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BioActivity Data for Compound acrylic acid (CID 6581)

BioActivity Outcomes:
Active(1)
 
 
Inactive(186)
 
 
Inconclusive(4)
 
 
Unspecified(4)
 
 
Top Targets:
NR LBD ER(7)
 
 
NR LBD AR(7)
 
 
NR LBD TR(5)
 
 
NR LBD GR(4)
 
 
 
ePHD KMT2A(3)
 
 
BioAssay Types:
Confirmatory(84)
 
 
 
Literature(65)
 
 
 
 
Summary(15)
 
 
Screening(2)
 
 
BioAssay Categories:
In vivo(14)
 
 
 
 
Biochemical(2)
 
 
 
Toxicity(7)
 
 
 
ADME(2)
 
 
BioActivity Types:
Potency(94)
 
 
 
IC50(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 116    Data Row: 195   Total Pages: 10   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID409854]
NCI In Vivo Anticancer Drug Screen. Data for tumor model P388 Leukemia (intraperitoneal) in B6D2F1 (BDF1) mice [AID328, Type: other]
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2
[SID104239701]
IC50 200Inhibition of Holtzman rat brain choline acetyltransferase using [1-14C-acetyl]-CoA as substrate at 1 mM incubated 20 mins prior to substrate addition measured after 30 mins by liquid scintillation counting analysis [AID1144084, Type: Literature]Choline O-acetyltransferase [gi:416805]
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3
[SID104239701]
Toxicity in po dosed mouse [AID498775, Type: Literature]
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4
[SID104239701]
In-vivo blood to lung partition coefficients of the compound, logP(lung) in rat [AID603955, Type: Literature]
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5
[SID29218004]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749, Type: Literature]
View
6
[SID29218004]
Potency 0.287S16 Schwann cell PMP22 intronic element firefly luciferase assay [AID624032, Type: confirmatory]peripheral myelin protein 22 [Rattus norvegicus] [gi:8393992]
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7
[SID144205925]
Potency-Replicate_1 23.7101qHTS assay for small molecules that induce genotoxicity in human embryonic kidney cells expressing luciferase-tagged ATAD5 - cell viability [AID651634, Type: confirmatory]
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8
[SID144205925]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line - cell viability counter screen [AID743041, Type: confirmatory]
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9
[SID144205925]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway - cell viability counter screen [AID743064, Type: confirmatory]
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10
[SID144205925]
Potency-Replicate_1 qHTS assay for small molecule agonists of the p53 signaling pathway - cell viability [AID651633, Type: confirmatory]
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11
[SID144205925]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway - cell viability counter screen [AID743074, Type: confirmatory]
View
12
[SID144205925]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line - cell viability counter screen [AID743081, Type: confirmatory]
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13
[SID144205925]
Potency-Replicate_1 qHTS assay to identify aromatase inhibitors - cell viability counter screen [AID743084, Type: confirmatory]
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14
[SID144205925]
Potency-Replicate_1 qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway - cell viability counter screen [AID743086, Type: confirmatory]
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15
[SID144205925]
Potency qHTS Assay for Identifying Gametocytocidal Compounds [AID743244, Type: confirmatory]
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16
[SID29218004]
Potency Biochemical firefly luciferase enzyme assay for NPC [AID624030, Type: confirmatory]Luciferase [Photinus pyralis] [gi:160794]
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17
[SID29218004]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_20, Type: Literature]
View
18
[SID29218004]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_18, Type: Literature]
View
19
[SID29218004]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_15, Type: Literature]
View
20
[SID29218004]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_11, Type: Literature]
View