(2)
 
 
BioAssay Types:
Confirmatory(89)
 
 
 
 
Literature(4)
 
 
 
Screening(1)
 
 
BioActivity Types:
Potency(69)
 
 
 
IC50(4)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 90    Data Row: 100   Total Pages: 5   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103318174]
IC50 23.73Affinity value against N-methyl-D-aspartate (NMDA) receptor using [3H]-CGS- 19755 in glutamate radioligand binding assay. [AID144463, Type: Literature]
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2
[SID11113958]
p450-cyp1a2 [AID410, Type: confirmatory]cytochrome P450 1A2 [Homo sapiens] [gi:73915100]
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3
[SID103318174]
IC50 100Affinity against Ionotropic glutamate receptor AMPA using [3H]AMPA in selective radioligand binding assay [AID92205, Type: Literature]
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4
[SID103318174]
IC50 100Affinity value against Ionotropic glutamate receptor kainate using [3H]-kainic acid in selective radioligand binding assay. [AID93555, Type: Literature]
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5
[SID103318174]
IC50 100In vitro ability to displace [3H]glutamate binding to metabotropic glutamate receptors in rat forebrain membranes [AID108348, Type: Literature]
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6
[SID11113958]
Cytochrome panel assay with activity outcomes [AID1851, Type: other]
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7
[SID11113958]
Potency Quantitative High-Throughput Screen for Regulators of Epigenetic Control [AID1865, Type: confirmatory]
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8
[SID11113958]
Potency qHTS Assay for Compounds that Induce Erasure of Genomic Imprints [AID1948, Type: confirmatory]
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9
[SID11113958]
Potency qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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10
[SID11113958]
Potency qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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11
[SID11113958]
qHTS Assay for Inhibitors of PDE-IV [AID607, Type: confirmatory]cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform 1 [Homo sapiens] [gi:82799486]
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12
[SID11113958]
qHTS Assay for Inhibitors of YjeE [AID605, Type: confirmatory]tRNA threonylcarbamoyladenosine biosynthesis protein TsaE [gi:84028058]
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13
[SID11113958]
Potency Inhibitors of Regulator of G Protein Signaling (RGS) 4: qHTS [AID504845, Type: confirmatory]regulator of G-protein signaling 4 [Homo sapiens] [gi:86301163]
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14
[SID11113958]
Potency qHTS for Inhibitors of binding or entry into cells for Lassa Virus [AID720533, Type: confirmatory]
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15
[SID11113958]
Potency qHTS Assay for Inhibitors of Firefly Luciferase [AID411, Type: confirmatory]Luciferase [Photinus pyralis] [gi:160794]
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16
[SID11113958]
Potency qHTS for Inhibitors of binding or entry into cells for Marburg Virus [AID720532, Type: confirmatory]gene 4 small orf - Marburg virus [Marburg marburgvirus] [gi:420597]
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17
[SID11113958]
Potency qHTS Assay for Inhibitors and Activators of N370S glucocerebrosidase as a Potential Chaperone Treatment of Gaucher Disease [AID2101, Type: confirmatory]glucocerebrosidase [Homo sapiens] [gi:496369]
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18
[SID11113958]
Potency qHTS Assay for Inhibitors of Human alpha-Galactosidase at pH 4.5. [AID1467, Type: confirmatory]alpha-galactosidase [Homo sapiens] [gi:757912]
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19
[SID11113958]
Potency qHTS Assay for Inhibitors and Activators of Human alpha-Galactosidase From Spleen Homogenate [AID2107, Type: confirmatory]alpha-galactosidase [Homo sapiens] [gi:757912]
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20
[SID11113958]
Potency Counterscreen for Luciferase (Kinase-Glo TM) Inhibition [AID1379, Type: confirmatory]luciferase [Photuris pennsylvanica] [gi:1669525]
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