linalool (CID 6549) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(2)
 
 
Inactive(583)
 
 
Inconclusive(11)
 
 
Unspecified(35)
 
 
Top Targets:
7TM GPCR Srx(15)
 
 
NR LBD TR(10)
 
 
 
NR LBD PPAR(10)
 
 
NR LBD VDR(6)
 
 
7TM GPCR Srsx(6)
 
 
BioAssay Types:
Confirmatory(301)
 
 
 
 
Screening(262)
 
 
 
Literature(19)
 
 
 
 
BioActivity Types:
Potency(252)
 
 
 
 
IC50(10)
 
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 561    Data Row: 631   Total Pages: 13   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID56462784]
 DENV2 CPE-Based HTS Measured in Cell-Based and Microorganism Combination System Using Plate Reader - 2149-01_Other_SinglePoint_HTS_Activity [AID651640, Type: screening]
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2
[SID56462784]
 uHTS Fluorescent Assay Using Nedd8 Protein Substrate for Identification of Inhibitors of Sentrin-Specific Protease 8 (SENP8) [AID602440, Type: screening]SENP8 gene product [Homo sapiens] [gi:262118306]
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3
[SID103194230]
IC50 519Antiplasmodial activity after 48 hrs against chloroquine-resistant Plasmodium falciparum FcM29-Cameroon by [3H]hypoxanthine uptake [AID302171, Type: Literature]
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4
[SID103194230]
 Antifungal activity against Candida albicans ATCC 90028 after 48 hrs [AID302172, Type: Literature]
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5
[SID103194230]
 Antifungal activity against Candida albicans ATCC 90028 after 24 hrs [AID302173, Type: Literature]
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6
[SID103194230]
 Antimicrobial activity Propionibacterium acnes ATCC 11827 after 2 days by broth dilution method [AID332912, Type: other]
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7
[SID103194230]
 Antimicrobial activity against Bacillus subtilis ATCC 9372 after 2 days by twofold serial broth dilution method [AID334989, Type: other]
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8
[SID103194230]
 Antimicrobial activity against Brevibacterium ammoniagenes ATCC 6872 after 2 days by twofold serial broth dilution method [AID334990, Type: other]
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9
[SID103194230]
 Antimicrobial activity against Propionibacterium acnes ATCC 11827 after 2 days by twofold serial broth dilution method [AID334991, Type: other]
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10
[SID103194230]
 Antimicrobial activity against Staphylococcus aureus ATCC 12598 after 2 days by twofold serial broth dilution method [AID334992, Type: other]
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11
[SID103194230]
 Antimicrobial activity against Streptococcus mutans ATCC 25175 after 2 days by twofold serial broth dilution method [AID334993, Type: other]
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12
[SID103194230]
 Antimicrobial activity against Escherichia coli ATCC 9637 after 2 days by twofold serial broth dilution method [AID334994, Type: other]
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13
[SID103194230]
 Antimicrobial activity against Pseudomonas aeruginosa ATCC 10145 after 2 days by twofold serial broth dilution method [AID334995, Type: other]
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14
[SID103194230]
 Antimicrobial activity against Enterobacter aerogenes ATCC 13048 after 2 days by twofold serial broth dilution method [AID334996, Type: other]
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15
[SID103194230]
 Antimicrobial activity against Saccharomyces cerevisiae ATCC 7754 after 2 days by twofold serial broth dilution method [AID334997, Type: other]
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16
[SID103194230]
 Antimicrobial activity against Candida utilis ATCC 9226 after 2 days by twofold serial broth dilution method [AID334998, Type: other]
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17
[SID103194230]
 Antimicrobial activity against Pityrosporum ovale ATCC 14521 by twofold serial broth dilution method [AID334999, Type: other]
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18
[SID103194230]
 Antimicrobial activity against Penicillium chrysogenum ATCC 10106 after 5 days by twofold serial broth dilution method [AID335000, Type: other]
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19
[SID103194230]
 Acaricidal activity against Psoroptes cuniculi at 1% dilution in physiological saline after 48 hrs by direct contact assay [AID338297, Type: other]
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20
[SID103194230]
 Acaricidal activity against Psoroptes cuniculi at 0.25% dilution in physiological saline after 48 hrs by direct contact assay [AID338298, Type: other]
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21
[SID103194230]
 Acaricidal activity against Psoroptes cuniculi at 0.125% dilution in physiological saline after 48 hrs by direct contact assay [AID338299, Type: other]
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22
[SID103194230]
 Acaricidal activity against Psoroptes cuniculi at 6 uL after 24 hrs by inhalation assay [AID338300, Type: other]
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23
[SID103194230]
 Acaricidal activity against Psoroptes cuniculi at 3 uL after 24 hrs by inhalation assay [AID338301, Type: other]
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24
[SID103194230]
