SMR000009277 (CID 647508) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(11)
 
 
Inactive(738)
 
 
Inconclusive(11)
 
 
Unspecified(2)
 
 
Top Targets:
7TM GPCR Srx(21)
 
 
alkPPc(16)
 
 
Bcl-2 like(11)
 
 
7TM GPCR Srsx(10)
 
 
Tryp SPc(10)
 
 
BioAssay Types:
Screening(495)
 
 
 
 
 
Confirmatory(239)
 
 
 
 
 
Literature(5)
 
 
BioActivity Types:
Potency(148)
 
 
 
 
IC50(59)
 
 
 
EC50(12)
 
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 762    Data Row: 762   Total Pages: 16   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID87544796]
IC50 0.935SAR analysis of compounds that inhibit NOD1 - Set 2 [AID2466, Type: confirmatory]nucleotide-binding oligomerization domain-containing protein 1 [Homo sapiens] [gi:5174617]
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2
[SID87544796]
IC50 0.935SAR analysis of compounds that inhibit NOD1 - Set 2 [AID2466, Type: confirmatory]nucleotide-binding oligomerization domain-containing protein 1 [Homo sapiens] [gi:5174617]
View
3
[SID89650206]
IC50 1.74SAR analysis of compounds that inhibit NOD1 - Set 3 [AID2798, Type: confirmatory]nucleotide-binding oligomerization domain-containing protein 1 [Homo sapiens] [gi:5174617]
View
4
[SID89650206]
IC50 1.74SAR analysis of compounds that inhibit NOD1 - Set 3 [AID2798, Type: confirmatory]nucleotide-binding oligomerization domain-containing protein 1 [Homo sapiens] [gi:5174617]
View
5
[SID87544796]
IC50 4.1SAR analysis of GM-Tri-DAP induced IL-8 secretion in MCF-7/NOD1 cells - Set 2 [AID2505, Type: confirmatory]IL8 gene product [Homo sapiens] [gi:10834978]
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6
[SID87544796]
IC50 4.1SAR analysis of GM-Tri-DAP induced IL-8 secretion in MCF-7/NOD1 cells - Set 2 [AID2505, Type: confirmatory]IL8 gene product [Homo sapiens] [gi:10834978]
View
7
[SID87544796]
IC50 4.1SAR analysis of GM-Tri-DAP induced IL-8 secretion in MCF-7/NOD1 cells - Set 2 [AID2505, Type: confirmatory]IL8 gene product [Homo sapiens] [gi:10834978]
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8
[SID845174]
 CYP2C9 Assay [AID777, Type: screening]cytochrome P450, family 2, subfamily C, polypeptide 9 [Homo sapiens] [gi:13699818]
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9
[SID845174]
 CYP2C9 Assay [AID777, Type: screening]cytochrome P450, family 2, subfamily C, polypeptide 9 [Homo sapiens] [gi:13699818]
View
10
[SID845174]
 CYP2C9 Assay [AID777, Type: screening]cytochrome P450, family 2, subfamily C, polypeptide 9 [Homo sapiens] [gi:13699818]
View
11
[SID845174]
 Allosteric Modulators of D1 Receptors: Secondary Assay 2 [AID647, Type: other]
View
12
[SID845174]
 Allosteric Modulators of D1 Receptors: Primary Screen [AID641, Type: screening]
View
13
[SID845174]
 Allosteric Modulators of D1 Receptors: Confirmation Screen [AID642, Type: other]
View
14
[SID845174]
 HTS Assay for Inhibitors of Akt Phophorylation: Primary Screen [AID651550, Type: screening]RAC-alpha serine/threonine-protein kinase [gi:60391226]
View
15
[SID845174]
 HTS Assay for Inhibitors of Akt Phophorylation: Primary Screen [AID651550, Type: screening]RAC-alpha serine/threonine-protein kinase [gi:60391226]
View
16
[SID845174]
 HTS Assay for Inhibitors of Akt Phophorylation: Primary Screen [AID651550, Type: screening]RAC-alpha serine/threonine-protein kinase [gi:60391226]
