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Emetine (CID 6603320) - Compound BioActivity Data
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BioActivity Outcomes:
Probe(2)
 
 
Active(226)
 
 
Inactive(727)
 
 
Inconclusive(32)
 
 
Unspecified(11)
 
 
Top Targets:
7TM GPCR Srx(25)
 
 
7TM GPCR Srsx(23)
 
 
 
Bcl-2 like(16)
 
 
 
 
alkPPc(14)
 
 
Tryp SPc(9)
 
 
BioAssay Types:
Screening(565)
 
 
 
 
 
Confirmatory(342)
 
 
 
 
 
Literature(26)
 
 
 
 
 
Summary(2)
 
 
BioActivity Types:
Potency(158)
 
 
 
 
 
IC50(54)
 
 
 
 
EC50(24)
 
 
 
AC50(14)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 919    Data Row: 998   Total Pages: 50   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID855836]
Summary of probe development efforts to identify inhibitors of Retinoblastoma binding protein 9 (RBBP9): Ester Oxime Scaffold [AID2299, Type: summary]putative hydrolase RBBP9 [Homo sapiens] [gi:24119166]
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2
[SID855836]
Summary of probe development efforts to identify inhibitors of Retinoblastoma binding protein 9 (RBBP9). [AID1790, Type: summary]putative hydrolase RBBP9 [Homo sapiens] [gi:24119166]
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3
[SID855836]
SAMPLE2_EC50_uM 0.00682Fluorescence Cell-Based Dose Response to Characterize Compounds Cytotoxic to RAS-Dependent BJeLR Fibroblast [AID2610, Type: confirmatory]
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4
[SID855836]
EC50_uM 0.00763Fluorescence Cell-Based Dose Response to Characterize Compounds Cytotoxic to RAS-Dependent BJ-TERT-LT-ST Fibroblast [AID2631, Type: confirmatory]
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5
[SID855836]
EC50_uM 0.00912Fluorescence Cell-Based Dose Response to Characterize Compounds Cytotoxic to Non-Viral Oncogenic DRD Fibroblast [AID2633, Type: confirmatory]
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6
[SID855836]
EC50_uM 0.0103Fluorescence Cell-Based Dose Response to Characterize Compounds Cytotoxic to RAS-Dependent BJ-TERT Fibroblast [AID2635, Type: confirmatory]
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7
[SID855836]
Potency 0.0231qHTS for Inhibitors of TGF-b: Confirmation of Cherry Picks [AID720534, Type: confirmatory]Smad3 [Homo sapiens] [gi:18418623]
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8
[SID855836]
EC50 0.03Luminescence Cell-Based Dose Response to Identify Inhibitors of Luciferase Translation or Activity in H4-C Neuroglioblastoma Cells [AID2458, Type: confirmatory]
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9
[SID855836]
IC50 0.03457Luminescence-based dose response cell-based high throughput screening assay for cytotoxic compounds using the IEC-6 intestinal epithelial cell line. [AID1972, Type: confirmatory]
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10
[SID855836]
Potency 0.0366qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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11
[SID855836]
EC50 0.052Luminescence Cell-Based HTS Dose Confimation to Identify Inhibitors of of 5'UTR Stem-Loop Driven Alpha-Synuclein mRNA Translation in H4 Neuroglioblastoma Cells [AID2454, Type: confirmatory]
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12
[SID855836]
Potency 0.0738Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation [AID504834, Type: confirmatory]
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13
[SID855836]
Potency 0.0828Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation [AID504832, Type: confirmatory]
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14
[SID855836]
Potency 0.0891qHTS for Inhibitors of TGF-b [AID588855, Type: confirmatory]Smad3 [Homo sapiens] [gi:18418623]
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15
[SID855836]
EC50 0.09Fluorescent HTS Cytotoxicity/Cell viability assay (HPDE-C7K cells) [AID431, Type: confirmatory]
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16
[SID855836]
EC50 0.1Luminescence Cell-Based Dose Confimation HTS to Identify Inhibitors of of 5'UTR Stem-Loop Driven Alpha-Synuclein mRNA Translation in H4 Neuroglioblastoma Cells [AID1988, Type: confirmatory]
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17
[SID855836]
EC50 0.1Luminescence Cell-Based Dose Response HTS to Identify Inhibitors of Luciferase Translation or Activity in H4 Neuroglioblastoma Cells [AID1990, Type: confirmatory]
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18
[SID855836]
EC50 0.1Luminescence Cell-Based Dose Response HTS to Identify Inhibitors of 5'UTR Stem-Loop Driven Prion Protein mRNA Translation in H4 Neuroglioblastoma Cells [AID1994, Type: confirmatory]
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19
[SID855836]
EC50 0.101Luminescence Cell-Based Dose Response to Identify Inhibitors of 5'UTR Stem-Loop Driven Prion Protein mRNA Translation in H4-C Neuroglioblastoma Cells [AID2452, Type: confirmatory]
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20
[SID855836]
Potency 0.1032qHTS for inhibitors of binding or entry into cells for Marburg Virus [AID540276, Type: confirmatory]gene 4 small orf - Marburg virus [Marburg marburgvirus] [gi:420597]
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