7H-purine-6-thiol hydrate (CID 6537489) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(44)
 
 
Inactive(230)
 
 
Inconclusive(128)
 
 
Unspecified(4)
 
 
Top Targets:
globin(5)
 
 
 
NR LBD PPAR(5)
 
 
 
NR LBD TR(4)
 
 
 
P53(3)
 
 
 
 
NR LBD VDR(3)
 
 
 
BioAssay Types:
Confirmatory(170)
 
 
 
 
Literature(63)
 
 
 
 
 
BioActivity Types:
Potency(134)
 
 
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 175    Data Row: 406   Total Pages: 9   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID17389218]
Potency 0.1995Confirmation and Secondary Assay for Modulators of Hemoglobin Beta Chain Splicing at IVS2 654 locus: Cytotoxicity [AID931, Type: confirmatory]hemoglobin subunit beta [Homo sapiens] [gi:4504349]
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2
[SID17389218]
Potency 1.58489Confirmation and Secondary Assays for Modulators of Hemoglobin Beta Chain Splicing at IVS2 654 and 705 loci [AID1405, Type: confirmatory]hemoglobin subunit beta [Homo sapiens] [gi:4504349]
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3
[SID17389218]
Potency 1.5849Cell Viability - LYMP1-003 - Assay at 40 hr [AID964, Type: confirmatory]
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4
[SID17389218]
Potency 2.2387qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1) [AID1030, Type: confirmatory]aldehyde dehydrogenase 1 family, member A1 [Homo sapiens] [gi:30582681]
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5
[SID17389218]
Potency 2.2387qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1) [AID1030, Type: confirmatory]aldehyde dehydrogenase 1 family, member A1 [Homo sapiens] [gi:30582681]
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6
[SID17389218]
Potency 2.8695S16 Schwann cell PMP22 intronic element firefly luciferase assay [AID624032, Type: confirmatory]Pmp22 gene product [Rattus norvegicus] [gi:8393992]
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7
[SID17389218]
Potency 3.1623Confirmation and Secondary Assay for Modulators of Hemoglobin Beta Chain Splicing at IVS2 654 locus [AID910, Type: confirmatory]hemoglobin subunit beta [Homo sapiens] [gi:4504349]
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8
[SID17389218]
Potency 3.1623Confirmation and Secondary Assay for Modulators of Hemoglobin Beta Chain Splicing at IVS2 705 locus [AID930, Type: confirmatory]hemoglobin subunit beta [Homo sapiens] [gi:4504349]
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9
[SID17389218]
Potency 10qHTS assay for small molecule activators of the p53 signaling pathway [AID651743, Type: confirmatory]Cellular tumor antigen p53 [gi:269849759]
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10
[SID17389218]
Potency 10qHTS assay for small molecule activators of the p53 signaling pathway [AID651743, Type: confirmatory]Cellular tumor antigen p53 [gi:269849759]
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11
[SID17389218]
Potency 10qHTS assay for small molecule activators of the p53 signaling pathway [AID651743, Type: confirmatory]Cellular tumor antigen p53 [gi:269849759]
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12
[SID17389218]
Potency 10qHTS assay for small molecule activators of the p53 signaling pathway [AID651743, Type: confirmatory]Cellular tumor antigen p53 [gi:269849759]
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13
[SID17389218]
Potency 14.1254qHTS Assay for Inhibitors of Bacillus subtilis Sfp phosphopantetheinyl transferase (PPTase) [AID1490, Type: confirmatory]phosphopantetheinyl transferase [Bacillus subtilis] [gi:10954339]
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14
[SID17389218]
Potency 14.1254qHTS Assay for Inhibitors of Tyrosyl-DNA Phosphodiesterase (TDP1) [AID485290, Type: confirmatory]Chain A, Crystal Structure Of Human Tyrosyl-Dna Phosphodiesterase (Tdp1) [gi:20150581]
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15
[SID17389218]
Potency 17.7693S16 Schwann cell PMP22 intronic element beta-lactamase assay [AID624044, Type: confirmatory]Pmp22 gene product [Rattus norvegicus] [gi:8393992]
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16
[SID17389218]
Potency 22.3872qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a [AID504332, Type: confirmatory]euchromatic histone-lysine N-methyltransferase 2 [Homo sapiens] [gi:168985070]
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17
[SID17389218]
Potency 23.7101qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway [AID651741, Type: confirmatory]NFE2L2 gene product [Homo sapiens] [gi:20149576]
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18
[SID17389218]
Potency 23.7101qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway [AID651741, Type: confirmatory]NFE2L2 gene product [Homo sapiens] [gi:20149576]
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19
[SID17389218]
Potency 23.7101qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway [AID651741, Type: confirmatory]NFE2L2 gene product [Homo sapiens] [gi:20149576]
