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emivirine (CID 65013) - Compound BioActivity Data
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BioActivity Outcomes:
Active(59)
 
 
Inconclusive(7)
 
 
Unspecified(46)
 
 
BioAssay Types:
Literature(112)
 
 
 
 
BioActivity Types:
IC50(39)
 
 
 
EC50(28)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 111    Data Row: 112   Total Pages: 6   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103209563]
EC50 0.001Compound was tested for its inhibition of HIV-1 induced focus formation in MAGI-CCR5 cells in strains like NL4-3 [AID102401, Type: Literature]
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2
[SID103209563]
EC50 0.002Effective concentration required against wild type HIV-1 reverse transcriptase [AID199996, Type: Literature]
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3
[SID103209563]
EC50 0.003The effective concentration required to achieve 50% protection of MT-4 cells against the cytopathic effect of HIV-1 virus A012D strain [AID105514, Type: Literature]
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4
[SID103209563]
EC50 0.004Inhibition of HIV-1 reverse transcriptase at 37 degree Centigrade [AID200003, Type: Literature]
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5
[SID103209563]
EC50 0.004Compound was tested for its inhibition of HIV-1 induced focus formation in MAGI-CCR5 cells in strains like IIIB [AID102399, Type: Literature]
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6
[SID103209563]
IC50 0.004Inhibitory activity of compound on p24 production in peripheral blood mononuclear cells infected with HIV strain HTLV IIIB wild type. [AID152661, Type: Literature]
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7
[SID103209563]
IC50 0.004Ability to inhibit the replication of HTLV IIIb strain of HIV-1 p24 antigen production in PBMC [AID155272, Type: Literature]
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8
[SID103209563]
IC50 0.004Anti-HIV activity by its ability to inhibit the replication of HIV-1 strain HTLV IIIB in peripheral blood mononuclear cells (PBMC) [AID155278, Type: Literature]
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9
[SID103209563]
IC50 0.004Compound was evaluated for inhibition of p24 production in HIV infected peripheral blood mononuclear cells [AID155289, Type: Literature]
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10
[SID103209563]
EC50 0.004The effective concentration required to achieve 50% protection of human peripheral blood lymphocytes against the cytopathic effect of HIV-1 virus HTLV-IIIB strain [AID157405, Type: Literature]
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11
[SID103209563]
EC50 0.0042Effective concentration required to achieve 50% protection of MT-4 cells against the cytopathic effect of HIV-1 virus. [AID105513, Type: Literature]
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12
[SID103209563]
EC50 0.0042Inhibitory concentration against HIV-1 reverse transcriptase [AID200009, Type: Literature]Reverse transcriptase/RNaseH [gi:82310930]
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13
[SID103209563]
ED50 0.005Effective dose required for 50% inhibition of HIV-1 antigen production in MT-4 cultures [AID104311, Type: Literature]
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14
[SID103209563]
ED50 0.005Effective dose of compound required to inhibit 50% of HIV-1 antigen production in MT-4 cultures. [AID105530, Type: Literature]
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15
[SID46393106]
IC50 0.008Experimentally measured binding affinity data (IC50) for protein-ligand complexes derived from PDB [AID977608, Type: Literature]Chain A, Crystal Structure Of Hiv-1 Reverse Transcriptase Complexed With Mkc-442 [gi:2098306]
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16
[SID46393106]
IC50 0.008Experimentally measured binding affinity data (IC50) for protein-ligand complexes derived from PDB [AID977608, Type: Literature]Chain A, Crystal Structure Of Hiv-1 Reverse Transcriptase Complexed With Mkc-442 [gi:2098306]
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17
[SID103209563]
IC50 0.008Inhibitory activity against HIV-1 reverse transcriptase [AID198238, Type: Literature]
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18
[SID103209563]
IC50 0.008Inhibitory activity against wild type HIV-1 LAI cell line [AID247526, Type: Literature]
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19
[SID103209563]
IC50 0.008Concentration required to inhibit 50% viral production of human immunodeficiency virus type 1 (HIV-1-IIIB) [AID248354, Type: Literature]
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20
[SID103209563]
IC50 0.008Anti-HIV-1 activity against LAI strain in MT-4 cells by the MTT method [AID105701, Type: Literature]
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