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CHEMBL431998 (CID 6604828) - Compound BioActivity Data
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BioActivity Outcomes:
Active(2)
 
 
Inactive(89)
 
 
Inconclusive(5)
 
 
Unspecified(4)
 
 
Top Targets:
p450(9)
 
 
 
 
HSD10-like SD..(4)
 
 
PLDc mTdp1 2(3)
 
 
Tubulin-bindi..(3)
 
 
 
IMPase(2)
 
 
BioAssay Types:
Confirmatory(89)
 
 
 
 
Literature(4)
 
 
 
Screening(1)
 
 
BioActivity Types:
Potency(69)
 
 
 
IC50(4)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 90    Data Row: 100   Total Pages: 5   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103318174]
IC50 23.73Affinity value against N-methyl-D-aspartate (NMDA) receptor using [3H]-CGS- 19755 in glutamate radioligand binding assay. [AID144463, Type: Literature]
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2
[SID11113958]
p450-cyp1a2 [AID410, Type: confirmatory]cytochrome P450 1A2 [Homo sapiens] [gi:73915100]
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3
[SID103318174]
IC50 100Affinity against Ionotropic glutamate receptor AMPA using [3H]AMPA in selective radioligand binding assay [AID92205, Type: Literature]
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4
[SID103318174]
IC50 100Affinity value against Ionotropic glutamate receptor kainate using [3H]-kainic acid in selective radioligand binding assay. [AID93555, Type: Literature]
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5
[SID103318174]
IC50 100In vitro ability to displace [3H]glutamate binding to metabotropic glutamate receptors in rat forebrain membranes [AID108348, Type: Literature]
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6
[SID11113958]
Cytochrome panel assay with activity outcomes [AID1851, Type: other]
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7
[SID11113958]
Potency Quantitative High-Throughput Screen for Regulators of Epigenetic Control [AID1865, Type: confirmatory]
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8
[SID11113958]
Potency qHTS Assay for Compounds that Induce Erasure of Genomic Imprints [AID1948, Type: confirmatory]
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9
[SID11113958]
Potency qHTS Assay for Allosteric/Competitive Inhibitors of Caspase-1: Spectroscopic Profiling in AFC Spectral Region [AID923, Type: confirmatory]
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10
[SID11113958]
Potency Counterscreen qHTS for Inhibitors of Tau Fibril Formation, Fluorescence Polarization [AID1463, Type: confirmatory]
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11
[SID11113958]
Potency qHTS Assay for Lipid Storage Modulators [AID1519, Type: confirmatory]
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12
[SID11113958]
Potency qHTS Assay for Compounds Blocking the Interaction Between CBF-beta and RUNX1 for the Treatment of Acute Myeloid Leukemia [AID1477, Type: confirmatory]
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13
[SID11113958]
Potency qHTS for Inhibitors of binding or entry into cells for Lassa Virus [AID720533, Type: confirmatory]
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14
[SID11113958]
qHTS Assay for Inhibitors of YjeE [AID605, Type: confirmatory]tRNA threonylcarbamoyladenosine biosynthesis protein TsaE [gi:84028058]
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15
[SID11113958]
Potency qHTS Assay for Inhibitors of HADH2 (Hydroxyacyl-Coenzyme A Dehydrogenase, Type II) [AID886, Type: confirmatory]Chain A, The Structure Of Wild-Type Human Hadh2 (17beta-Hydroxysteroid Dehydrogenase Type 10) Bound To Nad+ At 1.2 A [gi:122921310]
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16
[SID11113958]
Potency qHTS Assay for Inhibitors of HSD17B4, hydroxysteroid (17-beta) dehydrogenase 4 [AID893, Type: confirmatory]Chain A, The Structure Of Wild-Type Human Hadh2 (17beta-Hydroxysteroid Dehydrogenase Type 10) Bound To Nad+ At 1.2 A [gi:122921310]
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17
[SID11113958]
Potency qHTS for Inhibitors of binding or entry into cells for Marburg Virus [AID720532, Type: confirmatory]gene 4 small orf - Marburg virus [Marburg marburgvirus] [gi:420597]
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18
[SID11113958]
Potency qHTS Assay for Allosteric/Competitive Inhibitors of Caspase-7 [AID889, Type: confirmatory]Caspase-7 [gi:1730092]
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19
[SID11113958]
Potency qHTS Assay for Inhibitors of Bloom's syndrome helicase (BLM) [AID2528, Type: confirmatory]Bloom syndrome protein isoform 1 [Homo sapiens] [gi:4557365]
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20
[SID11113958]
Potency qHTS Assay for Identifying the Cell-Membrane Permeable IMPase Inhibitors [AID901, Type: confirmatory]Inositol monophosphatase [gi:44888968]
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