Bookmark and Share

BioActivity Data for Compound Cannabidiol (CID 644019)

BioActivity Outcomes:
Active(14)
 
 
Inconclusive(1)
 
 
Unspecified(29)
 
 
Top Targets:
7tm 4(4)
 
 
 
ANK(1)
 
 
Amidase(1)
 
 
p450(1)
 
 
BioAssay Types:
Literature(44)
 
 
 
 
BioAssay Categories:
In vitro(1)
 
 
Biochemical(11)
 
 
 
ADME(4)
 
 
Cell-based(8)
 
 
 
BioActivity Types:
Ki(7)
 
 
 
EC50(2)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 44    Data Row: 44   Total Pages: 3   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103460177]
EC50 0.096Agonist activity at rat TRPA1 channel expressed in HEK293 cells assessed as increase in intracellular calcium influx [AID482146, Type: Literature]Transient receptor potential cation channel subfamily A member 1 [gi:56749669]
View
2
[SID103460177]
Ki 0.23Binding affinity for Cannabinoid receptor 2 by the ability to displace radiolabeled CP-55940 from mouse spleen synaptosomes [AID49852, Type: Literature]Cannabinoid receptor 2 [gi:1345700]
View
3
[SID103460177]
EC50 0.445Binding affinity to GPR55 [AID482752, Type: Literature]
View
4
[SID103460177]
Ki 1.265Binding affinity for Cannabinoid receptor 1 by the ability to displace radiolabeled CP-55940 from purified rat forebrain synaptosomes [AID49491, Type: Literature]Cannabinoid receptor 1 [gi:115563]
View
5
[SID103460177]
Ki 2.4Displacement of [3H]CP-55940 from human cannabinoid CB1 receptor expressed in CHO cells [AID482748, Type: Literature]Cannabinoid receptor 1 [gi:115562]
View
6
[SID103460177]
Ki 2.86Binding affinity to human CB2 receptor [AID1127483, Type: Literature]Cannabinoid receptor 2 [gi:461697]
View
7
[SID103460177]
Ki 4.35Binding affinity to human CB1 receptor [AID1127482, Type: Literature]Cannabinoid receptor 1 [gi:115562]
View
8
[SID103460177]
Ki 10Displacement of [3H]CP-55940 from human cannabinoid CB2 receptor expressed in CHO cells [AID482749, Type: Literature]Cannabinoid receptor 2 [gi:461697]
View
9
[SID103460177]
Binding affinity towards cloned human cannabinoid receptor 2 [AID49851, Type: Literature]
View
10
[SID103460177]
Ability to suppress TNFalpha production by LPS-activated peritoneal macrophages form C57BL/6 mice at 8 ug/ml [AID260286, Type: Literature]
View
11
[SID103460177]
Ability to suppress nitric acid production by LPS-activated peritoneal macrophages form C57BL/6 mice at 8 ug/ml [AID260283, Type: Literature]
View
12
[SID103460177]
Ability to suppress nitric acid production by LPS-activated peritoneal macrophages form C57BL/6 mice at 4 ug/ml [AID260282, Type: Literature]
View
13
[SID103460177]
Ability to suppress the production of reactive oxygen intermediates by activated RAW 264.7 macrophages from BALB/c mice at 8 ug/ml [AID260281, Type: Literature]
View
14
[SID103460177]
Binding affinity towards cloned human Cannabinoid receptor 1 [AID49325, Type: Literature]
View
15
[SID103460177]
Ki 10Displacement of [3H]HU243 from CB1 receptor in Sabra rat brain [AID260287, Type: Literature]Cannabinoid receptor 1 [gi:115563]
View
16
[SID103460177]
Mechanism based inhibition of mouse cytochrome P450 CYP3A11 [AID624672, Type: Literature]Cytochrome P450 3A11 [gi:5921911]
View
17
[SID103460177]
Inhibitory potency against fatty acid amide hydrolase activity in mouse brain microsomes in presence of 58 uM anandamide at 160 uM [AID243998, Type: Literature]Fatty-acid amide hydrolase 1 [gi:6225311]
View
18
[SID103460177]
Selectivity ratio of Ki for human CB1 receptor to Ki for human CB2 receptor [AID1127484, Type: Literature]
View
19
[SID103460177]
Compound was evaluated for the maximum possible effect in tail-flick test in mice at dose 40 mg/kg [AID133446, Type: Literature]
View
20
[SID103460177]
Compound was evaluated for the percent antagonism in tail-flick test in mice at dose 40 mg/kg [AID130160, Type: Literature]
View