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20
[SID17389218]
Potency 23.7101qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway [AID651741, Type: confirmatory]NFE2L2 gene product [Homo sapiens] [gi:20149576]
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21
[SID17389218]
Potency 42.1632qHTS assay to identify small molecules that stimulate interleukin-8 (IL-8) secretion [AID651758, Type: confirmatory]interleukin 8 [Homo sapiens] [gi:186368]
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22
[SID17389218]
Potency 42.1632qHTS assay to identify small molecules that stimulate interleukin-8 (IL-8) secretion [AID651758, Type: confirmatory]interleukin 8 [Homo sapiens] [gi:186368]
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23
[SID17389218]
Potency 42.1632qHTS assay to identify small molecules that stimulate interleukin-8 (IL-8) secretion [AID651758, Type: confirmatory]interleukin 8 [Homo sapiens] [gi:186368]
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24
[SID17389218]
 Cell Viability - SK-N-SH [AID435, Type: confirmatory]
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25
[SID17389218]
 Cell Viability - Hek293 [AID427, Type: confirmatory]
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26
[SID17389218]
 Cell Viability - Jurkat [AID426, Type: confirmatory]
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27
[SID17389218]
 Cell Viability - BJ [AID421, Type: confirmatory]
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28
[SID17389218]
 Cell Viability - NIH 3T3 [AID541, Type: confirmatory]
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29
[SID17389218]
 Cell Viability - H-4-II-E [AID543, Type: confirmatory]
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30
[SID17389218]
 Cell Viability - Mesenchymal [AID546, Type: confirmatory]
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31
[SID17389218]
 Cell Viability - HepG2 [AID433, Type: confirmatory]
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32
[SID17389218]
 qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_30, Type: Literature]
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33
[SID17389218]
 Cell Viability Profiling of Human Lymphoblast Cell Lines [AID588812_8, Type: other]
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34
[SID17389218]
 Cell Viability Profiling of Human Lymphoblast Cell Lines [AID588812_11, Type: other]
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35
[SID17389218]
 Cell Viability Profiling of Human Lymphoblast Cell Lines [AID588812_12, Type: other]
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36
[SID17389218]
 Cell Viability Profiling of Human Lymphoblast Cell Lines [AID588812_14, Type: other]
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37
[SID17389218]
 Cell Viability Profiling of Human Lymphoblast Cell Lines [AID588812_19, Type: other]
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38
[SID17389218]
 Cell Viability Profiling of Human Lymphoblast Cell Lines [AID588812_20, Type: other]
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39
[SID17389218]
 Cell Viability Profiling of Human Lymphoblast Cell Lines [AID588812_23, Type: other]
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40
[SID17389218]
 Cell Viability Profiling of Human Lymphoblast Cell Lines [AID588812_31, Type: other]
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41
[SID17389218]
 Cell Viability Profiling of Human Lymphoblast Cell Lines [AID588812_29, Type: other]
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42
[SID17389218]
 Cell Viability Profiling of Human Lymphoblast Cell Lines [AID588812_36, Type: other]
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43
[SID17389218]
 Cell Viability Profiling of Human Lymphoblast Cell Lines [AID588812_54, Type: other]
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44
[SID17389218]
 Cell Viability Profiling of Human Lymphoblast Cell Lines [AID588812_64, Type: other]
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45
[SID17389218]
 Cell Viability Profiling of Human Lymphoblast Cell Lines [AID588812_69, Type: other]
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46
[SID17389218]
 Cell Viability Profiling of Human Lymphoblast Cell Lines [AID588812_46, Type: other]
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47
[SID17389218]
 Cell Viability Profiling of Human Lymphoblast Cell Lines [AID588812_73, Type: other]
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48
[SID17389218]
 Cell Viability Profiling of Human Lymphoblast Cell Lines [AID588812_75, Type: other]
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49
[SID17389218]
 Cell Viability Profiling of Human Lymphoblast Cell Lines [AID588812_76, Type: other]
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50
[SID17389218]
 Cell Viability Profiling of Human Lymphoblast Cell Lines [AID588812_80, Type: other]
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