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hexamidine (CID 65130) - Compound BioActivity Data
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BioActivity Outcomes:
Active(3)
 
 
Inactive(3)
 
 
Unspecified(6)
 
 
BioAssay Types:
Literature(12)
 
 
 
 
BioActivity Types:
Ki(3)
 
 
IC50(3)
 
 
 
Kd(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 12    Data Row: 12   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103190118]
Ki 0.224compound was tested for inhibitory activity against Thrombin [AID211360, Type: Literature]
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2
[SID103190118]
Ki 0.924compound was tested for inhibitory activity against Matriptase [AID108587, Type: Literature]
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3
[SID103190118]
Ki 14.4compound was tested for inhibitory activity against Urokinase-type plasminogen activator (microPa) [AID228651, Type: Literature]
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4
[SID103190118]
IC50 396.278Inhibition on leishmania mexicana amazonensis. [AID101036, Type: Literature]
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5
[SID103190118]
Denaturation temperature change on binding to AT to poly (dA)-poly(dT) [AID54423, Type: Literature]
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6
[SID103190118]
Denaturation temperature change on binding on GC to poly(dGC)-poly(dGC) [AID54424, Type: Literature]
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7
[SID103190118]
DNA binding property estimated by measuring denaturation temperature on GC to poly (dGC)-poly(dGC), normalized to ethidium bromide [AID54425, Type: Literature]
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8
[SID103190118]
Denaturation temperature change on binding to calf thymus DNA [AID54426, Type: Literature]
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9
[SID103190118]
DNA binding activity as denaturation temperatures on AT to poly (dA)-poly(dT) normalized to ethidium bromide [AID54427, Type: Literature]
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10
[SID103190118]
Kd Binding affinity to rat/bovine recombinant S100B expressed in Escherichia coli [HMS174(DE3)strain] by NMR spectroscopy [AID712198, Type: Literature]
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11
[SID103190118]
IC50 Growth inhibition of human MALME-3M cells transfected with S100B siRNA after 4 days by SYBR green assay [AID712267, Type: Literature]
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12
[SID103190118]
IC50 Growth inhibition of human MALME-3M cells overexpressing calcium-binding protein S100B after 4 days by SYBR green assay [AID712268, Type: Literature]
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