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SMR000009277 (CID 647508) - Compound BioActivity Data
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BioActivity Outcomes:
Active(11)
 
 
Inactive(837)
 
 
Inconclusive(12)
 
 
Unspecified(2)
 
 
Top Targets:
7tm 4(48)
 
 
alkPPc(16)
 
 
Bcl-2 like(12)
 
 
Tryp SPc(11)
 
 
NACHT(10)
 
 
 
BioAssay Types:
Screening(561)
 
 
 
 
 
Confirmatory(266)
 
 
 
 
 
Literature(11)
 
 
BioActivity Types:
Potency(169)
 
 
 
 
IC50(64)
 
 
 
EC50(12)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 791    Data Row: 862   Total Pages: 44   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID87544796]
IC50_Mean 0.935SAR analysis of compounds that inhibit NOD1 - Set 2 [AID2466, Type: confirmatory]nucleotide-binding oligomerization domain-containing protein 1 [Homo sapiens] [gi:5174617]
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2
[SID89650206]
IC50_Mean 1.74SAR analysis of compounds that inhibit NOD1 - Set 3 [AID2798, Type: confirmatory]nucleotide-binding oligomerization domain-containing protein 1 [Homo sapiens] [gi:5174617]
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3
[SID87544796]
IC50 4.1SAR analysis of GM-Tri-DAP induced IL-8 secretion in MCF-7/NOD1 cells - Set 2 [AID2505, Type: confirmatory]interleukin-8 precursor [Homo sapiens] [gi:10834978]
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4
[SID845174]
CYP2C9 Assay [AID777, Type: screening]cytochrome P450 2C9 precursor [Homo sapiens] [gi:13699818]
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5
[SID845174]
EC50 uHTS luminescence assay for the identification of compounds that inhibit NOD1 [AID1578, Type: confirmatory]nucleotide-binding oligomerization domain-containing protein 1 [Homo sapiens] [gi:5174617]
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6
[SID845174]
HTS for small molecule inhibitors of CHOP to regulate the unfolded protein response to ER stress [AID2732, Type: screening]DNA damage-inducible transcript 3 protein [Mus musculus] [gi:160707929]
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7
[SID845174]
Allosteric Modulators of D1 Receptors: Primary Screen [AID641, Type: screening]
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8
[SID845174]
Allosteric Modulators of D1 Receptors: Confirmation Screen [AID642, Type: other]
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9
[SID845174]
Allosteric Modulators of D1 Receptors: Secondary Assay 2 [AID647, Type: other]
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10
[SID845174]
EC50 uHTS luminescence assay for the identification of compounds that inhibit NOD2 [AID1566, Type: confirmatory]nucleotide-binding oligomerization domain-containing protein 2 isoform 1 [Homo sapiens] [gi:11545912]
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11
[SID845174]
HTS Assay for Inhibitors of Akt Phophorylation: Primary Screen [AID651550, Type: screening]RAC-alpha serine/threonine-protein kinase [gi:60391226]
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12
[SID845174]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
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13
[SID845174]
Assay for HTS of Gi/Go-linked GPCRs using mGluR8: Primary Screening [AID488969, Type: screening]metabotropic glutamate receptor 8 [Rattus norvegicus] [gi:1575471]
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14
[SID87544796]
IC50_Mean 20SAR analysis of compounds that are cytotoxic to HEK293 - Set 2 [AID2469, Type: confirmatory]
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15
[SID89650206]
IC50_Mean 20SAR analysis of compounds that are cytotoxic to HEK293 - Set 3 [AID2800, Type: confirmatory]
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16
[SID89650206]
IC50_Mean 20SAR analysis of compounds that inhibit NOD2 - Set 3 [AID2799, Type: confirmatory]nucleotide-binding oligomerization domain-containing protein 2 isoform 1 [Homo sapiens] [gi:11545912]
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17
[SID87544796]
IC50_Mean 20SAR analysis of compounds that inhibit NOD2 - Set 2 [AID2475, Type: confirmatory]nucleotide-binding oligomerization domain-containing protein 2 isoform 1 [Homo sapiens] [gi:11545912]
View
18
[SID87544796]
IC50_Mean 20SAR analysis of inhibitors of TNFa specific NF-kB induction - Set 2 [AID2483, Type: confirmatory]tumor necrosis factor [Homo sapiens] [gi:25952111]
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19
[SID89650206]
IC50_Mean 20SAR analysis of inhibitors of TNFa specific NF-kB induction - Set 3 [AID2801, Type: confirmatory]tumor necrosis factor [Homo sapiens] [gi:25952111]
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20
[SID87544796]
IC50 25SAR analysis of Muramyl dipeptide (MDP) induced IL-8 secretion in MCF-7/NOD2 cells - Set 2 [AID2503, Type: confirmatory]interleukin-8 precursor [Homo sapiens] [gi:10834978]
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