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linalool (CID 6549) - Compound BioActivity Data
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BioActivity Outcomes:
Active(20)
 
 
Inactive(842)
 
 
Inconclusive(18)
 
 
Unspecified(101)
 
 
Top Targets:
7tm 4(35)
 
 
NR LBD PPAR(26)
 
 
 
NR LBD ER(18)
 
 
NR LBD AR(18)
 
 
NR LBD TR(16)
 
 
 
BioAssay Types:
Confirmatory(463)
 
 
 
 
Screening(311)
 
 
 
Literature(107)
 
 
 
 
 
Summary(48)
 
 
BioActivity Types:
Potency(449)
 
 
 
 
IC50(10)
 
 
 
Ki(1)
 
 
EC50(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 772    Data Row: 981   Total Pages: 50   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID56462784]
DENV2 CPE-Based HTS Measured in Cell-Based and Microorganism Combination System Using Plate Reader - 2149-01_Other_SinglePoint_HTS_Activity [AID651640, Type: screening]
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2
[SID103194230]
Induction of apoptosis in Homo sapiens (human) HeLa cells assessed as fragmented nuclei at 10 to 100 ug/ml after 24 hr by acridine orange/ethidium bromide-based inverted fluorescence microscopic analysis [AID1116232, Type: other]
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3
[SID103194230]
Cytotoxicity against Homo sapiens (human) HeLa cells assessed as decrease in cell viability at 10 to 100 ug/ml after 24 hr by acridine orange/ethidium bromide-based inverted fluorescence microscopic analysis [AID1116233, Type: other]
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4
[SID103194230]
Induction of necrosis in Homo sapiens (human) HeLa cells assessed as dissolution of cytoplasmic membrane at >50 ug/ml after 24 hr by light microscopic analysis [AID1116234, Type: other]
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5
[SID103194230]
Induction of necrosis in Homo sapiens (human) HeLa cells assessed as chromatin flocculation at >50 ug/ml after 24 hr by light microscopic analysis [AID1116235, Type: other]
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6
[SID103194230]
Induction of necrosis in Homo sapiens (human) HeLa cells assessed as dissolution of nuclear membrane at >50 ug/ml after 24 hr by light microscopic analysis [AID1116236, Type: other]
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7
[SID103194230]
Induction of necrosis in Homo sapiens (human) HeLa cells assessed as increase in cytoplasmic vacuolization at >50 ug/ml after 24 hr by light microscopic analysis [AID1116237, Type: other]
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8
[SID103194230]
Induction of necrosis in Homo sapiens (human) HeLa cells assessed as increase in cytoplasmic volume at >50 ug/ml after 24 hr by light microscopic analysis [AID1116238, Type: other]
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9
[SID103194230]
Induction of necrosis in Homo sapiens (human) HeLa cells assessed as increase in nucleus volume at >50 ug/ml after 24 hr by light microscopic analysis [AID1116239, Type: other]
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10
[SID103194230]
Induction of apoptosis in Homo sapiens (human) HeLa cells assessed as apoptotic bodies at <55 ug/ml after 24 hr by light microscopic analysis [AID1116240, Type: other]
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11
[SID103194230]
Induction of apoptosis in Homo sapiens (human) HeLa cells assessed as membrane blebbing at <55 ug/ml after 24 hr by light microscopic analysis [AID1116241, Type: other]
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12
[SID103194230]
Induction of apoptosis in Homo sapiens (human) HeLa cells assessed as detachment from substratum at <55 ug/ml after 24 hr by light microscopic analysis [AID1116242, Type: other]
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13
[SID103194230]
Induction of apoptosis in Homo sapiens (human) HeLa cells assessed as loss of cell to cell contact at <55 ug/ml after 24 hr by light microscopic analysis [AID1116243, Type: other]
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14
[SID103194230]
Cytotoxicity against Homo sapiens (human) HeLa cells assessed as cell death at 10 to 100 ug/ml after 48 hr by light microscopic analysis [AID1116248, Type: other]
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15
[SID103194230]
Induction of apoptosis in Homo sapiens (human) HeLa cells assessed as rounded cells at 10 to 100 ug/ml after 48 hr by light microscopic analysis [AID1116249, Type: other]
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16
[SID103194230]
Induction of apoptosis in Homo sapiens (human) HeLa cells assessed as floating cells at 10 to 50 ug/ml after 24 hr by light microscopic analysis [AID1116250, Type: other]
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17
[SID103194230]
Induction of apoptosis in Homo sapiens (human) HeLa cells assessed as rounded cells at 10 to 50 ug/ml after 24 hr by light microscopic analysis [AID1116251, Type: other]
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18
[SID103194230]
Reversible inhibition of Electrophorus electricus (electric eel)acetylcholinesterase (AChE) using acetylthiocholine iodide substrate by Ellman method based colorimetry [AID1098340, Type: Literature]Acetylcholinesterase [gi:14916521]
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19
[SID103194230]
Competitive inhibition of Electrophorus electricus (electric eel) acetylcholinesterase (AChE) using acetylthiocholine iodide substrate by Ellman method based colorimetry [AID1098341, Type: Literature]Acetylcholinesterase [gi:14916521]
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20
[SID56462784]
uHTS Fluorescent Assay Using Nedd8 Protein Substrate for Identification of Inhibitors of Sentrin-Specific Protease 8 (SENP8) [AID602440, Type: screening]sentrin-specific protease 8 [Homo sapiens] [gi:262118306]
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