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2-chloro-5-nitrobenzanilide (CID 644213) - Compound BioActivity Data
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BioActivity Outcomes:
Active(46)
 
 
Inactive(966)
 
 
Inconclusive(102)
 
 
Unspecified(19)
 
 
Top Targets:
7TM GPCR Srx(28)
 
 
 
NR LBD TR(17)
 
 
 
 
7TM GPCR Srsx(16)
 
 
NR LBD PPAR(14)
 
 
 
 
p450(14)
 
 
 
 
BioAssay Types:
Confirmatory(611)
 
 
 
 
 
Screening(423)
 
 
 
 
Literature(39)
 
 
 
 
Summary(25)
 
 
 
 
BioActivity Types:
Potency(531)
 
 
 
 
 
IC50(44)
 
 
 
EC50(6)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 870    Data Row: 1133   Total Pages: 23   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID11114114]
Potency 0.7943qHTS Assay for Inhibitors and Substrates of Cytochrome P450 2C19 [AID899, Type: confirmatory]cytochrome P450 2C19 precursor [Homo sapiens] [gi:4503219]
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2
[SID124880756]
Potency 1.2197qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway [AID651741, Type: confirmatory]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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3
[SID26732595]
Potency 1.4581qHTS of Nrf2 Activators: Hit Validation in Primary Assay [AID651593, Type: confirmatory]Nrf2 [Homo sapiens] [gi:693842]
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4
[SID11114114]
Potency 1.5849qHTS Assay for Identification of Small Molecule Agonists for Thrombopoietin (TPO) Signaling Pathway [AID917, Type: confirmatory]Thrombopoietin [Homo sapiens] [gi:120660324]
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5
[SID124880756]
Potency-Replicate_1 3.0638qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway measured by Nrf2-dependant transcriptional activity [AID720636, Type: confirmatory]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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6
[SID103518515]
IC50 3.3Antagonist activity at human PPARgamma receptor expressed in Saccharomyces cerevisiae AH109 co-transfected with mouse CBP assessed as inhibition of rosiglitazone-induced LBD-CBP interaction by alpha-galactosidase based yeast two hybrid assay [AID396057, Type: Literature]Peroxisome proliferator-activated receptor gamma [gi:13432234]
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7
[SID11114114]
Potency 6.3096qHTS Assay for Inhibitors and Substrates of Cytochrome P450 2C9 [AID883, Type: confirmatory]cytochrome P450 2C9 precursor [Homo sapiens] [gi:13699818]
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8
[SID103518515]
IC50 7.94328Antiplasmodial activity against Plasmodium falciparum 7G8 after 72 hrs by SYBR green assay [AID524791, Type: Literature]
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9
[SID50104878]
Potency 8.9125qHTS for differential inhibitors of proliferation of Plasmodium falciparum line 7G8 [AID1815, Type: confirmatory]
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10
[SID103518515]
IC50 10Antiplasmodial activity against Plasmodium falciparum 3D7 after 72 hrs by SYBR green assay [AID524790, Type: Literature]
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11
[SID103518515]
IC50 10Antiplasmodial activity against Plasmodium falciparum D10 after 72 hrs by SYBR green assay [AID524792, Type: Literature]
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12
[SID103518515]
IC50 10Antiplasmodial activity against Plasmodium falciparum HB3 after 72 hrs by SYBR green assay [AID524795, Type: Literature]
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13
[SID103518515]
IC50 10Antiplasmodial activity against Plasmodium falciparum W2 after 72 hrs by SYBR green assay [AID524796, Type: Literature]
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14
[SID50104878]
Potency 10qHTS for differential inhibitors of proliferation of Plasmodium falciparum line HB3 [AID1886, Type: confirmatory]
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15
[SID50104878]
Potency 11.2202qHTS for differential inhibitors of proliferation of Plasmodium falciparum line 3D7 [AID1876, Type: confirmatory]
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16
[SID50104878]
Potency 11.2202qHTS for differential inhibitors of proliferation of Plasmodium falciparum line D10 [AID1877, Type: confirmatory]
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17
[SID50104878]
Potency 11.2202qHTS for differential inhibitors of proliferation of Plasmodium falciparum line GB4 [AID1816, Type: confirmatory]
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18
[SID103518515]
IC50 12.5892Antiplasmodial activity against Plasmodium falciparum GB4 after 72 hrs by SYBR green assay [AID524794, Type: Literature]
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19
[SID50104878]
Potency 12.5893qHTS for differential inhibitors of proliferation of Plasmodium falciparum line W2 [AID1883, Type: confirmatory]
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20
[SID26752211]
Potency 14.1254qHTS assay for environmental chemicals that activate the Aryl hydrocarbon Receptor (AhR) signaling pathway [AID651777, Type: confirmatory]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
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21
[SID144212310]
Ratio Potency (uM) 14.7772qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway: Summary [AID743219, Type: summary]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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22
[SID144212310]
AhR Potency (uM) 19.3312qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway: Summary [AID743122, Type: summary]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