View
17
[SID845174]
EC50 uHTS luminescence assay for the identification of compounds that inhibit NOD2 [AID1566, Type: confirmatory]nucleotide-binding oligomerization domain-containing protein 2 [Homo sapiens] [gi:11545912]
View
18
[SID845174]
EC50 uHTS luminescence assay for the identification of compounds that inhibit NOD2 [AID1566, Type: confirmatory]nucleotide-binding oligomerization domain-containing protein 2 [Homo sapiens] [gi:11545912]
View
19
[SID845174]
EC50 uHTS luminescence assay for the identification of compounds that inhibit NOD2 [AID1566, Type: confirmatory]nucleotide-binding oligomerization domain-containing protein 2 [Homo sapiens] [gi:11545912]
View
20
[SID845174]
 HTS for small molecule inhibitors of CHOP to regulate the unfolded protein response to ER stress [AID2732, Type: screening]Ddit3 gene product [Mus musculus] [gi:160707929]
View
21
[SID845174]
EC50 uHTS luminescence assay for the identification of compounds that inhibit NOD1 [AID1578, Type: confirmatory]nucleotide-binding oligomerization domain-containing protein 1 [Homo sapiens] [gi:5174617]
View
22
[SID845174]
EC50 uHTS luminescence assay for the identification of compounds that inhibit NOD1 [AID1578, Type: confirmatory]nucleotide-binding oligomerization domain-containing protein 1 [Homo sapiens] [gi:5174617]
View
23
[SID845174]
 Assay for HTS of Gi/Go-linked GPCRs using mGluR8: Primary Screening [AID488969, Type: screening]metabotropic glutamate receptor 8 [Rattus norvegicus] [gi:1575471]
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24
[SID845174]
 Assay for HTS of Gi/Go-linked GPCRs using mGluR8: Primary Screening [AID488969, Type: screening]metabotropic glutamate receptor 8 [Rattus norvegicus] [gi:1575471]
View
25
[SID845174]
 Assay for HTS of Gi/Go-linked GPCRs using mGluR8: Primary Screening [AID488969, Type: screening]metabotropic glutamate receptor 8 [Rattus norvegicus] [gi:1575471]
View
26
[SID845174]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
View
27
[SID845174]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
View
28
[SID89650206]
IC50 20SAR analysis of inhibitors of TNFa specific NF-kB induction - Set 3 [AID2801, Type: confirmatory]TNF gene product [Homo sapiens] [gi:25952111]
View
29
[SID89650206]
IC50 20SAR analysis of inhibitors of TNFa specific NF-kB induction - Set 3 [AID2801, Type: confirmatory]TNF gene product [Homo sapiens] [gi:25952111]
View
30
[SID87544796]
IC50 20SAR analysis of inhibitors of TNFa specific NF-kB induction - Set 2 [AID2483, Type: confirmatory]TNF gene product [Homo sapiens] [gi:25952111]
View
31
[SID87544796]
IC50 20SAR analysis of inhibitors of TNFa specific NF-kB induction - Set 2 [AID2483, Type: confirmatory]TNF gene product [Homo sapiens] [gi:25952111]
View
32
[SID89650206]
IC50 20SAR analysis of compounds that inhibit NOD2 - Set 3 [AID2799, Type: confirmatory]nucleotide-binding oligomerization domain-containing protein 2 [Homo sapiens] [gi:11545912]
View
33
[SID89650206]
IC50 20SAR analysis of compounds that inhibit NOD2 - Set 3 [AID2799, Type: confirmatory]nucleotide-binding oligomerization domain-containing protein 2 [Homo sapiens] [gi:11545912]
View
34
[SID89650206]
IC50 20SAR analysis of compounds that inhibit NOD2 - Set 3 [AID2799, Type: confirmatory]nucleotide-binding oligomerization domain-containing protein 2 [Homo sapiens] [gi:11545912]
