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Dichloroacetic Acid (CID 6597) - Compound BioActivity Data
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BioActivity Outcomes:
Active(7)
 
 
Inactive(688)
 
 
Inconclusive(23)
 
 
Unspecified(24)
 
 
Top Targets:
NR LBD PPAR(34)
 
 
 
NR LBD AR(25)
 
 
 
NR LBD ER(25)
 
 
 
NR LBD TR(17)
 
 
 
 
NR LBD VDR(17)
 
 
BioAssay Types:
Confirmatory(417)
 
 
 
 
Screening(131)
 
 
 
Literature(84)
 
 
 
Summary(72)
 
 
 
BioActivity Types:
Potency(420)
 
 
 
 
IC50(10)
 
 
 
EC50(2)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 443    Data Row: 742   Total Pages: 38   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144210737]
Potency-Replicate_1 61.1306qHTS assay to identify small molecule agonists of the thyroid receptor (TR) signaling pathway [AID743066, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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2
[SID48413570]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary SingleCellCall Results [AID1189, Type: other]
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3
[SID48413570]
DSSTox (CPDBAS) Carcinogenic Potency Database Salmonella Mutagenicity [AID1194, Type: other]
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4
[SID48415880]
DSSTox (FDAMDD) FDA Maximum (Recommended) Daily Dose Database [AID1195, Type: other]
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5
[SID48413570]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary Mouse Bioassay Results [AID1199, Type: other]
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6
[SID48413570]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary MultiCellCall Results [AID1205, Type: other]
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7
[SID48413570]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary Rat Bioassay Results [AID1208, Type: other]
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8
[SID103176116]
EC50 100In vitro effective concentration in normal human dermal fibroblasts [AID90949, Type: Literature]
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9
[SID103176116]
IC50 2000In vitro inhibitory activity against pyruvate dehydrogenase kinase was determined [AID162967, Type: Literature]
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10
[SID103176116]
Lipophilicity determined as logarithm of the partition coefficient in the alkane/water system [AID237685, Type: Literature]
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11
[SID103176116]
Mutagenic activity in Salmonella Typhimurium TA100 assessed as logarithm of his+ revertant number increasing activity by amens test [AID384212, Type: Literature]
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12
[SID103176116]
In vivo activity in a diabetic mouse at a dose of 1000 umol/kg/day on day 3 after 2 hr [AID131105, Type: Literature]
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13
[SID103176116]
In vivo activity in a diabetic mouse at a dose of 1000 umol/kg/day on day 3 after 4 hr [AID131106, Type: Literature]
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14
[SID103176116]
In vivo activity in a diabetic mouse at a dose of 1000 umol/kg/day on day 3 after 6 hr [AID131107, Type: Literature]
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15
[SID103176116]
In vivo activity in a diabetic mouse at a dose of 1000 umol/kg/day on day1 after 2 hours [AID131108, Type: Literature]
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16
[SID103176116]
In vivo activity in a diabetic mouse at a dose of 1000 umol/kg/day on day1 after 4 hr [AID131109, Type: Literature]
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17
[SID103176116]
In vivo activity in a diabetic mouse at a dose of 1000 umol/kg/day on day1 after 6 hr [AID131110, Type: Literature]
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18
[SID103176116]
Partition coefficient (logP) [AID23251, Type: Literature]
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19
[SID103176116]
Partition coefficient (logP) (benzene) [AID23252, Type: Literature]
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20
[SID103176116]
Partition coefficient (logP) (carbon tetrachloride) [AID23253, Type: Literature]
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