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7H-purine-6-thiol hydrate (CID 6537489) - Compound BioActivity Data
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BioActivity Outcomes:
Active(61)
 
 
Inactive(282)
 
 
Inconclusive(157)
 
 
Unspecified(4)
 
 
Top Targets:
NR LBD PPAR(13)
 
 
 
NR LBD ER(9)
 
 
 
NR LBD AR(9)
 
 
 
NR LBD TR(7)
 
 
 
NR LBD VDR(7)
 
 
 
BioAssay Types:
Confirmatory(243)
 
 
 
 
Literature(64)
 
 
 
 
 
Summary(24)
 
 
 
 
BioActivity Types:
Potency(225)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 267    Data Row: 504   Total Pages: 26   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID17389218]
Potency 0.1995Confirmation and Secondary Assay for Modulators of Hemoglobin Beta Chain Splicing at IVS2 654 locus: Cytotoxicity [AID931, Type: confirmatory]hemoglobin subunit beta [Homo sapiens] [gi:4504349]
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2
[SID144208192]
Potency-Replicate_1 0.5448qHTS assay for small molecule agonists of the p53 signaling pathway - cell viability [AID651633, Type: confirmatory]
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3
[SID17389218]
Potency 1.58489Confirmation and Secondary Assays for Modulators of Hemoglobin Beta Chain Splicing at IVS2 654 and 705 loci [AID1405, Type: confirmatory]hemoglobin subunit beta [Homo sapiens] [gi:4504349]
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4
[SID17389218]
Potency 1.5849Cell Viability - LYMP1-003 - Assay at 40 hr [AID964, Type: confirmatory]
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5
[SID17389218]
Potency 2.2387qHTS assay for cell viability of HEK293 cells [AID743288, Type: confirmatory]
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6
[SID17389218]
Potency 2.2387qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1) [AID1030, Type: confirmatory]aldehyde dehydrogenase 1 family, member A1 [Homo sapiens] [gi:30582681]
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7
[SID17389218]
Potency 2.8695S16 Schwann cell PMP22 intronic element firefly luciferase assay [AID624032, Type: confirmatory]peripheral myelin protein 22 [Rattus norvegicus] [gi:8393992]
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8
[SID144208192]
Potency-Replicate_1 3.0918qHTS assay to identify small molecule agonists of the vitamin D receptor (VDR) signaling pathway - cell viability counter screen [AID743224, Type: confirmatory]
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9
[SID17389218]
Potency 3.1623Confirmation and Secondary Assay for Modulators of Hemoglobin Beta Chain Splicing at IVS2 705 locus [AID930, Type: confirmatory]hemoglobin subunit beta [Homo sapiens] [gi:4504349]
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10
[SID17389218]
Potency 3.1623Confirmation and Secondary Assay for Modulators of Hemoglobin Beta Chain Splicing at IVS2 654 locus [AID910, Type: confirmatory]hemoglobin subunit beta [Homo sapiens] [gi:4504349]
View
11
[SID144208192]
Ratio Potency (uM) 3.18365qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway: Summary [AID743219, Type: summary]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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12
[SID144208192]
Potency-Replicate_1 3.4376qHTS assay for small molecule agonists of the p53 signaling pathway [AID651631, Type: confirmatory]Cellular tumor antigen p53 [gi:269849759]
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13
[SID144208192]
Ratio Potency (uM) 4.85577qHTS assay for small molecule disruptors of the mitochondrial membrane potential: Summary [AID720637, Type: summary]
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14
[SID144208192]
Potency-Replicate_1 4.8558qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
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15
[SID144208192]
Potency-Replicate_1 4.8558qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway [AID743202, Type: confirmatory]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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16
[SID144208192]
Ratio Potency (uM) 5.66142qHTS assay for small molecule agonists of the p53 signaling pathway: Summary [AID720552, Type: summary]Cellular tumor antigen p53 [gi:269849759]
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17
[SID144208192]
Potency-Replicate_1 7.7663qHTS assay to identify small molecule antagonists of the vitamin D receptor (VDR) signaling pathway - cell viability counter screen [AID743225, Type: confirmatory]
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18
[SID144208192]
Potency-Replicate_1 8.6349qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway - cell viability counter screen [AID743203, Type: confirmatory]
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19
[SID17389218]
Potency 10qHTS assay for small molecule activators of the p53 signaling pathway [AID651743, Type: confirmatory]Cellular tumor antigen p53 [gi:269849759]
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20
[SID144208192]
Potency-Replicate_1 10.9702qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway - cell viability counter screen [AID743074, Type: confirmatory]
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