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BioActivity Data for Compound 2'-deoxycytidine 5'-triphosphate (CID 65091)

BioActivity Outcomes:
Active(8)
 
 
Unspecified(14)
 
 
Top Targets:
P-loop NTPase(1)
 
 
dNK(1)
 
 
BioAssay Types:
Literature(22)
 
 
 
BioAssay Categories:
Biochemical(19)
 
 
 
ADME(3)
 
 
 
Cell-based(1)
 
 
BioActivity Types:
Kd(6)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 22    Data Row: 22   Total Pages: 2   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103685220]
Kd 1.1Binding affinity to HIV1 reverse transcriptase [AID572771, Type: Literature]
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2
[SID103685220]
Kd 1.14Binding affinity to wild type HIV1 LAI reverse transcriptase [AID432585, Type: Literature]
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3
[SID103685220]
Kd 1.23Binding affinity to HIV1 LAI reverse transcriptase M41L/L210W/T215Y mutant [AID432587, Type: Literature]
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4
[SID103685220]
Kd 2.49Binding affinity to HIV1 LAI reverse transcriptase M184V mutant [AID432586, Type: Literature]
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5
[SID103685220]
Kd 2.51Binding affinity to HIV1 LAI reverse transcriptase M41L/L210W/T215Y/M184V/G333D mutant [AID432589, Type: Literature]
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6
[SID103685220]
Kd 2.99Binding affinity to HIV1 LAI reverse transcriptase M41L/L210W/T215Y/M184V mutant [AID432588, Type: Literature]
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7
[SID103685220]
Km 3.74Activity of HIV1 reverse transcriptase [AID711539, Type: Literature]
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8
[SID103685220]
Km 25.6Kinetic parameter Km was determined [AID18096, Type: Literature]
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9
[SID103685220]
Ratio of Kpol to Kd for HIV1 LAI reverse transcriptase M41L/L210W/T215Y/M184V/G333D mutant [AID432619, Type: Literature]
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10
[SID103685220]
Ratio of Kpol to Kd for HIV1 LAI reverse transcriptase M41L/L210W/T215Y/M184V mutant [AID432618, Type: Literature]
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11
[SID103685220]
Ratio of Kpol to Kd for HIV1 LAI reverse transcriptase M41L/L210W/T215Y mutant [AID432617, Type: Literature]
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12
[SID103685220]
Ratio of Kpol to Kd for HIV1 LAI reverse transcriptase M184V mutant [AID432616, Type: Literature]
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13
[SID103685220]
Ratio of Kpol to Kd for wild type HIV1 LAI reverse transcriptase [AID432615, Type: Literature]
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14
[SID103685220]
Ratio of Vmax to Km for HIV1 reverse transcriptase [AID711538, Type: Literature]
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15
[SID103685220]
Activity of HIV1 reverse transcriptase assessed per unit of protein [AID711522, Type: Literature]
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16
[SID103685220]
Inhibition of thymidine kinase in BHK21 (C13) cells using [14C]thymidine after 10 mins by liquid scintillation spectrometer analysis relative to control in presence of Mg2+ [AID1124516, Type: Literature]Thymidine kinase, cytosolic [gi:125428]
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17
[SID103685220]
Inhibition of human cytoplasmic thymidine kinase using [14C]thymidine after 10 mins by liquid scintillation spectrometer analysis relative to control in presence of Mg2+ [AID1124511, Type: Literature]Thymidine kinase, cytosolic [gi:23503074]
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18
[SID103685220]
Inhibition of human mitochondrial thymidine kinase using [14C]thymidine after 10 mins by liquid scintillation spectrometer analysis relative to control in presence of Mg2+ [AID1124519, Type: Literature]Thymidine kinase 2, mitochondrial [gi:254763443]
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19
[SID103685220]
Efficiency expressed as ratio of Vmax to that of Km was determined [AID229453, Type: Literature]
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20
[SID103685220]
Activity at HIV1 reverse transcriptase measured after 30 mins [AID572770, Type: Literature]
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