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23
[SID144212310]
Ratio Potency (uM) 21.0489qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway: Summary [AID743063, Type: summary]AR protein [Homo sapiens] [gi:124375976]
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24
[SID144212310]
Potency-Replicate_1 24.5412qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway [AID743035, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
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25
[SID124880755]
Potency 28.1838qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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26
[SID124880752]
Potency 29.8554qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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27
[SID144212310]
Potency-Replicate_1 54.4827qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway [AID743085, Type: confirmatory]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
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28
[SID144212310]
Potency-Replicate_1 54.941qHTS assay to identify small molecule antagonists of the vitamin D receptor (VDR) signaling pathway [AID743223, Type: confirmatory]vitamin D (1,25- dihydroxyvitamin D3) receptor [Homo sapiens] [gi:216409708]
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29
[SID144212310]
Potency-Replicate_1 61.1306qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway [AID743065, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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30
[SID144212310]
Potency-Replicate_1 68.5896qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
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31
[SID144212310]
Potency-Replicate_1 68.5896qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
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32
[SID144212310]
Potency-Replicate_1 68.5896qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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33
[SID26732595]
Luminescence-based cell-based high throughput confirmation assay for activators of the Aryl Hydrocarbon Receptor (AHR) [AID2845, Type: screening]aryl hydrocarbon receptor precursor [Homo sapiens] [gi:4502003]
View
34
[SID26732595]
Luminescence-based primary cell-based high throughput screening assay to identify activators of the Aryl Hydrocarbon Receptor (AHR) [AID2796, Type: screening]aryl hydrocarbon receptor precursor [Homo sapiens] [gi:4502003]
View
35
[SID11114114]
Cytochrome panel assay with activity outcomes [AID1851_1, Type: other]cytochrome P450 2C19 precursor [Homo sapiens] [gi:4503219]
View
36
[SID26732595]
Counterscreen for activators of the Aryl Hydrocarbon Receptor (AHR): luminescence-based cell-based high throughput screening assay to identify activators of the Pregnane X Receptor (PXR) [AID434939, Type: screening]nuclear receptor subfamily 1 group I member 2 isoform 1 [Homo sapiens] [gi:34398348]
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37
[SID11114114]
Cytochrome panel assay with activity outcomes [AID1851_5, Type: other]cytochrome P450 2C9 precursor [Homo sapiens] [gi:13699818]
View
38
[SID85787762]
Luminescence Cell-Based Primary HTS to Identify Inhibitors of STK33 [AID2330, Type: screening]serine/threonine kinase 33 [Homo sapiens] [gi:12830367]
View
39
[SID144212310]
qHTS assay to identify small molecule antagonists of the glucocorticoid receptor (GR) signaling pathway: Summary [AID720725, Type: summary]glucocorticoid receptor [Homo sapiens] [gi:311348376]
View
40
[SID144212310]
qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway: Summary [AID743226, Type: summary]peroxisome proliferator-activated receptor delta [Homo sapiens] [gi:216409690]
View
41
[SID144212310]
qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor gamma (PPARg) signaling pathway: Summary [AID743199, Type: summary]peroxisome proliferator activated receptor gamma [Homo sapiens] [gi:216409692]
View
42
[SID26732595]
uHTS of small molecular inhibitors for p47phox, a regulatory protein of NADPH oxidases (Noxs) [AID1274, Type: screening]neutrophil cytosol factor 1 [Homo sapiens] [gi:115298672]
View
43
[SID26732595]
Luminescence-based cell-based primary high throughput screening assay to identify activators of the DAF-12 from the parasite H. contortus (hcDAF-12) [AID652067, Type: screening]Protein DAF-12, isoform a [Caenorhabditis elegans] [gi:71987181]
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44
[SID11114114]
Cytochrome panel assay with activity outcomes [AID1851_4, Type: other]cytochrome P450 1A2 [Homo sapiens] [gi:73915100]
View
45
[SID11114114]
p450-cyp1a2 [AID410, Type: confirmatory]cytochrome P450 1A2 [Homo sapiens] [gi:73915100]
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46
[SID11111477]
p450-cyp1a2 [AID410, Type: confirmatory]cytochrome P450 1A2 [Homo sapiens] [gi:73915100]
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47
[SID26732595]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
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48
[SID26752211]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838, Type: other]
View
49
[SID103518515]
Antibacterial activity against Staphylococcus aureus MTCC 290 after 24 hrs [AID288206, Type: Literature]
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50
[SID103518515]
Antibacterial activity against Bacillus subtilis MTCC 2063 after 24 hrs [AID288207, Type: Literature]
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