13-cis-retinal (CID 6436079) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(164)
 
 
Inactive(55)
 
 
Inconclusive(94)
 
 
Unspecified(3)
 
 
Top Targets:
NR LBD PPAR(5)
 
 
 
NR LBD TR(4)
 
 
P53(3)
 
 
NR LBD ROR li..(3)
 
 
NR LBD VDR(2)
 
 
BioAssay Types:
Confirmatory(141)
 
 
 
 
Literature(2)
 
 
 
BioActivity Types:
Potency(105)
 
 
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 146    Data Row: 316   Total Pages: 7   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID17389450]
Potency 0.4216qHTS assay to identify small molecules that stimulate interleukin-8 (IL-8) secretion [AID651758, Type: confirmatory]interleukin 8 [Homo sapiens] [gi:186368]
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2
[SID17389450]
Potency 0.4216qHTS assay to identify small molecules that stimulate interleukin-8 (IL-8) secretion [AID651758, Type: confirmatory]interleukin 8 [Homo sapiens] [gi:186368]
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3
[SID17389450]
Potency 0.4216qHTS assay to identify small molecules that stimulate interleukin-8 (IL-8) secretion [AID651758, Type: confirmatory]interleukin 8 [Homo sapiens] [gi:186368]
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4
[SID17389450]
Potency 31.6228MultiTox-Fluor Cytotoxicity Assay - LYMP1-003 - Dead Cells [AID961, Type: confirmatory]
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5
[SID17389450]
Potency 31.6228Cell Viability - LYMP2-004 [AID966, Type: confirmatory]
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6
[SID17389450]
Potency 31.6228Cell Viability - LYMP2-024 [AID988, Type: confirmatory]
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7
[SID17389450]
Potency 37.578qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway [AID651741, Type: confirmatory]NFE2L2 gene product [Homo sapiens] [gi:20149576]
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8
[SID17389450]
Potency 37.578qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway [AID651741, Type: confirmatory]NFE2L2 gene product [Homo sapiens] [gi:20149576]
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9
[SID17389450]
Potency 37.578qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway [AID651741, Type: confirmatory]NFE2L2 gene product [Homo sapiens] [gi:20149576]
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10
[SID17389450]
Potency 37.578qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway [AID651741, Type: confirmatory]NFE2L2 gene product [Homo sapiens] [gi:20149576]
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11
[SID17389450]
Potency 39.8107Cell Viability - LYMP2-022 [AID987, Type: confirmatory]
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12
[SID17389450]
Potency 39.8107Cell Viability - LYMP2-010 [AID981, Type: confirmatory]
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13
[SID17389450]
Potency 39.8107Cell Viability - LYMP2-003 [AID965, Type: confirmatory]
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14
[SID17389450]
Potency 39.8107Cell Viability - LYMP2-015 [AID971, Type: confirmatory]
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15
[SID17389450]
Potency 39.8107qHTS assay for small molecule antagonists of estrogen receptor alpha signaling [AID588513, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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16
[SID17389450]
Potency 39.8107qHTS assay for small molecule antagonists of estrogen receptor alpha signaling [AID588513, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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17
[SID17389450]
Potency 39.8107qHTS assay for small molecule antagonists of estrogen receptor alpha signaling [AID588513, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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18
[SID17389450]
Potency 39.8107qHTS assay for small molecule antagonists of estrogen receptor alpha signaling [AID588513, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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19
[SID17389450]
Potency 50.1187Cell Viability - LYMP2-017 [AID972, Type: confirmatory]
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20
[SID17389450]
Potency 50.1187Cell Viability - LYMP2-019 [AID973, Type: confirmatory]
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21
[SID17389450]
Potency 50.1187Cell Viability - LYMP2-021 [AID974, Type: confirmatory]
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22
[SID17389450]
Potency 50.1187Cell Viability - LYMP2-023 [AID975, Type: confirmatory]
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23
[SID17389450]
Potency 50.1187Cell Viability - LYMP2-002 [AID977, Type: confirmatory]
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24
[SID17389450]
Potency 50.1187Cell Viability - LYMP2-006 [AID978, Type: confirmatory]
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25
[SID17389450]
Potency 50.1187Cell Viability - LYMP2-007 [AID979, Type: confirmatory]
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26
[SID17389450]
Potency 50.1187Cell Viability - LYMP2-008 [AID980, Type: confirmatory]
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27
[SID17389450]
Potency 50.1187Cell Viability - LYMP1-003 - Assay at 40 hr [AID964, Type: confirmatory]
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28
[SID17389450]
Potency 50.1187MultiTox-Fluor Cytotoxicity Assay - LYMP1-003 - Live Cells [AID962, Type: confirmatory]
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29
[SID17389450]
Potency 50.1187Cell Viability - LYMP2-009 [AID968, Type: confirmatory]
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30
[SID17389450]
Potency 50.1187Cell Viability - LYMP2-011 [AID969, Type: confirmatory]
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31
[SID17389450]
Potency 50.1187Cell Viability - LYMP2-013 [AID970, Type: confirmatory]
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32
[SID17389450]
Potency 50.1187Cell Viability - LYMP2-018 [AID985, Type: confirmatory]
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33
[SID17389450]
Potency 50.1187Cell Viability - LYMP1-002 - Assay at 40 hr [AID994, Type: confirmatory]
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34
[SID17389450]
Potency 63.0957Cell Viability - LYMP1-002 - Assay at 24 hr [AID993, Type: confirmatory]
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35
[SID17389450]
Potency 63.0957Cell Viability - LYMP2-014 [AID983, Type: confirmatory]
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36
[SID17389450]
Potency 63.0957Cell Viability - LYMP1-003 - Assay at 24 hr [AID963, Type: confirmatory]
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37
[SID17389450]
 Cellular Toxicity (caspase-3) HepG2 [AID654, Type: confirmatory]
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38
[SID17389450]
 Cellular Toxicity (caspase-3) Mesangial [AID660, Type: confirmatory]
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39
[SID17389450]
 Cellular Toxicity (caspase-3) H-4-II-E [AID663, Type: confirmatory]
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40
[SID17389450]
 Cellular Toxicity (caspase-3) Renal Proximal Tubule [AID667, Type: confirmatory]
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41
[SID17389450]
 Cell Viability - Hek293 [AID427, Type: confirmatory]
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42
[SID17389450]
 Cell Viability - Jurkat [AID426, Type: confirmatory]
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43
[SID17389450]
 Cell Viability - BJ [AID421, Type: confirmatory]
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44
[SID17389450]
 Cell Viability Profiling of Human Lymphoblast Cell Lines [AID588812_1, Type: other]
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45
[SID17389450]
 Cell Viability Profiling of Human Lymphoblast Cell Lines [AID588812_2, Type: other]
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46
[SID17389450]
 Cell Viability Profiling of Human Lymphoblast Cell Lines [AID588812_5, Type: other]
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47
[SID17389450]
 Cell Viability Profiling of Human Lymphoblast Cell Lines [AID588812_6, Type: other]
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48
[SID17389450]
 Cell Viability Profiling of Human Lymphoblast Cell Lines [AID588812_7, Type: other]
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49
[SID17389450]
 Cell Viability Profiling of Human Lymphoblast Cell Lines [AID588812_8, Type: other]
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50
[SID17389450]
 Cell Viability Profiling of Human Lymphoblast Cell Lines [AID588812_10, Type: other]
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