View
35
[SID87544796]
IC50 20SAR analysis of compounds that inhibit NOD2 - Set 2 [AID2475, Type: confirmatory]nucleotide-binding oligomerization domain-containing protein 2 [Homo sapiens] [gi:11545912]
View
36
[SID87544796]
IC50 20SAR analysis of compounds that inhibit NOD2 - Set 2 [AID2475, Type: confirmatory]nucleotide-binding oligomerization domain-containing protein 2 [Homo sapiens] [gi:11545912]
View
37
[SID87544796]
IC50 20SAR analysis of compounds that inhibit NOD2 - Set 2 [AID2475, Type: confirmatory]nucleotide-binding oligomerization domain-containing protein 2 [Homo sapiens] [gi:11545912]
View
38
[SID87544796]
IC50 20SAR analysis of compounds that are cytotoxic to HEK293 - Set 2 [AID2469, Type: confirmatory]
View
39
[SID89650206]
IC50 20SAR analysis of compounds that are cytotoxic to HEK293 - Set 3 [AID2800, Type: confirmatory]
View
40
[SID87544796]
IC50 25SAR analysis of NF-kappaB dependent luciferase using Doxorucibin as an inducer - Set 2 [AID2789, Type: confirmatory]nucleotide-binding oligomerization domain-containing protein 1 [Homo sapiens] [gi:5174617]
View
41
[SID87544796]
IC50 25SAR analysis of NF-kappaB dependent luciferase using Doxorucibin as an inducer - Set 2 [AID2789, Type: confirmatory]nucleotide-binding oligomerization domain-containing protein 1 [Homo sapiens] [gi:5174617]
View
42
[SID87544796]
IC50 25SAR analysis of NF-kappaB dependent luciferase using PMA/Ionomycin as an inducer - 2 [AID2792, Type: confirmatory]nucleotide-binding oligomerization domain-containing protein 1 [Homo sapiens] [gi:5174617]
View
43
[SID87544796]
IC50 25SAR analysis of NF-kappaB dependent luciferase using PMA/Ionomycin as an inducer - 2 [AID2792, Type: confirmatory]nucleotide-binding oligomerization domain-containing protein 1 [Homo sapiens] [gi:5174617]
View
44
[SID87544796]
IC50 25SAR analysis of NF-kappaB dependent luciferase using DAP as an inducer - Set 2 [AID2793, Type: confirmatory]nucleotide-binding oligomerization domain-containing protein 1 [Homo sapiens] [gi:5174617]
View
45
[SID87544796]
IC50 25SAR analysis of NF-kappaB dependent luciferase using DAP as an inducer - Set 2 [AID2793, Type: confirmatory]nucleotide-binding oligomerization domain-containing protein 1 [Homo sapiens] [gi:5174617]
View
46
[SID87544796]
IC50 25SAR analysis of Muramyl dipeptide (MDP) induced IL-8 secretion in MCF-7/NOD2 cells - Set 2 [AID2503, Type: confirmatory]IL8 gene product [Homo sapiens] [gi:10834978]
View
47
[SID87544796]
IC50 25SAR analysis of Muramyl dipeptide (MDP) induced IL-8 secretion in MCF-7/NOD2 cells - Set 2 [AID2503, Type: confirmatory]IL8 gene product [Homo sapiens] [gi:10834978]
View
48
[SID87544796]
IC50 25SAR analysis of Muramyl dipeptide (MDP) induced IL-8 secretion in MCF-7/NOD2 cells - Set 2 [AID2503, Type: confirmatory]IL8 gene product [Homo sapiens] [gi:10834978]
View
49
[SID87544796]
IC50 25SAR analysis of Tumor necrosis factor alpha (TNF-alpha) induced IL-8 secretion in MCF-7/NOD1 cells - Set 2 [AID2504, Type: confirmatory]IL8 gene product [Homo sapiens] [gi:10834978]
View
50
[SID87544796]
IC50 25SAR analysis of Tumor necrosis factor alpha (TNF-alpha) induced IL-8 secretion in MCF-7/NOD1 cells - Set 2 [AID2504, Type: confirmatory]IL8 gene product [Homo sapiens] [gi:10834978]
View