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diethylstilbestrol dipropionate (CID 657220) - Compound BioActivity Data
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BioActivity Outcomes:
Active(33)
 
 
Inactive(877)
 
 
Inconclusive(44)
 
 
Unspecified(7)
 
 
Top Targets:
7tm 4(48)
 
 
NR LBD ER(15)
 
 
 
alkPPc(14)
 
 
NR LBD PPAR(14)
 
 
 
 
Tryp SPc(13)
 
 
BioAssay Types:
Screening(598)
 
 
 
 
 
Confirmatory(292)
 
 
 
 
 
Summary(24)
 
 
 
 
Literature(23)
 
 
 
BioActivity Types:
Potency(232)
 
 
 
 
 
IC50(49)
 
 
 
 
EC50(14)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 878    Data Row: 961   Total Pages: 49   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144213030]
Potency-Replicate_1 0.0014qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway [AID743075, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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2
[SID144213030]
Ratio Potency (uM) 0.00255076qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway: Summary [AID743077, Type: summary]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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3
[SID855597]
Potency 1.9953qHTS Assay for Identification of Small Molecule Antagonists for Hypoxia Response Element Signaling Pathway [AID915, Type: confirmatory]hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) [Homo sapiens] [gi:32879895]
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4
[SID855597]
EC50 3.87Fluorescent HTS Cytotoxicity/Cell viability assay (HPDE-C7K cells) [AID431, Type: confirmatory]
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5
[SID855597]
EC50 4.6Fluorescent HTS Cytotoxicity/Cell viability assay (HPDE-C7 cells) [AID430, Type: confirmatory]
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6
[SID144213030]
Potency-Replicate_1 8.6349qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
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7
[SID144213030]
Ratio Potency (uM) 10.4614qHTS assay for small molecule disruptors of the mitochondrial membrane potential: Summary [AID720637, Type: summary]
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8
[SID144213030]
Potency-Replicate_1 15.3553qHTS assay for small molecule agonists of the p53 signaling pathway [AID651631, Type: confirmatory]Cellular tumor antigen p53 [gi:269849759]
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9
[SID144213030]
Ratio Potency (uM) 15.956qHTS assay for small molecule agonists of the p53 signaling pathway: Summary [AID720552, Type: summary]Cellular tumor antigen p53 [gi:269849759]
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10
[SID855597]
EC50 18.1314Estrogen Receptor-alpha Coactivator Binding Potentiators Dose Response Confirmation [AID737, Type: confirmatory]Estrogen receptor 1 [Homo sapiens] [gi:118764400]
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11
[SID144213030]
Potency-Replicate_1 30.6379qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway [AID743065, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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12
[SID56422143]
CC50 40Vero Cytoxicity Assay: A Cell Based Secondary Assay to Explore Cytotoxicity of Compounds that Inhibit Flavivirus Genomic Capping Enzyme [AID588742, Type: confirmatory]
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13
[SID144213030]
Ratio Potency (uM) 46.2327qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway: Summary [AID743078, Type: summary]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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14
[SID144213030]
Potency-Replicate_1 48.5577qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
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15
[SID144213030]
Potency-Replicate_1 48.5577qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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16
[SID144213030]
Potency-Replicate_1 54.4827qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway - cell viability counter screen [AID743064, Type: confirmatory]
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17
[SID144213030]
Potency-Replicate_1 54.4827qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
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18
[SID144213030]
Potency-Replicate_1 54.9477qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway - cell viability counter screen [AID743211, Type: confirmatory]
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19
[SID144213030]
Potency-Replicate_1 54.9477qHTS assay to identify small molecule agonists of the vitamin D receptor (VDR) signaling pathway - cell viability counter screen [AID743224, Type: confirmatory]
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20
[SID144213030]
Potency-Replicate_1 54.9477qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway [AID743069, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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