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BioActivity Data for Compound 2-butanol (CID 6568)

BioActivity Outcomes:
Active(1)
 
 
Inactive(249)
 
 
Inconclusive(11)
 
 
Unspecified(6)
 
 
Top Targets:
NR LBD PPAR(13)
 
 
 
NR LBD ER(9)
 
 
 
NR LBD AR(9)
 
 
NR LBD TR(7)
 
 
 
NR LBD VDR(6)
 
 
 
BioAssay Types:
Confirmatory(223)
 
 
 
 
Summary(28)
 
 
 
Literature(6)
 
 
 
BioAssay Categories:
Toxicity(40)
 
 
 
 
ADME(4)
 
 
BioActivity Types:
Potency(208)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 255    Data Row: 267   Total Pages: 14   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID48414954]
DSSTox (EPAFHM) EPA Fathead Minnow Acute Toxicity [AID1188, Type: other]
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2
[SID103226169]
GI50 28707.8Toxicity in Tetrahymena pyriformis [AID1094728, Type: confirmatory]
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3
[SID103226169]
LC50 2.99916e+07Toxicity determined using Golden Orfe Fish Test [AID101345, Type: Literature]
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4
[SID103226169]
Toxicity determined using Tadpole Narcosis Test [AID212400, Type: Literature]
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5
[SID103226169]
Binding affinity to beta cyclodextrin [AID346025, Type: Literature]
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6
[SID103226169]
Octanol-water partition coefficient, log P of the compound [AID1145366, Type: Literature]
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7
[SID17389639]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838, Type: other]
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8
[SID17389639]
Potency 0.2512qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1) [AID2517, Type: confirmatory]Chain A, Human Ape1 Endonuclease With Bound Abasic Dna And Mn2+ Ion [gi:6980812]
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9
[SID17389639]
Potency 7.9433qHTS Assay for Agonists of the Thyroid Stimulating Hormone Receptor: Activators of Intracellular cAMP Concentrations in Parental HEK 293 [AID938, Type: confirmatory]thyroid stimulating hormone receptor [Homo sapiens] [gi:38016895]
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10
[SID144208290]
Potency-Replicate_1 14.0341qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway [AID743065, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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11
[SID144208290]
Potency-Replicate_1 qHTS assay to identify small molecule agonists of the thyroid receptor (TR) signaling pathway [AID743066, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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12
[SID144208290]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line - cell viability counter screen [AID743081, Type: confirmatory]
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13
[SID144208290]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line [AID743080, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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14
[SID144208290]
ER Potency (uM) qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line: Summary [AID743091, Type: summary]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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15
[SID17389639]
IkB Signaling [AID445, Type: confirmatory]NF-kappa-B inhibitor alpha [Homo sapiens] [gi:10092619]
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16
[SID17389639]
Potency qHTS Assay for Enhancers of SMN2 Splice Variant Expression [AID1458, Type: confirmatory]survival motor neuron protein isoform d [Homo sapiens] [gi:10937869]
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17
[SID17389639]
Potency qHTS Assay for Inhibitors and Substrates of Cytochrome P450 3A4 [AID884, Type: confirmatory]cytochrome P450 3A4 isoform 1 [Homo sapiens] [gi:13435386]
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18
[SID17389639]
Potency qHTS Assay for Activators of Cytochrome P450 3A4 [AID885, Type: confirmatory]cytochrome P450 3A4 isoform 1 [Homo sapiens] [gi:13435386]
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19
[SID17389639]
Potency qHTS Assay for Allosteric/Competitive Inhibitors of Caspase-1 [AID900, Type: confirmatory]caspase-1 isoform alpha precursor [Homo sapiens] [gi:15431328]
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20
[SID17389639]
Potency qHTS assay for small molecule antagonists of peroxisome proliferator-activated receptor gamma signaling [AID588537, Type: confirmatory]peroxisome proliferator activated receptor gamma [Homo sapiens] [gi:216409692]
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