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ST50738465 (CID 6484377) - Compound BioActivity Data
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BioActivity Outcomes:
Active(66)
 
 
Inactive(585)
 
 
Inconclusive(19)
 
 
Unspecified(2)
 
 
Top Targets:
7TM GPCR Srx(23)
 
 
alkPPc(17)
 
 
 
7TM GPCR Srsx(15)
 
 
Bcl-2 like(11)
 
 
Peptidase C48(8)
 
 
 
BioAssay Types:
Screening(421)
 
 
 
 
Confirmatory(217)
 
 
 
 
 
Literature(13)
 
 
Summary(1)
 
 
BioActivity Types:
Potency(156)
 
 
 
 
 
IC50(38)
 
 
EC50(12)
 
 
 
AC50(5)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 609    Data Row: 672   Total Pages: 34   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID24784938]
Potency 0.9268qHTS of small molecules that selectively kill Giardia lamblia: Hit Validation in HepG2 cytotox [AID588382, Type: confirmatory]
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2
[SID24784938]
Potency 1.4125qHTS Assay for Rab9 Promoter Activators [AID485297, Type: confirmatory]ras-related protein Rab-9A [Homo sapiens] [gi:4759012]
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3
[SID24784938]
Potency 1.5849Counterscreen for Luciferase (Kinase-Glo TM) Inhibition [AID1379, Type: confirmatory]luciferase [Photuris pennsylvanica] [gi:1669525]
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4
[SID24784938]
Potency 1.5849qHTS for Inhibitors of TGF-b: Cytotox Counterscreen [AID588856, Type: confirmatory]
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5
[SID24784938]
Potency 1.7783qHTS Assay for NPC1 Promoter Activators [AID485313, Type: confirmatory]Niemann-Pick C1 protein precursor [Homo sapiens] [gi:255652944]
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6
[SID24784938]
Potency 2.1331qHTS profiling assay for firefly luciferase inhibitor/activator using purifed enzyme and Km concentrations of substrates (counterscreen for miR-21 project) [AID588342, Type: confirmatory]Luciferase [Photinus pyralis] [gi:160794]
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7
[SID24784938]
AC50_uM 2.228Anti-Malarial Hsp90 Inhibitors Measured in Microorganism System Using Plate Reader - 2121-01_Inhibitor_Dose_CherryPick_Activity [AID540268, Type: confirmatory]HSP90 [Plasmodium falciparum 3D7] [gi:124809506]
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8
[SID24784938]
Potency 2.3086Confirmation Concentration-Response Assay for Inhibitors of Human Muscle isoform 2 Pyruvate Kinase [AID2263, Type: confirmatory]pyruvate kinase PKM isoform a [Homo sapiens] [gi:33286418]
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9
[SID24784938]
AC50_uM 2.482Luminescence Cell-Based Dose Retest to Confirm Inhibitors of Beta Cell Apoptosis [AID449756, Type: confirmatory]
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10
[SID24784938]
AC50_uM 2.897ATP-based Luminescence in the Absence of Cytokines Measured in Cell-Based System Using Plate Reader - 2061-06_Inhibitor_Dose_CherryPick [AID463229, Type: confirmatory]
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11
[SID24784938]
Potency 2.9093qHTS for induction of synthetic lethality in tumor cells producing 2HG: qHTS for the HT-1080-IDH1KD cell line [AID686971, Type: confirmatory]
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12
[SID24784938]
Potency 3.6537qHTS of small molecules that selectively kill Giardia lamblia: Hit Validation. [AID588397, Type: confirmatory]
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13
[SID24784938]
Potency 4.4668qHTS Assay for Inhibitors of Fructose-1,6-bisphosphate Aldolase from Giardia Lamblia: Mammalian cellular toxicity [AID2786, Type: confirmatory]
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14
[SID24784938]
Potency 4.6109qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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15
[SID24784938]
Potency 5.0119qHTS for inhibitors of ROR gamma transcriptional activity [AID2551, Type: confirmatory]nuclear receptor ROR-gamma isoform 1 [Mus musculus] [gi:188536040]
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16
[SID24784938]
AC50_uM 6.117HsHsp90 Counterscreen Measured in Microorganism System Using Plate Reader - 2121-02_Inhibitor_Dose_CherryPick_Activity [AID540270, Type: confirmatory]heat shock protein HSP 90-alpha isoform 2 [Homo sapiens] [gi:154146191]
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17
[SID24784938]
Potency 6.3096qHTS Assay for Inhibitors of Human Muscle isoform 2 Pyruvate Kinase [AID1634, Type: confirmatory]pyruvate kinase PKM isoform a [Homo sapiens] [gi:33286418]
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18
[SID24784938]
Potency 6.5064Secondary assay for Inhibitors of Human Pyruvate Kinase M2 isoform: FLuc Counterscreen [AID2265, Type: confirmatory]luciferase [Photuris pennsylvanica] [gi:1669525]
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19
[SID24784938]
Potency 6.5064Secondary Assay for Luciferase (Kinase-Glo TM) Inhibition Counterscreen [AID2530, Type: confirmatory]luciferase [Photuris pennsylvanica] [gi:1669525]
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20
[SID24784938]
Potency 7.3003Confirmation Assay for Inhibitors of Leishmania Mexicana Pyruvate Kinase (LmPK) [AID2559, Type: confirmatory]pyruvate kinase [Leishmania mexicana mexicana] [gi:290753097]
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