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Oxindole-Based Inhibitor 19 (CID 6539046) - Compound BioActivity Data
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BioActivity Outcomes:
Active(7)
 
 
Inactive(3)
 
 
Unspecified(456)
 
 
Top Targets:
PTKc Abl(16)
 
 
PTKc EGFR(10)
 
 
PKc like(10)
 
 
STKc MARK(8)
 
 
PTKc PDGFR al..(8)
 
 
BioAssay Types:
Literature(7)
 
 
 
BioActivity Types:
IC50(5)
 
 
AC50(2)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 466    Data Row: 466   Total Pages: 24   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103577757]
IC50 0.36Evaluated for inhibition of human cyclin dependent kinase 2 (CDK2) [AID53361, Type: Literature]
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2
[SID103577757]
IC50 0.36Inhibitory activity against human cyclin-dependent kinase 2 (CDK2) [AID53362, Type: Literature]
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3
[SID103577757]
IC50 0.36Inhibition of CDK2 [AID320938, Type: Literature]
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4
[SID103577757]
IC50 2.3Inhibition of CDK1 [AID320948, Type: Literature]
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5
[SID103577757]
IC50 2.3Inhibitory activity against human cyclin-dependent kinase 1 (CDK1) [AID55538, Type: Literature]
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6
[SID134352559]
A screen for small compounds that change glucocorticoid sensitivity in NFkB suppression [AID624486, Type: other]
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7
[SID134352559]
A screen for compounds that activate the pro-inflammatory immune response in murine macrophages [AID652131, Type: other]
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8
[SID103577757]
AC50 3.6588GSK_PKIS: Inhibition of Firefly Luciferase (Data from PubChem: AID 652016) [NIH NCATS] [AID720835, Type: Literature]Luciferin 4-monooxygenase [gi:126501]
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9
[SID103577757]
AC50 GSK_PKIS: Inhibition of Sea Pansy Luciferase (Data from PubChem: AID 652015) [NIH NCATS] [AID720834, Type: Literature]Renilla-luciferin 2-monooxygenase [gi:126502]
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10
[SID103577757]
GSK_PKIS: PDGFRB mean inhibition at 0.1 uM [Nanosyn] [AID651298, Type: other]Platelet-derived growth factor receptor beta [gi:129890]
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11
[SID103577757]
GSK_PKIS: PDGFRB mean inhibition at 1 uM [Nanosyn] [AID651299, Type: other]Platelet-derived growth factor receptor beta [gi:129890]
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12
[SID103577757]
GSK_PKIS: PDGFRA mean inhibition at 0.1 uM [Nanosyn] [AID651290, Type: other]Platelet-derived growth factor receptor alpha [gi:129892]
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13
[SID103577757]
GSK_PKIS: PDGFRA mean inhibition at 1 uM [Nanosyn] [AID651291, Type: other]Platelet-derived growth factor receptor alpha [gi:129892]
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14
[SID103577757]
GSK_PKIS: PDGFRA (D842V mutant) mean inhibition at 0.1 uM [Nanosyn] [AID651292, Type: other]Platelet-derived growth factor receptor alpha [gi:129892]
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15
[SID103577757]
GSK_PKIS: PDGFRA (D842V mutant) mean inhibition at 1 uM [Nanosyn] [AID651293, Type: other]Platelet-derived growth factor receptor alpha [gi:129892]
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16
[SID103577757]
GSK_PKIS: PDGFRA (T674I mutant) mean inhibition at 0.1 uM [Nanosyn] [AID651294, Type: other]Platelet-derived growth factor receptor alpha [gi:129892]
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17
[SID103577757]
GSK_PKIS: PDGFRA (T674I mutant) mean inhibition at 1 uM [Nanosyn] [AID651295, Type: other]Platelet-derived growth factor receptor alpha [gi:129892]
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18
[SID103577757]
GSK_PKIS: PDGFRA (V561D mutant) mean inhibition at 0.1 uM [Nanosyn] [AID651296, Type: other]Platelet-derived growth factor receptor alpha [gi:129892]
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19
[SID103577757]
GSK_PKIS: PDGFRA (V561D mutant) mean inhibition at 1 uM [Nanosyn] [AID651297, Type: other]Platelet-derived growth factor receptor alpha [gi:129892]
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20
[SID103577757]
GSK_PKIS: CDK3/cyclinE mean inhibition at 0.1 uM [Nanosyn] [AID651168, Type: other]Cyclin-dependent kinase 3 [gi:231726]
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