(-)-Isoprenaline hydrochloride (CID 656783) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(13)
 
 
Inactive(369)
 
 
Inconclusive(5)
 
 
Unspecified(1)
 
 
Top Targets:
7TM GPCR Srx(15)
 
 
7TM GPCR Srsx(11)
 
 
 
SLC5sbd CHT(6)
 
 
 
 
BRLZ(4)
 
 
Peptidase C48(4)
 
 
BioAssay Types:
Screening(280)
 
 
 
Confirmatory(97)
 
 
 
 
 
Literature(5)
 
 
BioActivity Types:
Potency(81)
 
 
 
 
 
IC50(13)
 
 
 
EC50(1)
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 388    Data Row: 388   Total Pages: 8   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID56463178]
Potency 0.0046qHTS assay of beta-arrestin-biased ligands of beta2-adrenergic receptor: Hit Validation with GloSensor [AID588790, Type: confirmatory]ADRB2 gene product [Homo sapiens] [gi:4501969]
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2
[SID56463178]
Potency 0.0046qHTS assay of beta-arrestin-biased ligands of beta2-adrenergic receptor: Hit Validation with GloSensor [AID588790, Type: confirmatory]ADRB2 gene product [Homo sapiens] [gi:4501969]
View
3
[SID56463178]
Potency 0.0046qHTS assay of beta-arrestin-biased ligands of beta2-adrenergic receptor: Hit Validation with GloSensor [AID588790, Type: confirmatory]ADRB2 gene product [Homo sapiens] [gi:4501969]
View
4
[SID56463178]
Potency 0.0046qHTS assay of beta-arrestin-biased ligands of beta2-adrenergic receptor: Hit Validation with GloSensor [AID588790, Type: confirmatory]ADRB2 gene product [Homo sapiens] [gi:4501969]
View
5
[SID56463178]
Potency 0.092qHTS assay of beta-arrestin-biased ligands of beta2-adrenergic receptor: Hit Validation [AID588463, Type: confirmatory]ADRB2 gene product [Homo sapiens] [gi:4501969]
View
6
[SID56463178]
Potency 0.092qHTS assay of beta-arrestin-biased ligands of beta2-adrenergic receptor: Hit Validation [AID588463, Type: confirmatory]ADRB2 gene product [Homo sapiens] [gi:4501969]
View
7
[SID56463178]
Potency 0.092qHTS assay of beta-arrestin-biased ligands of beta2-adrenergic receptor: Hit Validation [AID588463, Type: confirmatory]ADRB2 gene product [Homo sapiens] [gi:4501969]
View
8
[SID56463178]
Potency 0.092qHTS assay of beta-arrestin-biased ligands of beta2-adrenergic receptor: Hit Validation [AID588463, Type: confirmatory]ADRB2 gene product [Homo sapiens] [gi:4501969]
View
9
[SID56463178]
Potency 7.3078qHTS assay of beta-arrestin-biased ligands of beta2-adrenergic receptor [AID492947, Type: confirmatory]ADRB2 gene product [Homo sapiens] [gi:4501969]
View
10
[SID56463178]
Potency 7.3078qHTS assay of beta-arrestin-biased ligands of beta2-adrenergic receptor [AID492947, Type: confirmatory]ADRB2 gene product [Homo sapiens] [gi:4501969]
View
11
[SID56463178]
Potency 7.3078qHTS assay of beta-arrestin-biased ligands of beta2-adrenergic receptor [AID492947, Type: confirmatory]ADRB2 gene product [Homo sapiens] [gi:4501969]
View
12
[SID56463178]
Potency 7.3078qHTS assay of beta-arrestin-biased ligands of beta2-adrenergic receptor [AID492947, Type: confirmatory]ADRB2 gene product [Homo sapiens] [gi:4501969]
View
13
[SID56463178]
Potency 44.6684qHTS Assay for the Inhibitors of Schistosoma Mansoni Peroxiredoxins [AID485364, Type: confirmatory]thioredoxin glutathione reductase [Schistosoma mansoni] [gi:15149312]
View
14
[SID56463178]
 Counterscreen for activators of kallikrein-7 (K7) zymogen: Fluorescence intensity-based biochemical high throughput counterscreen assay for activators that optically interfere with measurement of EDANS-DABCYL fluorescence [AID686952, Type: screening]
