Bookmark and Share
trisodium 1-amino-4-[4-[[4-chloro-6-(4-sulfonatoanilino)-1,3,5-triazin-2-yl]amino]-3-sulfonatoanilino]-9,10-dioxoanthracene-2-sulfonate (CID 6604161) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(48)
 
 
Inactive(93)
 
 
Inconclusive(49)
 
 
Unspecified(1)
 
 
Top Targets:
ANK(5)
 
 
 
PLN02808(5)
 
 
p450(5)
 
 
 
 
Pyruvate Kina..(4)
 
 
 
 
Git3(4)
 
 
BioAssay Types:
Confirmatory(166)
 
 
 
 
 
Screening(12)
 
 
 
Literature(3)
 
 
 
Summary(1)
 
 
BioActivity Types:
Potency(140)
 
 
 
 
 
IC50(2)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 178    Data Row: 191   Total Pages: 4   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID50106952]
Potency 0.2512qHTS Validation Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1) [AID1705, Type: confirmatory]Chain A, Human Ape1 Endonuclease With Bound Abasic Dna And Mn2+ Ion [gi:6980812]
View
2
[SID56427256]
IC50 0.550579Dose Response Confirmation for DnaK Inhibitors [AID1462, Type: confirmatory]heat shock protein [Escherichia coli str. K-12 substr. MG1655] [gi:16130533]
View
3
[SID50106952]
Potency 0.631qHTS for Inhibitors of Polymerase Eta [AID588591, Type: confirmatory]DNA polymerase eta [Homo sapiens] [gi:5729982]
View
4
[SID50106952]
Potency 0.631qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1) [AID2517, Type: confirmatory]Chain A, Human Ape1 Endonuclease With Bound Abasic Dna And Mn2+ Ion [gi:6980812]
View
5
[SID11112078]
Potency 0.631qHTS Validation Assay for Activators of Leishmania Mexicana Pyruvate Kinase [AID959, Type: confirmatory]pyruvate kinase [Leishmania mexicana mexicana] [gi:290753097]
View
6
[SID50106952]
Potency 0.7079Confirmation qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1) [AID2572, Type: confirmatory]Chain A, Human Ape1 Endonuclease With Bound Abasic Dna And Mn2+ Ion [gi:6980812]
View
7
[SID50106952]
Potency 0.8913qHTS Assay for Inhibitors of RecQ-Like Dna Helicase 1 (RECQ1) [AID2549, Type: confirmatory]Chain A, Structure Of Human Recq-Like Helicase In Complex With A Dna Substrate [gi:282403581]
View
8
[SID50106952]
Potency 1qHTS Validation Assay for Inhibitors of RecQ-Like Dna Helicase 1 (RECQ1) [AID2353, Type: confirmatory]Chain A, Structure Of Human Recq-Like Helicase In Complex With A Dna Substrate [gi:282403581]
View
9
[SID11112078]
Potency 1qHTS Assay for Inhibitors of HADH2 (Hydroxyacyl-Coenzyme A Dehydrogenase, Type II) [AID886, Type: confirmatory]Chain A, The Structure Of Wild-Type Human Hadh2 (17beta-Hydroxysteroid Dehydrogenase Type 10) Bound To Nad+ At 1.2 A [gi:122921310]
View
10
[SID11112078]
Potency 1qHTS Assay for Inhibitors of HADH2 (Hydroxyacyl-Coenzyme A Dehydrogenase, Type II) [AID886, Type: confirmatory]Chain B, The Structure Of Wild-Type Human Hadh2 (17beta-Hydroxysteroid Dehydrogenase Type 10) Bound To Nad+ At 1.2 A [gi:122921311]
View
11
[SID50106952]
Potency 1.122qHTS Assay for Inhibitors of DNA Polymerase Beta [AID485314, Type: confirmatory]DNA polymerase beta [Homo sapiens] [gi:4505931]
View
12
[SID85231327]
Potency 1.5849qHTS Validation Assay for Inhibitors for MPP8 Chromodomain Interactions with Methylated Histone Tails [AID488949, Type: confirmatory]M-phase phosphoprotein 8 [Homo sapiens] [gi:41055989]
View
13
[SID11112078]
Potency 1.5849qHTS Assay for Inhibitors of HSD17B4, hydroxysteroid (17-beta) dehydrogenase 4 [AID893, Type: confirmatory]Chain B, The Structure Of Wild-Type Human Hadh2 (17beta-Hydroxysteroid Dehydrogenase Type 10) Bound To Nad+ At 1.2 A [gi:122921311]
