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3',6'-diacetylfluorescein (CID 65047) - Compound BioActivity Data
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BioActivity Outcomes:
Active(131)
 
 
Inactive(509)
 
 
Inconclusive(46)
 
 
Unspecified(2)
 
 
Top Targets:
7tm 4(43)
 
 
 
 
Bcl-2 like(13)
 
 
 
 
alkPPc(10)
 
 
G-alpha(9)
 
 
 
 
Esterase lipa..(9)
 
 
 
BioAssay Types:
Screening(416)
 
 
 
 
Confirmatory(227)
 
 
 
 
 
Literature(12)
 
 
 
Summary(1)
 
 
BioActivity Types:
Potency(155)
 
 
 
 
 
IC50(44)
 
 
 
 
EC50(16)
 
 
 
AC50(4)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 614    Data Row: 688   Total Pages: 35   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID17514836]
Potency 0.0225qHTS Fluorescence Polarization (FP) Assay for Inhibitors of MLL CXXC domain - DNA interaction: Fluorescein FP [AID624160, Type: confirmatory]
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2
[SID17514836]
AC50_uM 0.042C-LANA FP assay Measured in Biochemical System Using Plate Reader - 2117-01_Inhibitor_Dose_CherryPick_Activity [AID504725, Type: confirmatory]LANA [Human herpesvirus 8] [gi:312275222]
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3
[SID17514836]
EC50_uM 0.06Fluorescence Polarization Cell-Free Homogeneous Dose Retest to Confirm Inhibitors of the LANA Histone H2A/H2B Interaction [AID435023, Type: confirmatory]LANA [Human herpesvirus 8] [gi:139472804]
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4
[SID17514836]
Potency 0.3162qHTS Multiplex Assay to Identify Dual Action Probes in a Cell Model of Huntington: Aggregate Formation (GFP) [AID1688, Type: confirmatory]huntingtin [Homo sapiens] [gi:90903231]
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5
[SID17514836]
Absolute IC50 0.42Dose Response Confirmation for Small Molecule Inhibitors of Epstein-Barr Virus [AID1419, Type: confirmatory]BZLF2 [Human herpesvirus 4 type 2] [gi:139424501]
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6
[SID17514836]
EC50 0.439HCS for Compounds that Up-Regulate Insulin Promoter Activity in MIN6 Cells [AID1625, Type: confirmatory]
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7
[SID17514836]
EC50_MICROM 1.512Profiling Assay to determine GST-GSH interactions in multiplex bead-based assays [AID1769, Type: confirmatory]glutathione S-transferase, partial [Homo sapiens] [gi:31933]
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8
[SID17514836]
Potency 6.7016qHTS for Inhibitors of PLK1-PDB (polo-like kinase 1 - polo-box domain): Primary Screen [AID720504, Type: confirmatory]serine/threonine-protein kinase PLK1 [Homo sapiens] [gi:21359873]
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9
[SID17514836]
AC50_uM 8.389C-LANA Counter Screen: DNA intercalators Measured in Biochemical System Using Plate Reader - 2117-02_Inhibitor_Dose_CherryPick_Activity_Set2 [AID504727, Type: confirmatory]LANA [Human herpesvirus 8] [gi:312275222]
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10
[SID17514836]
Potency 39.8107qHTS for Antagonist of cAMP-regulated guanine nucleotide exchange factor 2 (EPAC2): primary screen [AID720708, Type: confirmatory]Rap guanine nucleotide exchange factor 4 [gi:32171491]
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11
[SID17514836]
Multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions. [AID1504, Type: summary]GNAO1 protein [Homo sapiens] [gi:34190601]
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12
[SID17514836]
Primary cell-based high-throughput screening assay to identify agonists of the transient receptor potential channel N1 (TRPN1) [AID1424, Type: screening]transient receptor potential cation channel, subfamily N, member 1 [Danio rerio] [gi:34330186]
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13
[SID17514836]
Primary cell-based high-throughput screening assay to identify agonists of the transient receptor potential channel ML3 (TRPML3) [AID1448, Type: screening]MCOLN3 protein [Homo sapiens] [gi:38174238]
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14
[SID17514836]
uHTS identification of agonists of the CRF-binding protein and CRF-R2 receptor complex [AID588473, Type: screening]corticotropin-releasing hormone receptor 2 [Homo sapiens] [gi:38349113]
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15
[SID17514836]
Fluorescence-based cell-based primary high throughput screening assay to identify agonists of the human cholinergic receptor, muscarinic 1 (CHRM1) [AID588814, Type: screening]muscarinic acetylcholine receptor M1 [Homo sapiens] [gi:37622910]
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16
[SID17514836]
Fluorescence-based cell-based primary high throughput screening assay to identify antagonists of the human M1 muscarinic receptor (CHRM1) [AID588852, Type: screening]muscarinic acetylcholine receptor M1 [Homo sapiens] [gi:37622910]
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17
[SID17514836]
High-throughput multiplex screening for ABC transporter inhibitors: specifically ABCB1 screen, ABCG2 counter-screen [AID1326, Type: screening]multidrug resistance protein 1 [Homo sapiens] [gi:42741659]
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18
[SID17514836]
Fluorescence polarization to screen for inhibitors that disrupt the protein-protein interaction between Keap1 and Nrf2 Measured in Biochemical System Using Plate Reader - 2119-01_Inhibitor_SinglePoint_HTS_Activity [AID504523, Type: screening]kelch-like ECH-associated protein 1 [Homo sapiens] [gi:45269145]
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19
[SID17514836]
Fluorescence-based biochemical high throughput confirmation assay for activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF) [AID504383, Type: screening]troponin T, cardiac muscle isoform 3 [Homo sapiens] [gi:48255881]
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20
[SID17514836]
Fluorescence-based biochemical primary high throughput screening assay to identify activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF) [AID493008, Type: screening]troponin T, cardiac muscle isoform 3 [Homo sapiens] [gi:48255881]
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