Bookmark and Share
NCGC00015899-01 (CID 6603988) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(6)
 
 
Inactive(62)
 
 
Inconclusive(11)
 
 
Unspecified(1)
 
 
Top Targets:
p450(9)
 
 
 
 
HSD10-like SD..(4)
 
 
Pyruvate Kina..(4)
 
 
PLN02808(3)
 
 
Git3(2)
 
 
BioAssay Types:
Confirmatory(67)
 
 
 
 
BioActivity Types:
Potency(45)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 72    Data Row: 80   Total Pages: 2   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID11111748]
Potency 1qHTS Assay for Inhibitors and Substrates of Cytochrome P450 2D6 [AID891, Type: confirmatory]cytochrome P450 2D6 isoform 1 [Homo sapiens] [gi:40805836]
View
2
[SID11111748]
Potency 5.6234qHTS Assay for Antagonists of Acetylcholine Muscarinic M1 Receptor: Kinetic Measurement of Intracellular Calcium Response [AID943, Type: confirmatory]muscarinic acetylcholine receptor M1 [Rattus norvegicus] [gi:18249941]
View
3
[SID11111748]
Potency 7.0795qHTS Assay for Antagonists of Acetylcholine Muscarinic M1 Receptor: Measurement of IP-One Response [AID944, Type: confirmatory]muscarinic acetylcholine receptor M1 [Rattus norvegicus] [gi:18249941]
View
4
[SID11111748]
Potency 10qHTS Assay for Activators of Cytochrome P450 3A4 [AID885, Type: confirmatory]cytochrome P450 3A4 isoform 1 [Homo sapiens] [gi:13435386]
View
5
[SID11111748]
Cytochrome panel assay with activity outcomes [AID1851_2, Type: other]cytochrome P450 2D6 isoform 2 [Homo sapiens] [gi:68509921]
View
6
[SID11111748]
p450-cyp1a2 [AID410, Type: confirmatory]cytochrome P450 1A2 [Homo sapiens] [gi:73915100]
View
7
[SID11111748]
Cytochrome panel assay with activity outcomes [AID1851, Type: other]
View
8
[SID11111748]
Potency 10qHTS Assay for Inhibitors and Substrates of Cytochrome P450 3A4 [AID884, Type: confirmatory]cytochrome P450 3A4 isoform 1 [Homo sapiens] [gi:13435386]
View
9
[SID11111748]
Potency qHTS Assay for Identifying the Cell-Membrane Permeable IMPase Inhibitors [AID901, Type: confirmatory]Inositol monophosphatase 1 [gi:44888968]
View
10
[SID11111748]
Potency Counterscreen for Glucocerebrosidase Inhibitors: qHTS Assay for Rice alpha-Glucosidase at pH 5.0 [AID997, Type: confirmatory]putative alpha-glucosidase [Oryza sativa Japonica Group] [gi:52076901]
View
11
[SID11111748]
GR-GFP Redistribution [AID450, Type: confirmatory]glucocorticoid receptor isoform gamma [Homo sapiens] [gi:66528677]
View
12
[SID11111748]
GR-EFC Redistribution [AID451, Type: confirmatory]glucocorticoid receptor isoform gamma [Homo sapiens] [gi:66528677]
View
13
[SID11111748]
qHTS Assay for Inhibitors of PDE-IV [AID607, Type: confirmatory]cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform 1 [Homo sapiens] [gi:82799486]
View
14
[SID11111748]
qHTS Assay for Inhibitors of YjeE [AID605, Type: confirmatory]tRNA threonylcarbamoyladenosine biosynthesis protein TsaE [gi:84028058]
View
15
[SID11111748]
qHTS Multiplex Assay to Identify Dual Action Probes in a Cell Model of Huntington: Cytoprotection (ATP) [AID1471, Type: confirmatory]huntingtin [Homo sapiens] [gi:90903231]
View
16
[SID11111748]
qHTS Assay for Tau Filament Binding [AID596, Type: confirmatory]Microtubule-associated protein tau [Homo sapiens] [gi:92096784]
