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BioActivity Data for Compound cadmium acetate (CID 6537495)

BioActivity Outcomes:
Active(71)
 
 
Inactive(168)
 
 
Inconclusive(180)
 
 
Unspecified(3)
 
 
Top Targets:
NR LBD PPAR(13)
 
 
 
 
NR LBD ER(9)
 
 
 
 
NR LBD AR(9)
 
 
 
 
NR LBD TR(7)
 
 
 
 
NR LBD VDR(6)
 
 
 
BioAssay Types:
Confirmatory(220)
 
 
 
 
Summary(27)
 
 
 
 
Literature(2)
 
 
BioAssay Categories:
Toxicity(36)
 
 
 
 
 
BioActivity Types:
Potency(205)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 248    Data Row: 422   Total Pages: 22   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144207253]
Potency-Replicate_1 0.0955qHTS assay for small molecules that induce genotoxicity in human embryonic kidney cells expressing luciferase-tagged ATAD5 [AID651632, Type: confirmatory]ATPase family AAA domain-containing protein 5 [gi:296439460]
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2
[SID144207253]
Ratio Potency (uM) 0.0963393qHTS assay to identify small molecule agonists of the endoplasmic reticulum stress response signaling pathway: Summary [AID1159519, Type: summary]activating transcription factor 6 [Homo sapiens] [gi:119611100]
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3
[SID144207253]
Ratio Potency (uM) 0.112323qHTS assay for small molecule activators of the heat shock response signaling pathway: Summary [AID743228, Type: summary]heat shock protein beta-1 [Homo sapiens] [gi:4504517]
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4
[SID144207253]
ATAD5 Potency (uM) 0.190563qHTS assay for small molecules that induce genotoxicity in human embryonic kidney cells expressing luciferase-tagged ATAD5: Summary [AID720516, Type: summary]ATPase family AAA domain-containing protein 5 [gi:296439460]
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5
[SID144207253]
Potency-Replicate_1 0.2138qHTS assay for small molecules that induce genotoxicity in human embryonic kidney cells expressing luciferase-tagged ATAD5 - cell viability [AID651634, Type: confirmatory]
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6
[SID144207253]
Potency-Replicate_1 0.2138qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway - cell viability counter screen [AID743203, Type: confirmatory]
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7
[SID144207253]
Potency-Replicate_1 0.2157qHTS assay to identify small molecule agonists of the endoplasmic reticulum stress response signaling pathway [AID1159516, Type: confirmatory]activating transcription factor 6 [Homo sapiens] [gi:119611100]
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8
[SID144207253]
Potency-Replicate_1 0.682qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor gamma (PPARg) signaling pathway - cell viability counter screen [AID743194, Type: confirmatory]
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9
[SID144207253]
Potency-Replicate_1 0.7653qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway - cell viability counter screen [AID743211, Type: confirmatory]
View
10
[SID17389127]
Potency 0.7943qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1) [AID2517, Type: confirmatory]Chain A, Human Ape1 Endonuclease With Bound Abasic Dna And Mn2+ Ion [gi:6980812]
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11
[SID17389127]
Potency-Replicate_1 0.8413qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway measured by Nrf2-dependant transcriptional activity [AID720636, Type: confirmatory]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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12
[SID144207253]
Antagonist Potency (uM) 1.07161qHTS assay to identify small molecule antagonists of the retinoid-related orphan receptor gamma (ROR-gamma) signaling pathway: Summary [AID1159523, Type: summary]RAR-related orphan receptor gamma [Mus musculus] [gi:15928672]
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13
[SID144207253]
Potency-Replicate_1 1.2128qHTS assay to identify small molecule antagonists of the farnesoid-X-receptor (FXR) signaling pathway - cell viability counter screen [AID743221, Type: confirmatory]
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14
[SID144207253]
Potency-Replicate_1 1.2128qHTS assay to identify small molecule agonists of the vitamin D receptor (VDR) signaling pathway - cell viability counter screen [AID743224, Type: confirmatory]
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15
[SID17389127]
Potency 1.496qHTS assay for small molecule antagonists of the retinoid-related orphan receptor gamma (ROR-gamma) signaling pathway [AID651802, Type: confirmatory]Nuclear receptor ROR-gamma [gi:49066040]
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16
[SID144207253]
Potency-Replicate_1 1.5269qHTS assay to identify small molecule agonists of the farnesoid-X-receptor (FXR) signaling pathway - cell viability counter screen [AID743218, Type: confirmatory]
View
17
[SID17389127]
Potency 1.9953qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53ts Cells at the Nonpermissive Temperature [AID902, Type: confirmatory]cellular tumor antigen p53 isoform a [Homo sapiens] [gi:120407068]
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18
[SID144207253]
Potency-Replicate_1 2.6918qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway - cell viability counter screen [AID743086, Type: confirmatory]
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19
[SID144207253]
Potency-Replicate_1 3.0202qHTS assay to identify small molecule antagonists of the retinoid-related orphan receptor gamma (ROR-gamma) signaling pathway [AID1159521, Type: confirmatory]RAR-related orphan receptor gamma [Mus musculus] [gi:15928672]
View
20
[SID144207253]
Ratio Potency (uM) 3.41825qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway: Summary [AID743063, Type: summary]AR protein [Homo sapiens] [gi:124375976]
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