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13-cis-retinal (CID 6436079) - Compound BioActivity Data
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BioActivity Outcomes:
Active(184)
 
 
Inactive(86)
 
 
Inconclusive(139)
 
 
Unspecified(3)
 
 
Top Targets:
NR LBD PPAR(13)
 
 
 
NR LBD ER(9)
 
 
 
 
NR LBD AR(9)
 
 
 
NR LBD TR(7)
 
 
 
 
NR LBD VDR(6)
 
 
 
BioAssay Types:
Confirmatory(212)
 
 
 
 
Summary(24)
 
 
 
 
Literature(3)
 
 
 
BioActivity Types:
Potency(194)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 238    Data Row: 412   Total Pages: 21   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID17389450]
Potency 0.4216qHTS assay to identify small molecules that stimulate interleukin-8 (IL-8) secretion [AID651758, Type: confirmatory]interleukin 8 [Homo sapiens] [gi:186368]
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2
[SID17389450]
Potency-Replicate_1 7.9433qHTS assay for small molecule activators of the human pregnane X receptor (PXR) signaling pathway [AID720659, Type: confirmatory]pregnane X nuclear receptor [Homo sapiens] [gi:325495557]
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3
[SID144208274]
ER Potency (uM) 9.52742qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line: Summary [AID743091, Type: summary]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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4
[SID144208274]
Potency-Replicate_1 12.9512qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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5
[SID144208274]
Potency-Replicate_1 14.5314qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
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6
[SID144208274]
Potency-Replicate_1 14.5314qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
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7
[SID144208274]
Potency-Replicate_1 16.3045qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line [AID743080, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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8
[SID144208274]
Potency-Replicate_1 25.841qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway - cell viability counter screen [AID743064, Type: confirmatory]
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9
[SID17389450]
Potency-Replicate_1 26.6032qHTS assay for small molecule antagonists of the retinoid-related orphan receptor gamma (ROR-gamma) signaling pathway - cell viability counter screen [AID720652, Type: confirmatory]
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10
[SID144208274]
Potency-Replicate_1 28.994qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway [AID743065, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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11
[SID144208274]
Potency-Replicate_1 29.2512qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway - cell viability counter screen [AID743033, Type: confirmatory]
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12
[SID17389450]
Potency 31.6228MultiTox-Fluor Cytotoxicity Assay - LYMP1-003 - Dead Cells [AID961, Type: confirmatory]
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13
[SID17389450]
Potency 31.6228Cell Viability - LYMP2-004 [AID966, Type: confirmatory]
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14
[SID17389450]
Potency 31.6228Cell Viability - LYMP2-024 [AID988, Type: confirmatory]
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15
[SID17389450]
Potency 37.578qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway [AID651741, Type: confirmatory]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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16
[SID17389450]
Potency 39.8107qHTS assay for small molecule antagonists of estrogen receptor alpha signaling [AID588513, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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17
[SID17389450]
Potency 39.8107Cell Viability - LYMP2-010 [AID981, Type: confirmatory]
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18
[SID17389450]
Potency 39.8107Cell Viability - LYMP2-022 [AID987, Type: confirmatory]
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19
[SID17389450]
Potency 39.8107Cell Viability - LYMP2-003 [AID965, Type: confirmatory]
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20
[SID17389450]
Potency 39.8107Cell Viability - LYMP2-015 [AID971, Type: confirmatory]
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