Dichloroacetic Acid (CID 6597) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(6)
 
 
Inactive(414)
 
 
Inconclusive(9)
 
 
Unspecified(24)
 
 
Top Targets:
NR LBD PPAR(10)
 
 
 
NR LBD TR(8)
 
 
 
NR LBD VDR(5)
 
 
NR LBD ROR li..(5)
 
 
TRP 2(5)
 
 
BioAssay Types:
Confirmatory(211)
 
 
 
Screening(124)
 
 
 
Literature(83)
 
 
 
BioActivity Types:
Potency(161)
 
 
 
IC50(10)
 
 
 
EC50(2)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 344    Data Row: 453   Total Pages: 10   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID48413570]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary SingleCellCall Results [AID1189, Type: other]
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2
[SID48413570]
DSSTox (CPDBAS) Carcinogenic Potency Database Salmonella Mutagenicity [AID1194, Type: other]
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3
[SID48413570]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary Mouse Bioassay Results [AID1199, Type: other]
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4
[SID48413570]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary MultiCellCall Results [AID1205, Type: other]
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5
[SID48413570]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary Rat Bioassay Results [AID1208, Type: other]
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6
[SID48415880]
DSSTox (FDAMDD) FDA Maximum (Recommended) Daily Dose Database [AID1195, Type: other]
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7
[SID103176116]
EC50 100In vitro effective concentration in normal human dermal fibroblasts [AID90949, Type: Literature]
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8
[SID103176116]
IC50 2000In vitro inhibitory activity against pyruvate dehydrogenase kinase was determined [AID162967, Type: Literature]
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9
[SID103176116]
Lipophilicity determined as logarithm of the partition coefficient in the alkane/water system [AID237685, Type: Literature]
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10
[SID103176116]
Mutagenic activity in Salmonella Typhimurium TA100 assessed as logarithm of his+ revertant number increasing activity by amens test [AID384212, Type: Literature]
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11
[SID17389935]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838, Type: other]
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12
[SID103176116]
Substrates for human cytosolic glutathione transferase GSTZ1 [AID589015, Type: other]Maleylacetoacetate isomerase [gi:269849671]
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13
[SID103176116]
In vivo activity in a diabetic mouse at a dose of 1000 umol/kg/day on day 3 after 2 hr [AID131105, Type: Literature]
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14
[SID103176116]
In vivo activity in a diabetic mouse at a dose of 1000 umol/kg/day on day 3 after 4 hr [AID131106, Type: Literature]
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15
[SID103176116]
In vivo activity in a diabetic mouse at a dose of 1000 umol/kg/day on day 3 after 6 hr [AID131107, Type: Literature]
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16
[SID103176116]
In vivo activity in a diabetic mouse at a dose of 1000 umol/kg/day on day1 after 2 hours [AID131108, Type: Literature]
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17
[SID103176116]
In vivo activity in a diabetic mouse at a dose of 1000 umol/kg/day on day1 after 4 hr [AID131109, Type: Literature]
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18
[SID103176116]
In vivo activity in a diabetic mouse at a dose of 1000 umol/kg/day on day1 after 6 hr [AID131110, Type: Literature]
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19
[SID103176116]
Partition coefficient (logP) [AID23251, Type: Literature]
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20
[SID103176116]
Partition coefficient (logP) (benzene) [AID23252, Type: Literature]
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21
[SID103176116]
Partition coefficient (logP) (carbon tetrachloride) [AID23253, Type: Literature]
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22
[SID103176116]
Partition coefficient (logP) (chloroform) [AID23254, Type: Literature]
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23
[SID103176116]
Partition coefficient (logP) (ether) [AID23255, Type: Literature]
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24
[SID103176116]
Partition coefficient (logP) (hexane) [AID23256, Type: Literature]
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25
[SID26753010]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749, Type: Literature]
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26
[SID144204684]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838, Type: other]
View
27
[SID103176116]
Half life in human after iv administration [AID540213, Type: Literature]
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28
[SID103176116]
Volume of distribution at steady state in human after iv administration [AID540209, Type: Literature]