View
14
[SID50106952]
Potency 1.5849qHTS for Inhibitors of Polymerase Iota [AID588590, Type: confirmatory]DNA polymerase iota [Homo sapiens] [gi:154350220]
View
15
[SID11112078]
Potency 1.5849qHTS Assay for Inhibitors of HSD17B4, hydroxysteroid (17-beta) dehydrogenase 4 [AID893, Type: confirmatory]Chain A, The Structure Of Wild-Type Human Hadh2 (17beta-Hydroxysteroid Dehydrogenase Type 10) Bound To Nad+ At 1.2 A [gi:122921310]
View
16
[SID17405842]
IC50 1.66433Dose Response Confirmation for DnaK Inhibitors [AID1462, Type: confirmatory]heat shock protein [Escherichia coli str. K-12 substr. MG1655] [gi:16130533]
View
17
[SID124881890]
Potency 1.9953qHTS Assay for the Inhibitors of Human Flap endonuclease 1 (FEN1). [AID588795, Type: confirmatory]flap endonuclease 1 [Homo sapiens] [gi:4758356]
View
18
[SID50106952]
Potency 2.2387qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a [AID504332, Type: confirmatory]euchromatic histone-lysine N-methyltransferase 2 [Homo sapiens] [gi:168985070]
View
19
[SID50106952]
Potency 2.8184Counterscreen qHTS for Inhibitors of Tau Fibril Formation, Fluorescence Polarization [AID1463, Type: confirmatory]
View
20
[SID124881890]
Potency 3.5481qHTS for Inhibitors of Polymerase Iota [AID588590, Type: confirmatory]DNA polymerase iota [Homo sapiens] [gi:154350220]
View
21
[SID50106952]
Potency 3.9811qHTS for Inhibitors of Tau Fibril Formation, Thioflavin T Binding [AID1460, Type: confirmatory]Microtubule-associated protein tau [Homo sapiens] [gi:92096784]
View
22
[SID50106952]
Potency 3.9811Counterscreen for APE1 Inhibitors: qHTS Validation Assay for Inhibitors of Endonuclease IV [AID1708, Type: confirmatory]endonuclease IV [Escherichia coli] [gi:405898]
View
23
[SID11112078]
Potency 4.4668qHTS for inhibitors of binding or entry into cells for Marburg Virus [AID540276, Type: confirmatory]gene 4 small orf - Marburg virus [gi:420597]
View
24
[SID85231327]
Potency 4.4668qHTS for inhibitors of binding or entry into cells for Marburg Virus [AID540276, Type: confirmatory]gene 4 small orf - Marburg virus [gi:420597]
View
25
[SID50106952]
Potency 4.4668qHTS for inhibitors of binding or entry into cells for Marburg Virus [AID540276, Type: confirmatory]gene 4 small orf - Marburg virus [gi:420597]
View
26
[SID85231327]
Potency 6.1078qHTS Fluorescence Polarization (FP) Assay for Inhibitors of MLL CXXC domain - DNA interaction: HTRF Assay [AID624162, Type: confirmatory]
View
27
[SID50106952]
Potency 6.3096qHTS Assay for Inhibitors of Bloom's syndrome helicase (BLM) [AID2528, Type: confirmatory]Bloom syndrome protein isoform 1 [Homo sapiens] [gi:4557365]
View
28
[SID50106952]
Potency 6.3096qHTS Validation Assay for Inhibitors of Bloom's syndrome helicase (BLM) [AID2364, Type: confirmatory]Bloom syndrome protein isoform 1 [Homo sapiens] [gi:4557365]
View
29
[SID11112078]
Potency 7.9433qHTS Assay for Inhibitors of Ubiquitin-specific Protease USP2a [AID927, Type: confirmatory]ubiquitin carboxyl-terminal hydrolase 2 isoform a [Homo sapiens] [gi:188528692]
View
30
[SID50106952]
Potency 8.9125Counterscreen for APE1 Inhibitors: Fluorescent Dye Displacement Validation Assay [AID1707, Type: confirmatory]
View
31
[SID50106952]
Potency 10Counterscreen for APE1 Inhibitors: qHTS Assay for Inhibitors of Endonuclease IV [AID2565, Type: confirmatory]endonuclease IV [Escherichia coli] [gi:405898]
View
32
[SID85231327]