View
15
[SID56463178]
 HTS for Beta-2AR agonists via FAP method [AID504454, Type: screening]ADRB2 gene product [Homo sapiens] [gi:4501969]
View
16
[SID56463178]
 HTS for Beta-2AR agonists via FAP method [AID504454, Type: screening]ADRB2 gene product [Homo sapiens] [gi:4501969]
View
17
[SID56463178]
 HTS for Beta-2AR agonists via FAP method [AID504454, Type: screening]ADRB2 gene product [Homo sapiens] [gi:4501969]
View
18
[SID56463178]
 HTS for Beta-2AR agonists via FAP method [AID504454, Type: screening]ADRB2 gene product [Homo sapiens] [gi:4501969]
View
19
[SID56463178]
 HTS for Beta-2AR agonists via FAP method, Single Point, Cherry Pick 1 [AID540358, Type: other]ADRB2 gene product [Homo sapiens] [gi:4501969]
View
20
[SID56463178]
 HTS for Beta-2AR agonists via FAP method, Single Point, Cherry Pick 1 [AID540358, Type: other]ADRB2 gene product [Homo sapiens] [gi:4501969]
View
21
[SID56463178]
 HTS for Beta-2AR agonists via FAP method, Single Point, Cherry Pick 1 [AID540358, Type: other]ADRB2 gene product [Homo sapiens] [gi:4501969]
View
22
[SID56463178]
 HTS for Beta-2AR agonists via FAP method, Single Point, Cherry Pick 1 [AID540358, Type: other]ADRB2 gene product [Homo sapiens] [gi:4501969]
View
23
[SID56463178]
 Re-confirmation screening for identification of compounds that activate MrgX1 receptor signaling [AID602412, Type: screening]MAS-related GPR member X1 [Homo sapiens] [gi:195969650]
View
24
[SID56463178]
 Re-confirmation screening for identification of compounds that activate MrgX1 receptor signaling [AID602412, Type: screening]MAS-related GPR member X1 [Homo sapiens] [gi:195969650]
View
25
[SID56463178]
 Fluorescence Intensity-based biochemical primary high throughput confirmation assay to identify activators of kallikrein-7 (K7) zymogen [AID686949, Type: screening]KLK7 gene product [Homo sapiens] [gi:21327705]
View
26
[SID56463178]
 Fluorescence Intensity-based biochemical primary high throughput confirmation assay to identify activators of kallikrein-7 (K7) zymogen [AID686949, Type: screening]KLK7 gene product [Homo sapiens] [gi:21327705]
View
27
[SID56463178]
 Fluorescence Intensity-based biochemical primary high throughput screening assay to identify activators of kallikrein-7 (K7) zymogen [AID652039, Type: screening]KLK7 gene product [Homo sapiens] [gi:21327705]
View
28
[SID56463178]
 Fluorescence Intensity-based biochemical primary high throughput screening assay to identify activators of kallikrein-7 (K7) zymogen [AID652039, Type: screening]KLK7 gene product [Homo sapiens] [gi:21327705]
View
29
[SID17405233]
 Modulators of the EP2 prostaglandin E2 receptor - Primary Screening [AID940, Type: screening]prostaglandin E receptor 2 (subtype EP2), 53kDa [Homo sapiens] [gi:31881630]
View
30
[SID17405233]
 Modulators of the EP2 prostaglandin E2 receptor - Primary Screening [AID940, Type: screening]prostaglandin E receptor 2 (subtype EP2), 53kDa [Homo sapiens] [gi:31881630]
View
31
[SID56463178]
 Confirmatory screen for compounds that inhibit the Choline Transporter (CHT) [AID493221, Type: screening]SLC5A7 gene product [Homo sapiens] [gi:11141885]
View
32
[SID56463178]
 Confirmatory screen for compounds that inhibit the Choline Transporter (CHT) [AID493221, Type: screening]SLC5A7 gene product [Homo sapiens] [gi:11141885]
View
33
[SID56463178]