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29
[SID103176116]
Clearance in human after iv administration [AID540210, Type: Literature]
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30
[SID103176116]
Mean residence time in human after iv administration [AID540212, Type: Literature]
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31
[SID17389935]
Potency qHTS assay for small molecule disruptors of the mitochondrial membrane potential - 1 hr assay [AID651754, Type: confirmatory]
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32
[SID17389935]
Potency qHTS assay for small molecule disruptors of the mitochondrial membrane potential - 5 hr assay [AID651755, Type: confirmatory]
View
33
[SID49681803]
IC50 Identification of SV40 T antigen inhibitors: A route to novel anti-viral reagents [AID1903, Type: confirmatory]large T antigen [Simian virus 40] [gi:297591903]
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34
[SID49681803]
Fluorescence polarization-based primary biochemical high throughput screening assay to identify inhibitors of tRNA 2'-phosphotransferase (TPT1). [AID1962, Type: screening]likely tRNA 2'-phosphotransferase [Candida albicans SC5314] [gi:68476498]
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35
[SID26753010]
Potency qHTS Assay to Find Inhibitors of T. brucei phosphofructokinase: hit validation [AID492961, Type: confirmatory]ATP-dependent phosphofructokinase [Trypanosoma brucei] [gi:72386991]
View
36
[SID49681803]
Fluorescence polarization-based primary biochemical high throughput screening assay to identify inhibitors of the Epstein-Barr virus nuclear antigen 1 (EBNA-1). [AID1950, Type: screening]EBNA-1 protein [Human herpesvirus 4] [gi:23893623]
View
37
[SID49681803]
Counterscreen for inhibitors of EBNA-1: fluorescence polarization-based biochemical high throughput primary assay to identify inhibitors of the Epstein-Barr virus-encoded protein, ZTA. [AID2234, Type: screening]BZLF1 [Human herpesvirus 4] [gi:82503229]
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38
[SID49681803]
Fluorescence Polarization Cell-Free Homogeneous Primary HTS to Identify Inhibitors of the LANA Histone H2A/H2B Interaction [AID2629, Type: screening]LANA [Human herpesvirus 8] [gi:139472804]
View
39
[SID17389935]
Potency qHTS assay for small molecule agonists of peroxisome proliferator-activated receptor gamma signaling [AID588536, Type: confirmatory]peroxisome proliferator activated receptor gamma [Homo sapiens] [gi:216409692]
View
40
[SID17389935]
Potency qHTS assay for small molecule agonists of peroxisome proliferator-activated receptor gamma signaling [AID588536, Type: confirmatory]peroxisome proliferator activated receptor gamma [Homo sapiens] [gi:216409692]
View
41
[SID17389935]
Potency qHTS assay for small molecule agonists of peroxisome proliferator-activated receptor gamma signaling [AID588536, Type: confirmatory]peroxisome proliferator activated receptor gamma [Homo sapiens] [gi:216409692]
View
42
[SID17389935]
Potency qHTS assay for small molecule agonists of peroxisome proliferator-activated receptor gamma signaling [AID588536, Type: confirmatory]peroxisome proliferator activated receptor gamma [Homo sapiens] [gi:216409692]
View
43
[SID17389935]
Potency qHTS assay for small molecule antagonists of peroxisome proliferator-activated receptor gamma signaling [AID588537, Type: confirmatory]peroxisome proliferator activated receptor gamma [Homo sapiens] [gi:216409692]
View
44
[SID17389935]
Potency qHTS assay for small molecule antagonists of peroxisome proliferator-activated receptor gamma signaling [AID588537, Type: confirmatory]peroxisome proliferator activated receptor gamma [Homo sapiens] [gi:216409692]
View
45
[SID17389935]
Potency qHTS assay for small molecule antagonists of peroxisome proliferator-activated receptor gamma signaling [AID588537, Type: confirmatory]peroxisome proliferator activated receptor gamma [Homo sapiens] [gi:216409692]
View
46
[SID17389935]
Potency qHTS assay for small molecule antagonists of peroxisome proliferator-activated receptor gamma signaling [AID588537, Type: confirmatory]peroxisome proliferator activated receptor gamma [Homo sapiens] [gi:216409692]
View
47
[SID26753010]
Potency qHTS assay for small molecule agonists of peroxisome proliferator-activated receptor gamma signaling [AID588536, Type: confirmatory]peroxisome proliferator activated receptor gamma [Homo sapiens] [gi:216409692]
View
48
[SID26753010]
Potency qHTS assay for small molecule agonists of peroxisome proliferator-activated receptor gamma signaling [AID588536, Type: confirmatory]peroxisome proliferator activated receptor gamma [Homo sapiens] [gi:216409692]
View
49
[SID26753010]
Potency qHTS assay for small molecule agonists of peroxisome proliferator-activated receptor gamma signaling [AID588536, Type: confirmatory]peroxisome proliferator activated receptor gamma [Homo sapiens] [gi:216409692]
View
50
[SID26753010]
Potency qHTS assay for small molecule agonists of peroxisome proliferator-activated receptor gamma signaling [AID588536, Type: confirmatory]peroxisome proliferator activated receptor gamma [Homo sapiens] [gi:216409692]
View