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Sorbic Acid (CID 643460) - Compound BioActivity Data
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BioActivity Outcomes:
Active(5)
 
 
Inactive(873)
 
 
Inconclusive(31)
 
 
Unspecified(14)
 
 
Top Targets:
7tm 4(36)
 
 
NR LBD AR(23)
 
 
 
 
NR LBD PPAR(23)
 
 
 
NR LBD ER(23)
 
 
NR LBD GR(14)
 
 
 
BioAssay Types:
Confirmatory(457)
 
 
 
 
 
Screening(296)
 
 
 
Literature(89)
 
 
 
 
 
Summary(63)
 
 
 
BioActivity Types:
Potency(460)
 
 
 
 
 
IC50(9)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 646    Data Row: 923   Total Pages: 47   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103553232]
IC50 0.21Antihemorrhagic activity in ddY mouse assessed as inhibition of Protobothrops flavoviridis venom-induced hemorrhage incubated with compound for 10 mins measured after 24 hrs [AID592088, Type: Literature]
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2
[SID144204715]
Potency-Replicate_1 33.4915qHTS assay to identify small molecule agonists of the androgen receptor (AR) signaling pathway using the MDA cell line [AID743040, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
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3
[SID144210502]
Potency-Replicate_1 61.1306qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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4
[SID144210502]
Potency-Replicate_1 61.1306qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
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5
[SID56462787]
Fluorescence-based biochemical primary high throughput assay to identify inhibitors of T-cell receptor (TCR)-CD3 interaction using a TAMRA-labeled TCR probe [AID651800, Type: screening]TCRAV4S1, partial [Homo sapiens] [gi:2358024]
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6
[SID17389732]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838, Type: other]
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7
[SID103553232]
Antimicrobial activity against Bacillus subtilis after 24 hrs by twofold serial dilution method [AID309842, Type: Literature]
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8
[SID103553232]
Antimicrobial activity against Staphylococcus aureus after 24 hrs by twofold serial dilution method [AID309843, Type: Literature]
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9
[SID103553232]
Antimicrobial activity against Escherichia coli after 24 hrs by twofold serial dilution method [AID309844, Type: Literature]
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10
[SID103553232]
Antifungal activity against Candida albicans after 2 days by twofold serial dilution method [AID309845, Type: Literature]
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11
[SID103553232]
Antifungal activity against Aspergillus niger after 7 days by twofold serial dilution method [AID309846, Type: Literature]
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12
[SID103553232]
Partition coefficient, log P of the compound [AID309847, Type: Literature]
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13
[SID103553232]
Inhibition of HDAC in human Hela cells nuclear extracts assessed as residual activity at 500 uM by fluorimetric assay [AID447578, Type: Literature]
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14
[SID17389732]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749, Type: Literature]
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15
[SID56462787]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
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16
[SID103553232]
pKa (acid-base dissociation constant) as determined by Liao ref: J Chem Info Model 2009 [AID781325, Type: Literature]
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17
[SID103553232]
Antifungal activity against Zygosaccharomyces bailii assessed as growth inhibition measured after 48 hr by macrodilution assay [AID1090229, Type: Literature]
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18
[SID103553232]
Antifungal activity against Saccharomyces cerevisiae ATCC 7754 at pH 3 after 48 hr by microdilution method [AID1101856, Type: Literature]
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19
[SID103553232]
Antifungal activity against Saccharomyces cerevisiae ATCC 7754 at pH 5 after 48 hr by microdilution method [AID1101859, Type: Literature]
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20
[SID17389732]
Potency 35.4813qHTS Assay for Inhibitors of GCN5L2 [AID504327, Type: confirmatory]histone acetyltransferase KAT2A [Homo sapiens] [gi:153791535]
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