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2-chloro-5-nitrobenzanilide (CID 644213) - Compound BioActivity Data
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BioActivity Outcomes:
Active(46)
 
 
Inactive(980)
 
 
Inconclusive(97)
 
 
Unspecified(20)
 
 
Top Targets:
7tm 4(45)
 
 
 
NR LBD TR(17)
 
 
 
 
p450(14)
 
 
 
 
NR LBD PPAR(14)
 
 
 
 
ANK(13)
 
 
 
BioAssay Types:
Confirmatory(612)
 
 
 
 
 
Screening(426)
 
 
 
 
Literature(45)
 
 
 
 
Summary(25)
 
 
 
 
BioActivity Types:
Potency(533)
 
 
 
 
 
IC50(44)
 
 
 
EC50(6)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 873    Data Row: 1143   Total Pages: 58   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID11114114]
Potency 0.7943qHTS Assay for Inhibitors and Substrates of Cytochrome P450 2C19 [AID899, Type: confirmatory]cytochrome P450 2C19 precursor [Homo sapiens] [gi:4503219]
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2
[SID124880756]
Potency 1.2197qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway [AID651741, Type: confirmatory]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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3
[SID26732595]
Potency 1.4581qHTS of Nrf2 Activators: Hit Validation in Primary Assay [AID651593, Type: confirmatory]Nrf2 [Homo sapiens] [gi:693842]
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4
[SID11114114]
Potency 1.5849qHTS Assay for Identification of Small Molecule Agonists for Thrombopoietin (TPO) Signaling Pathway [AID917, Type: confirmatory]Thrombopoietin [Homo sapiens] [gi:120660324]
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5
[SID124880756]
Potency-Replicate_1 3.0638qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway measured by Nrf2-dependant transcriptional activity [AID720636, Type: confirmatory]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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6
[SID103518515]
IC50 3.3Antagonist activity at human PPARgamma receptor expressed in Saccharomyces cerevisiae AH109 co-transfected with mouse CBP assessed as inhibition of rosiglitazone-induced LBD-CBP interaction by alpha-galactosidase based yeast two hybrid assay [AID396057, Type: Literature]Peroxisome proliferator-activated receptor gamma [gi:13432234]
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7
[SID11114114]
Potency 6.3096qHTS Assay for Inhibitors and Substrates of Cytochrome P450 2C9 [AID883, Type: confirmatory]cytochrome P450 2C9 precursor [Homo sapiens] [gi:13699818]
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8
[SID144212310]
Potency-Replicate_1 7.6959qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway [AID743202, Type: confirmatory]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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9
[SID103518515]
IC50 7.94328Antiplasmodial activity against Plasmodium falciparum 7G8 after 72 hrs by SYBR green assay [AID524791, Type: Literature]
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10
[SID50104878]
Potency 8.9125qHTS for differential inhibitors of proliferation of Plasmodium falciparum line 7G8 [AID1815, Type: confirmatory]
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11
[SID50104878]
Potency 10qHTS for differential inhibitors of proliferation of Plasmodium falciparum line HB3 [AID1886, Type: confirmatory]
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12
[SID103518515]
IC50 10Antiplasmodial activity against Plasmodium falciparum D10 after 72 hrs by SYBR green assay [AID524792, Type: Literature]
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13
[SID103518515]
IC50 10Antiplasmodial activity against Plasmodium falciparum 3D7 after 72 hrs by SYBR green assay [AID524790, Type: Literature]
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14
[SID103518515]
IC50 10Antiplasmodial activity against Plasmodium falciparum HB3 after 72 hrs by SYBR green assay [AID524795, Type: Literature]
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15
[SID103518515]
IC50 10Antiplasmodial activity against Plasmodium falciparum W2 after 72 hrs by SYBR green assay [AID524796, Type: Literature]
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16
[SID50104878]
Potency 11.2202qHTS for differential inhibitors of proliferation of Plasmodium falciparum line GB4 [AID1816, Type: confirmatory]
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17
[SID50104878]
Potency 11.2202qHTS for differential inhibitors of proliferation of Plasmodium falciparum line 3D7 [AID1876, Type: confirmatory]
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18
[SID50104878]
Potency 11.2202qHTS for differential inhibitors of proliferation of Plasmodium falciparum line D10 [AID1877, Type: confirmatory]
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19
[SID103518515]
IC50 12.5892Antiplasmodial activity against Plasmodium falciparum GB4 after 72 hrs by SYBR green assay [AID524794, Type: Literature]
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20
[SID50104878]
Potency 12.5893qHTS for differential inhibitors of proliferation of Plasmodium falciparum line W2 [AID1883, Type: confirmatory]
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