 Primary cell-based high-throughput screening for identification of compounds that activate MrgX1 receptor signaling [AID588627, Type: screening]MAS-related GPR member X1 [Homo sapiens] [gi:195969650]
View
34
[SID56463178]
 Primary cell-based high-throughput screening for identification of compounds that activate MrgX1 receptor signaling [AID588627, Type: screening]MAS-related GPR member X1 [Homo sapiens] [gi:195969650]
View
35
[SID56463178]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
View
36
[SID56463178]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
View
37
[SID56463178]
EC50 0.372Dose response for HTS for Beta-2AR agonists via FAP method from CP1 [AID588763, Type: confirmatory]ADRB2 gene product [Homo sapiens] [gi:4501969]
View
38
[SID56463178]
EC50 0.372Dose response for HTS for Beta-2AR agonists via FAP method from CP1 [AID588763, Type: confirmatory]ADRB2 gene product [Homo sapiens] [gi:4501969]
View
39
[SID56463178]
EC50 0.372Dose response for HTS for Beta-2AR agonists via FAP method from CP1 [AID588763, Type: confirmatory]ADRB2 gene product [Homo sapiens] [gi:4501969]
View
40
[SID56463178]
EC50 0.372Dose response for HTS for Beta-2AR agonists via FAP method from CP1 [AID588763, Type: confirmatory]ADRB2 gene product [Homo sapiens] [gi:4501969]
View
41
[SID56463178]
Potency 8.9125qHTS for Inhibitors of Glutaminase (GLS) [AID624170, Type: confirmatory]GLS protein [Homo sapiens] [gi:71051501]
View
42
[SID56463178]
Potency qHTS for Antagonists of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS [AID624288, Type: confirmatory]Guanine nucleotide-binding protein G(s) subunit alpha isoforms short [gi:52000961]
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43
[SID56463178]
 Luminescence Cell-Free Homogenous Primary HTS to Identify Inhibitors of GSK-3 alpha [AID2650, Type: screening]GSK3A gene product [Homo sapiens] [gi:49574532]
View
44
[SID56463178]
 Luminescence Cell-Free Homogenous Primary HTS to Identify Inhibitors of GSK-3 alpha [AID2650, Type: screening]GSK3A gene product [Homo sapiens] [gi:49574532]
View
45
[SID56463178]
 Fluorescence-based cell-based primary high throughput screening assay to identify antagonists of the orexin 1 receptor (OX1R; HCRTR1) [AID434989, Type: screening]orexin receptor type 1 [Homo sapiens] [gi:222080095]
View
46
[SID56463178]
 Fluorescence-based cell-based primary high throughput screening assay to identify antagonists of the orexin 1 receptor (OX1R; HCRTR1) [AID434989, Type: screening]orexin receptor type 1 [Homo sapiens] [gi:222080095]
View
47
[SID56463178]
 FRET-based cell-based primary high throughput screening assay to identify antagonists of the orexin 1 receptor (OX1R; HCRTR1) [AID485270, Type: screening]orexin receptor type 1 [Homo sapiens] [gi:222080095]
View
48
[SID56463178]
 FRET-based cell-based primary high throughput screening assay to identify antagonists of the orexin 1 receptor (OX1R; HCRTR1) [AID485270, Type: screening]orexin receptor type 1 [Homo sapiens] [gi:222080095]
View
49
[SID56463178]
 Primary biochemical fluorescence polarization-based high throughput screening assay to identify inhibitors of protein arginine methyltransferase 1 (PRMT1) [AID652257, Type: screening]PRMT1 protein [Homo sapiens] [gi:32425330]
View
50
[SID56463178]
 Primary biochemical fluorescence polarization-based high throughput screening assay to identify inhibitors of protein arginine methyltransferase 1 (PRMT1) [AID652257, Type: screening]PRMT1 protein [Homo sapiens] [gi:32425330]
View