View
17
[SID11111748]
Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay with detergent) [AID584, Type: confirmatory]Chain A, Ampc Beta-Lactamase In Complex With 4-Methanesulfonylamino Benzoic Acid [gi:119389684]
View
18
[SID11111748]
Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay without detergent) [AID585, Type: confirmatory]Chain A, Ampc Beta-Lactamase In Complex With 4-Methanesulfonylamino Benzoic Acid [gi:119389684]
View
19
[SID11111748]
Potency qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53ts Cells at the Nonpermissive Temperature [AID902, Type: confirmatory]cellular tumor antigen p53 isoform a [Homo sapiens] [gi:120407068]
View
20
[SID11111748]
Potency qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53ts Cells at the Permissive Temperature [AID924, Type: confirmatory]cellular tumor antigen p53 isoform a [Homo sapiens] [gi:120407068]
View
21
[SID11111748]
Potency qHTS Assay for Identification of Small Molecule Agonists for Thrombopoietin (TPO) Signaling Pathway [AID917, Type: confirmatory]Thrombopoietin [Homo sapiens] [gi:120660324]
View
22
[SID11111748]
Potency qHTS Assay for Inhibitors of HSD17B4, hydroxysteroid (17-beta) dehydrogenase 4 [AID893, Type: confirmatory]Chain A, The Structure Of Wild-Type Human Hadh2 (17beta-Hydroxysteroid Dehydrogenase Type 10) Bound To Nad+ At 1.2 A [gi:122921310]
View
23
[SID11111748]
Potency qHTS Assay for Inhibitors of HADH2 (Hydroxyacyl-Coenzyme A Dehydrogenase, Type II) [AID886, Type: confirmatory]Chain A, The Structure Of Wild-Type Human Hadh2 (17beta-Hydroxysteroid Dehydrogenase Type 10) Bound To Nad+ At 1.2 A [gi:122921310]
View
24
[SID11111748]
Potency qHTS Assay for Inhibitors of HADH2 (Hydroxyacyl-Coenzyme A Dehydrogenase, Type II) [AID886, Type: confirmatory]Chain B, The Structure Of Wild-Type Human Hadh2 (17beta-Hydroxysteroid Dehydrogenase Type 10) Bound To Nad+ At 1.2 A [gi:122921311]
View
25
[SID11111748]
Potency qHTS Assay for Inhibitors of HSD17B4, hydroxysteroid (17-beta) dehydrogenase 4 [AID893, Type: confirmatory]Chain B, The Structure Of Wild-Type Human Hadh2 (17beta-Hydroxysteroid Dehydrogenase Type 10) Bound To Nad+ At 1.2 A [gi:122921311]
View
26
[SID11111748]
Potency qHTS Assay for Inhibitors of 12-hLO (12-human lipoxygenase) [AID1452, Type: confirmatory]arachidonate 12-lipoxygenase, 12S-type [Homo sapiens] [gi:154426292]
View
27
[SID11111748]
Potency qHTS Assay for Inhibitors of BRCT-Phosphoprotein Interaction (Red Fluorophore) [AID892, Type: confirmatory]Chain A, Solution Structure Of The Brct-C Domain From Human Brca1 [gi:159162802]
View
28
[SID11111748]
Potency qHTS Assay for Inhibitors of BRCT-Phosphoprotein Interaction (Green Fluorophore) [AID875, Type: confirmatory]Chain A, Solution Structure Of The Brct-C Domain From Human Brca1 [gi:159162802]
View
29
[SID11111748]
Potency qHTS Assay for Inhibitors of Ubiquitin-specific Protease USP2a [AID927, Type: confirmatory]ubiquitin carboxyl-terminal hydrolase 2 isoform a [Homo sapiens] [gi:188528692]
View
30
[SID11111748]
