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Cannabidiol (CID 644019) - Compound BioActivity Data
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BioActivity Outcomes:
Active(8)
 
 
Inconclusive(1)
 
 
Unspecified(28)
 
 
Top Targets:
7TM GPCR Srsx(2)
 
 
 
Amidase(1)
 
 
ANK(1)
 
 
p450(1)
 
 
BioAssay Types:
Literature(37)
 
 
 
 
BioActivity Types:
Ki(3)
 
 
 
EC50(2)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 37    Data Row: 37   Total Pages: 2   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103460177]
EC50 0.096Agonist activity at rat TRPA1 channel expressed in HEK293 cells assessed as increase in intracellular calcium influx [AID482146, Type: Literature]Transient receptor potential cation channel subfamily A member 1 [gi:56749669]
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2
[SID103460177]
EC50 0.445Binding affinity to GPR55 [AID482752, Type: Literature]
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3
[SID103460177]
Ki 2.4Displacement of [3H]CP-55940 from human cannabinoid CB1 receptor expressed in CHO cells [AID482748, Type: Literature]Cannabinoid receptor 1 [gi:115562]
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4
[SID103460177]
Ki 10Displacement of [3H]CP-55940 from human cannabinoid CB2 receptor expressed in CHO cells [AID482749, Type: Literature]Cannabinoid receptor 2 [gi:461697]
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5
[SID103460177]
Ability to suppress the production of reactive oxygen intermediates by activated RAW 264.7 macrophages from BALB/c mice at 8 ug/ml [AID260281, Type: Literature]
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6
[SID103460177]
Ability to suppress nitric acid production by LPS-activated peritoneal macrophages form C57BL/6 mice at 4 ug/ml [AID260282, Type: Literature]
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7
[SID103460177]
Ability to suppress nitric acid production by LPS-activated peritoneal macrophages form C57BL/6 mice at 8 ug/ml [AID260283, Type: Literature]
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8
[SID103460177]
Ability to suppress TNFalpha production by LPS-activated peritoneal macrophages form C57BL/6 mice at 8 ug/ml [AID260286, Type: Literature]
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9
[SID103460177]
Ki 10Displacement of [3H]HU243 from CB1 receptor in Sabra rat brain [AID260287, Type: Literature]Cannabinoid receptor 1 [gi:115563]
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10
[SID103460177]
Antibacterial activity against methicillin-resistant Staphylococcus aureus SA1199B after 18 hrs [AID362541, Type: Literature]
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11
[SID103460177]
Antibacterial activity against macrolide-resistant Staphylococcus aureus RN4220 after 18 hrs [AID362542, Type: Literature]
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12
[SID103460177]
Antibacterial activity against tetracycline-resistant Staphylococcus aureus XU212 after 18 hrs [AID362543, Type: Literature]
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13
[SID103460177]
Antibacterial activity against methicillin-resistant Staphylococcus aureus ATCC 25923 after 18 hrs [AID362544, Type: Literature]
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14
[SID103460177]
Antibacterial activity against epidemic methicillin-resistant Staphylococcus aureus 15 after 18 hrs [AID362545, Type: Literature]
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15
[SID103460177]
Antibacterial activity against epidemic methicillin-resistant Staphylococcus aureus 16 after 18 hrs [AID362546, Type: Literature]
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16
[SID103460177]
Induction of bone formation in GPR55 knockout male mouse assessed as increase in tibia mass volume [AID482746, Type: Literature]
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17
[SID103460177]
Induction of bone formation in GPR55 knockout male mouse assessed as increase in femur mass volume [AID482747, Type: Literature]
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18
[SID103460177]
Spontaneous activity in mice at a dose 40 mg/kg [AID130147, Type: Literature]
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19
[SID103460177]
Compound was evaluated for the percent antagonism in tail-flick test in mice at dose 40 mg/kg [AID130160, Type: Literature]
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20
[SID103460177]
The difference between the preinjection and postinjection (60 min) temperatures in mice was evaluated at a dose 100 mg/kg [AID132300, Type: Literature]
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