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5743-04-4 (CID 6537495) - Compound BioActivity Data
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BioActivity Outcomes:
Active(67)
 
 
Inactive(166)
 
 
Inconclusive(175)
 
 
Unspecified(3)
 
 
Top Targets:
NR LBD PPAR(13)
 
 
 
 
NR LBD ER(9)
 
 
 
 
NR LBD AR(9)
 
 
 
 
NR LBD TR(7)
 
 
 
 
NR LBD VDR(6)
 
 
 
BioAssay Types:
Confirmatory(212)
 
 
 
 
Summary(24)
 
 
 
 
Literature(2)
 
 
BioActivity Types:
Potency(194)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 237    Data Row: 411   Total Pages: 21   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144207253]
Potency-Replicate_1 0.0955qHTS assay for small molecules that induce genotoxicity in human embryonic kidney cells expressing luciferase-tagged ATAD5 [AID651632, Type: confirmatory]ATPase family AAA domain-containing protein 5 [gi:296439460]
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2
[SID144207253]
Ratio Potency (uM) 0.112323qHTS assay for small molecule activators of the heat shock response signaling pathway: Summary [AID743228, Type: summary]heat shock protein beta-1 [Homo sapiens] [gi:4504517]
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3
[SID144207253]
ATAD5 Potency (uM) 0.190563qHTS assay for small molecules that induce genotoxicity in human embryonic kidney cells expressing luciferase-tagged ATAD5: Summary [AID720516, Type: summary]ATPase family AAA domain-containing protein 5 [gi:296439460]
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4
[SID144207253]
Potency-Replicate_1 0.2138qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway - cell viability counter screen [AID743203, Type: confirmatory]
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5
[SID144207253]
Potency-Replicate_1 0.2138qHTS assay for small molecules that induce genotoxicity in human embryonic kidney cells expressing luciferase-tagged ATAD5 - cell viability [AID651634, Type: confirmatory]
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6
[SID144207253]
Potency-Replicate_1 0.682qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor gamma (PPARg) signaling pathway - cell viability counter screen [AID743194, Type: confirmatory]
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7
[SID144207253]
Potency-Replicate_1 0.7653qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway - cell viability counter screen [AID743211, Type: confirmatory]
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8
[SID17389127]
Potency 0.7943qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1) [AID2517, Type: confirmatory]Chain A, Human Ape1 Endonuclease With Bound Abasic Dna And Mn2+ Ion [gi:6980812]
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9
[SID17389127]
Potency-Replicate_1 0.8413qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway measured by Nrf2-dependant transcriptional activity [AID720636, Type: confirmatory]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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10
[SID144207253]
Potency-Replicate_1 1.2128qHTS assay to identify small molecule antagonists of the farnesoid-X-receptor (FXR) signaling pathway - cell viability counter screen [AID743221, Type: confirmatory]
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11
[SID144207253]
Potency-Replicate_1 1.2128qHTS assay to identify small molecule agonists of the vitamin D receptor (VDR) signaling pathway - cell viability counter screen [AID743224, Type: confirmatory]
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12
[SID17389127]
Potency 1.496qHTS assay for small molecule antagonists of the retinoid-related orphan receptor gamma (ROR-gamma) signaling pathway [AID651802, Type: confirmatory]Nuclear receptor ROR-gamma [gi:49066040]
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13
[SID144207253]
Potency-Replicate_1 1.5269qHTS assay to identify small molecule agonists of the farnesoid-X-receptor (FXR) signaling pathway - cell viability counter screen [AID743218, Type: confirmatory]
View
14
[SID17389127]
Potency 1.9953qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53ts Cells at the Nonpermissive Temperature [AID902, Type: confirmatory]cellular tumor antigen p53 isoform a [Homo sapiens] [gi:120407068]
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15
[SID144207253]
Potency-Replicate_1 2.6918qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway - cell viability counter screen [AID743086, Type: confirmatory]
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16
[SID144207253]
Ratio Potency (uM) 3.41825qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway: Summary [AID743063, Type: summary]AR protein [Homo sapiens] [gi:124375976]
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17
[SID17389127]
Potency 7.5123qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1) [AID1030, Type: confirmatory]aldehyde dehydrogenase 1 family, member A1 [Homo sapiens] [gi:30582681]
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18
[SID144207253]
Potency-Replicate_1 7.6525qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway [AID743035, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
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19
[SID17389127]
Potency-Replicate_1 8.4127qHTS assay for small molecule antagonists of the retinoid-related orphan receptor gamma (ROR-gamma) signaling pathway - cell viability counter screen [AID720652, Type: confirmatory]
View
20
[SID144207253]
Ratio Potency (uM) 9.62916qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway: Summary [AID743077, Type: summary]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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