Bookmark and Share
4-(3-(2-propyl-3-hydroxy-4-acetyl)phenoxy)propyloxyphenoxy acetic acid (CID 6603901) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(30)
 
 
Inactive(715)
 
 
Inconclusive(87)
 
 
Unspecified(17)
 
 
Top Targets:
7tm 4(43)
 
 
 
NR LBD PPAR(40)
 
 
 
 
 
p450(11)
 
 
 
 
NR LBD ER(10)
 
 
 
bZIP NFE2-lik..(9)
 
 
 
 
BioAssay Types:
Confirmatory(416)
 
 
 
 
 
Screening(328)
 
 
 
Literature(52)
 
 
 
 
 
Summary(25)
 
 
 
 
BioActivity Types:
Potency(394)
 
 
 
 
 
EC50(16)
 
 
 
 
IC50(12)
 
 
 
AC50(5)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 748    Data Row: 849   Total Pages: 43   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144212730]
Ratio Potency (uM) 0.00616448qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway: Summary [AID743227, Type: summary]peroxisome proliferator-activated receptor delta [Homo sapiens] [gi:216409690]
View
2
[SID144212730]
Potency-Replicate_1 0.011qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway [AID743212, Type: confirmatory]peroxisome proliferator-activated receptor delta [Homo sapiens] [gi:216409690]
View
3
[SID103399375]
EC50 0.021Agonist activity at human GAL4-fused PPARdelta ligand binding domain expressed in COS-1 cells after 20 hrs by luciferase reporter gene transactivation assay [AID712385, Type: Literature]Peroxisome proliferator-activated receptor delta [gi:417522]
View
4
[SID103399375]
EC50 0.039Transactivation of GAL4-fused human PPARdelta ligand binding domain transfected in african green monkey COS7 cells by luciferase reporter gene assay [AID709644, Type: Literature]Peroxisome proliferator-activated receptor delta [gi:417522]
View
5
[SID103399375]
EC50 0.125Activity at PPARbeta/delta by luciferase reporter gene transactivation assay in COS7 cells [AID270378, Type: Literature]Peroxisome proliferator-activated receptor delta [gi:417522]
View
6
[SID144212730]
Ratio Potency (uM) 0.149015qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor gamma (PPARg) signaling pathway: Summary [AID743140, Type: summary]peroxisome proliferator activated receptor gamma [Homo sapiens] [gi:216409692]
View
7
[SID144212730]
Potency-Replicate_1 0.2754qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor gamma (PPARg) signaling pathway [AID743094, Type: confirmatory]peroxisome proliferator activated receptor gamma [Homo sapiens] [gi:216409692]
View
8
[SID103399375]
EC50 0.53Agonist activity for Human PPAR delta receptor in transcriptional activation assay [AID91241, Type: Literature]Peroxisome proliferator-activated receptor delta [gi:417522]
View
9
[SID103399375]
EC50 0.64Transactivation of GAL4-fused PPARbeta LBD expressed in HepG2 cells after 20 hrs by luminescence assay [AID652614, Type: Literature]
View
10
[SID103399375]
EC50 0.65Transactivation of GAL4-fused PPARbeta (delta) ligand binding domain transfected in human HepG2 cells after 20 hrs by luciferase reporter gene assay [AID696369, Type: Literature]
View
11
[SID103399375]
EC50 0.977Activity at PPARalpha by luciferase reporter gene transactivation assay in COS7 cells [AID270379, Type: Literature]Peroxisome proliferator-activated receptor alpha [gi:3041727]
View
12
[SID103399375]
EC50 1.824Activity at PPARgamma by luciferase reporter gene transactivation assay in COS7 cells [AID270380, Type: Literature]Peroxisome proliferator-activated receptor gamma [gi:13432234]
View
13
[SID56463274]
AC50_uM 2.54Mycobacterium tuberculosis BioA enzyme inhibitor Measured in Biochemical System Using Plate Reader - 2163-02_Inhibitor_Dose_CherryPick_Activity [AID651683, Type: confirmatory]bioA [Mycobacterium tuberculosis UT205] [gi:378544807]
View
14
[SID103399375]
EC50 3.8Agonist activity for murine PPAR delta receptor in transcriptional activation assay [AID141908, Type: Literature]Peroxisome proliferator-activated receptor delta [gi:548577]
View
15
[SID103399375]
EC50 5.5Agonist activity for Human PPAR gamma receptor in transcriptional activation assay [AID91246, Type: Literature]Peroxisome proliferator-activated receptor gamma [gi:13432234]
View
16
[SID103399375]
EC50 10Agonist activity for murine PPAR gamma receptor in transcriptional activation assay [AID141913, Type: Literature]Peroxisome proliferator-activated receptor gamma [gi:13432235]
View
17
[SID11111371]
Potency 10qHTS Assay for Inhibitors and Substrates of Cytochrome P450 2C9 [AID883, Type: confirmatory]cytochrome P450 2C9 precursor [Homo sapiens] [gi:13699818]
View
18
[SID103399375]
EC50 10Agonist activity for Human PPAR alpha receptor in transcriptional activation assay [AID91237, Type: Literature]Peroxisome proliferator-activated receptor alpha [gi:3041727]
View
19
[SID26753592]
Potency 11.2202qHTS assay for small molecule agonists of the peroxisome proliferator-activated receptor alpha (PPARalpha) signaling pathway [AID651778, Type: confirmatory]Peroxisome proliferator-activated receptor alpha [gi:3041727]
View
20
[SID90341011]
Potency 50.1187Inhibitors of the vitamin D receptor (VDR): qHTS [AID504847, Type: confirmatory]vitamin D3 receptor isoform VDRA [Homo sapiens] [gi:63054845]
View