hexamidine (CID 65130) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(3)
 
 
Unspecified(6)
 
 
BioAssay Types:
Literature(9)
 
 
 
BioActivity Types:
Ki(3)
 
 
IC50(1)
 
 
SAR
Target summary
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 9    Data Row: 9   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103190118]
Ki 0.224compound was tested for inhibitory activity against Thrombin [AID211360, Type: Literature]
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2
[SID103190118]
Ki 0.924compound was tested for inhibitory activity against Matriptase [AID108587, Type: Literature]
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3
[SID103190118]
Ki 14.4compound was tested for inhibitory activity against Urokinase-type plasminogen activator (microPa) [AID228651, Type: Literature]
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4
[SID103190118]
IC50 396.278Inhibition on leishmania mexicana amazonensis. [AID101036, Type: Literature]
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5
[SID103190118]
 Denaturation temperature change on binding to AT to poly (dA)-poly(dT) [AID54423, Type: Literature]
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6
[SID103190118]
 Denaturation temperature change on binding on GC to poly(dGC)-poly(dGC) [AID54424, Type: Literature]
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7
[SID103190118]
 DNA binding property estimated by measuring denaturation temperature on GC to poly (dGC)-poly(dGC), normalized to ethidium bromide [AID54425, Type: Literature]
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8
[SID103190118]
 Denaturation temperature change on binding to calf thymus DNA [AID54426, Type: Literature]
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9
[SID103190118]
 DNA binding activity as denaturation temperatures on AT to poly (dA)-poly(dT) normalized to ethidium bromide [AID54427, Type: Literature]
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