Potency qHTS Validation Assay for Activators of Leishmania Mexicana Pyruvate Kinase [AID959, Type: confirmatory]pyruvate kinase [Leishmania mexicana mexicana] [gi:290753097]
View
31
[SID11111748]
Potency qHTS Validation Assay for Inhibitors of Leishmania Mexicana Pyruvate Kinase [AID945, Type: confirmatory]pyruvate kinase [Leishmania mexicana mexicana] [gi:290753097]
View
32
[SID11111748]
Potency qHTS Assay for Inhibitors of 15-hLO-2 (15-human lipoxygenase 2) [AID881, Type: confirmatory]Arachidonate 15-lipoxygenase B [gi:317373425]
View
33
[SID11111748]
Potency qHTS Assay for Inhibitors of Firefly Luciferase [AID411, Type: confirmatory]Luciferase [Photinus pyralis] [gi:160794]
View
34
[SID11111748]
Potency Counterscreen for Glucocerebrosidase Inhibitors: qHTS Assay for Coffee Bean alpha-Galactosidase at pH 5.9 [AID998, Type: confirmatory]alpha-galactosidase [Homo sapiens] [gi:757912]
View
35
[SID11111748]
Potency Counterscreen for Glucocerebrosidase Inhibitors: qHTS Assay for Human alpha-Galactosidase at pH 4.5 [AID992, Type: confirmatory]alpha-galactosidase [Homo sapiens] [gi:757912]
View
36
[SID11111748]
Potency Counterscreen for Glucocerebrosidase Inhibitors: qHTS Assay for Coffee Bean alpha-Galactosidase at pH 4.5 [AID957, Type: confirmatory]alpha-galactosidase [Homo sapiens] [gi:757912]
View
37
[SID11111748]
Potency qHTS Assay for Allosteric/Competitive Inhibitors of Caspase-7 [AID889, Type: confirmatory]Caspase-7 [gi:1730092]
View
38
[SID11111748]
Potency qHTS Assay for Inhibitors of 15-hLO (15-human lipoxygenase) [AID887, Type: confirmatory]15-lipoxygenase [Homo sapiens] [gi:1832253]
View
39
[SID11111748]
JNK3 AlphaScreen Assay [AID530, Type: confirmatory]Mitogen-activated protein kinase 10 [gi:2499604]
View
40
[SID11111748]
Potency qHTS Assay for Inhibitors of RGS12 GoLoco Motif Activity (Green Fluorophore) [AID879, Type: confirmatory]RGS12 [Homo sapiens] [gi:3290016]
View
41
[SID11111748]
Schistosoma Mansoni Peroxiredoxins (Prx2) [AID448, Type: confirmatory]thioredoxin peroxidase [Schistosoma mansoni] [gi:4325211]
View
42
[SID11111748]
Potency qHTS Assay for Inhibitors and Substrates of Cytochrome P450 2C19 [AID899, Type: confirmatory]cytochrome P450 2C19 precursor [Homo sapiens] [gi:4503219]
View
43
[SID11111748]
Cytochrome panel assay with activity outcomes [AID1851_1, Type: other]cytochrome P450 2C19 precursor [Homo sapiens] [gi:4503219]
View
44
[SID11111748]
Potency qHTS Assay for Modulators of Hemoglobin Beta Chain Splicing [AID925, Type: confirmatory]hemoglobin subunit beta [Homo sapiens] [gi:4504349]
View
45
[SID11111748]
IkB Signaling [AID445, Type: confirmatory]NF-kappa-B inhibitor alpha [Homo sapiens] [gi:10092619]
View
46
[SID11111748]
qHTS Assay for Spectroscopic Profiling in Resorufin Spectral Region [AID588, Type: other]
View
47
[SID11111748]
qHTS Assay for Spectroscopic Profiling in 4-MU Spectral Region [AID589, Type: other]
View
48
[SID11111748]
qHTS Assay for Spectroscopic Profiling in A350 Spectral Region [AID590, Type: other]
View
49
[SID11111748]
qHTS Assay for Spectroscopic Profiling in A488 Spectral Region [AID591, Type: other]
View
50
[SID11111748]
qHTS Assay for Spectroscopic Profiling in A647 Spectral Region [AID592, Type: other]
View