Potency 10qHTS Fluorescence Polarization Assay for Inhibitors of MLL CXXC domain - DNA interaction [AID2662, Type: confirmatory]histone-lysine N-methyltransferase 2A isoform 2 precursor [Homo sapiens] [gi:56550039]
View
33
[SID50106952]
Potency 10qHTS for Inhibitors of Tau Fibril Formation, Fluorescence Polarization [AID1468, Type: confirmatory]Microtubule-associated protein tau [Homo sapiens] [gi:92096784]
View
34
[SID50106952]
Potency 15.8489qHTS Assay for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase) [AID894, Type: confirmatory]15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 [Homo sapiens] [gi:31542939]
View
35
[SID85231327]
Potency 17.8524qHTS Fluorescence Polarization (FP) Assay for Inhibitors of MLL CXXC domain - DNA interaction: Fluorescein FP [AID624160, Type: confirmatory]
View
36
[SID85231327]
Potency 17.8524qHTS Fluorescence Polarization (FP) Assay for Inhibitors of MLL CXXC domain - DNA interaction: Texas Red FP [AID624161, Type: confirmatory]
View
37
[SID50106952]
Potency 22.3872Total Fluorescence Counterscreen for Inhibitors of the Interaction of Thyroid Hormone Receptor and Steroid Receptor Coregulator 2 [AID1479, Type: confirmatory]thyroid hormone receptor beta [Homo sapiens] [gi:189491771]
View
38
[SID50106952]
Potency 25.1189qHTS Assay for Inhibitors of the ERK Signaling Pathway using a Homogeneous Screening Assay; Stimulation with EGF [AID1454, Type: confirmatory]mitogen-activated protein kinase 1 [Homo sapiens] [gi:66932916]
View
39
[SID17405842]
HTS for BAP1 Enzyme inhibitors [AID436, Type: screening]Ubiquitin carboxyl-terminal hydrolase BAP1 [gi:68565074]
View
40
[SID11112078]
p450-cyp1a2 [AID410, Type: confirmatory]cytochrome P450 1A2 [Homo sapiens] [gi:73915100]
View
41
[SID11112078]
qHTS Assay for Inhibitors of YjeE [AID605, Type: confirmatory]tRNA threonylcarbamoyladenosine biosynthesis protein TsaE [gi:84028058]
View
42
[SID17405842]
HTS of LOPAC library for Estrogen Receptor-alpha Coactivator Binding inhibitors [AID694, Type: confirmatory]Estrogen receptor 1 [Homo sapiens] [gi:118764400]
View
43
[SID11112078]
Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay with detergent) [AID584, Type: confirmatory]Chain A, Ampc Beta-Lactamase In Complex With 4-Methanesulfonylamino Benzoic Acid [gi:119389684]
View
44
[SID17405842]
HTS for inhibitors of bacterial DnaK [AID547, Type: other]heat shock protein [Escherichia coli str. K-12 substr. MG1655] [gi:16130533]
View
45
[SID11112078]
O-Glc NAc Transferase (sOGT) [AID447, Type: confirmatory]
View
46
[SID11112078]
qHTS Assay for Inhibitors of DNA Polymerase III Holoenzyme System [AID603, Type: confirmatory]
View
47
[SID163565008]
Fluorescence-based counterscreen assay of HCV NS3 helicase-DNA binding inhibitors in LOPAC1280: biochemical high-throughput screening assay to identify compounds that enhance or quench fluorescence of a Cy5-DNA-NS3h complex [AID687037, Type: Literature]
View
48
[SID163565008]
Fluorescence polarization based primary biochemical high throughput screening assay of LOPAC1280 to identify inhibitors of hepatitis C non-structural protein 3 helicase [AID687035, Type: Literature]NS3 [Hepatitis C virus] [gi:125541954]
View
49
[SID124881890]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
View
50
[SID11112078]
Potency 0.631qHTS Validation Assay for Inhibitors of Leishmania Mexicana Pyruvate Kinase [AID945, Type: confirmatory]pyruvate kinase [Leishmania mexicana mexicana] [gi:290753097]
View