 Acaricidal activity against Psoroptes cuniculi at 1 uL after 24 hrs by inhalation assay [AID338302, Type: other]
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25
[SID26753091]
 qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838, Type: other]
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26
[SID103194230]
 Minimum inhibitory concentration against Propionibacterium acnes was determined [AID160385, Type: other]
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27
[SID103194230]
 Minimum inhibitory concentration against Staphylococcus aureus was determined [AID205701, Type: other]
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28
[SID103194230]
 Effect on growth in Staphylococcus aureus MN8 at 0.75 mM after 24 hrs (Rvb = 100%) [AID555331, Type: Literature]
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29
[SID103194230]
 Induction of toxin TSST-1 production in Staphylococcus aureus MN8 at 0.75 mM after 24 hrs relative to control [AID555363, Type: Literature]
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30
[SID17388947]
 qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838, Type: other]
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31
[SID103194230]
 Antimycoplasmal activity against Mycoplasma hominis PG21 after 24 to 48 hrs by broth microdilution method [AID659295, Type: Literature]
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32
[SID103194230]
 Antimycoplasmal activity against Mycoplasma fermentans Pg18 after 24 to 48 hrs by broth microdilution method [AID659296, Type: Literature]
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33
[SID103194230]
 Antimycoplasmal activity against Mycoplasma pneumoniae K7 after 3 to 5 days by broth microdilution method [AID659297, Type: Literature]
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34
[SID56462784]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
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35
[SID56462784]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
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36
[SID103194230]
 Specific activity of expressed human recombinant UGT2A1 [AID624614, Type: Literature]UDP-glucuronosyltransferase 2A1 [gi:296452854]
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37
[SID103194230]
 Specific activity of expressed human recombinant UGT1A4 [AID624608, Type: Literature]UDP-glucuronosyltransferase 1-4 [gi:136731]
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38
[SID103194230]
 Specific activity of expressed human recombinant UGT1A1 [AID624606, Type: Literature]UDP-glucuronosyltransferase 1-1 [gi:136729]
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39
[SID56462784]
Potency 89.1251HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails [AID540317, Type: confirmatory]chromobox protein homolog 1 [Homo sapiens] [gi:187960037]
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40
[SID56462784]
 uHTS identification of small molecule inhibitors of Csn-mediated Deneddylation of Cullin-Ring Ligases, vis a fluorescence polarization assay [AID651999, Type: screening]COPS5 gene product [Homo sapiens] [gi:38027923]
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41
[SID56462784]
Potency qHTS for Inhibitors of Polymerase Iota [AID588590, Type: confirmatory]DNA polymerase iota [Homo sapiens] [gi:154350220]
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42
[SID56462784]
Potency qHTS for Inhibitors of Polymerase Iota [AID588590, Type: confirmatory]DNA polymerase iota [Homo sapiens] [gi:154350220]
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43
[SID56462784]
 Activator for delta FosB/delta FosB homodimer Measured in Biochemical System Using Plate Reader - 2072-01_Activator_SinglePoint_HTS_Activity [AID493131, Type: screening]protein fosB [Mus musculus] [gi:6679827]
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44
[SID56462784]
 uHTS identification of Gli-Sufu Antagonists in a luminescence reporter assay [AID588413, Type: screening]Gli1 [Mus musculus] [gi:6009644]
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45
[SID56462784]
 uHTS identification of Gli-Sufu Antagonists in a luminescence reporter assay [AID588413, Type: screening]Gli1 [Mus musculus] [gi:6009644]
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46
[SID56462784]
 Luminescence-based cell-based primary high throughput screening assay to identify agonists of the mouse 5-hydroxytryptamine (serotonin) receptor 2A (HTR2A) [AID624169, Type: screening]Htr2a gene product [Mus musculus] [gi:27753985]
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47
[SID56462784]
 Luminescence-based cell-based primary high throughput screening assay to identify agonists of the mouse 5-hydroxytryptamine (serotonin) receptor 2A (HTR2A) [AID624169, Type: screening]Htr2a gene product [Mus musculus] [gi:27753985]
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48
[SID56462784]
Potency qHTS of IL-2 Activators [AID652025, Type: confirmatory]Il2 gene product [Mus musculus] [gi:7110653]
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49
[SID56462784]
 HTS for developing T Cell Immune Modulators [AID2052, Type: screening]integrin alpha-L [Mus musculus] [gi:124486680]
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50
[SID56462784]
 HTS for developing T Cell Immune Modulators [AID2052, Type: screening]integrin alpha-L [Mus musculus] [gi:124486680]
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