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Dithiazanine (CID 6433197) - Compound BioActivity Data
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BioActivity Outcomes:
Active(150)
 
 
Inactive(324)
 
 
Inconclusive(80)
 
 
Unspecified(5)
 
 
Top Targets:
7TM GPCR Srsx(14)
 
 
 
G-alpha(12)
 
 
 
 
 
Bcl-2 like(11)
 
 
 
 
 
7TM GPCR Srx(11)
 
 
 
alkPPc(10)
 
 
 
BioAssay Types:
Screening(315)
 
 
 
 
 
Confirmatory(208)
 
 
 
 
Summary(16)
 
 
 
 
Literature(11)
 
 
BioActivity Types:
Potency(142)
 
 
 
 
IC50(42)
 
 
 
 
EC50(28)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 516    Data Row: 559   Total Pages: 28   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144206273]
Potency-Replicate_1 0.0335qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
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2
[SID144206273]
Potency-Replicate_1 0.0674qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway - cell viability counter screen [AID743074, Type: confirmatory]
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3
[SID144206273]
Ratio Potency (uM) 0.0958048qHTS assay for small molecule disruptors of the mitochondrial membrane potential: Summary [AID720637, Type: summary]
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4
[SID144206273]
Potency-Replicate_1 0.1333qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
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5
[SID144206273]
Potency-Replicate_1 0.1679qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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6
[SID144206273]
Potency-Replicate_1 0.2371qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
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7
[SID11532995]
Potency 0.3696Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation [AID504832, Type: confirmatory]
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8
[SID144206273]
Potency-Replicate_1 0.8413qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line [AID743042, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
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9
[SID11532995]
Potency 0.9285Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation [AID504834, Type: confirmatory]
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10
[SID144206273]
Potency-Replicate_1 1.6785qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line - cell viability counter screen [AID743041, Type: confirmatory]
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11
[SID144206273]
ER Potency (uM) 1.81246qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line: Summary [AID743091, Type: summary]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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12
[SID11532995]
Potency 1.8356qHTS for Inhibitors of binding or entry into cells for Lassa Virus [AID540256, Type: confirmatory]
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13
[SID144206273]
Potency-Replicate_1 1.8834qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line [AID743080, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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14
[SID144206273]
Potency-Replicate_1 2.371qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway [AID743065, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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15
[SID11532995]
Absolute IC50 (XBP1) 2.4XBP1 DR counterscreen for CHOP [AID504313, Type: confirmatory]XBP1 [Homo sapiens] [gi:47678753]
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16
[SID144206273]
Potency-Replicate_1 2.6832qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway - cell viability counter screen [AID743033, Type: confirmatory]
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17
[SID11532995]
Potency 3.1623VP16 counterscreen qHTS for inhibitors of ROR gamma transcriptional activity [AID2546, Type: confirmatory]nuclear receptor ROR-gamma isoform 1 [Mus musculus] [gi:188536040]
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18
[SID11532995]
EC50_MICROM 3.41Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS4-Galphao. [AID1872, Type: confirmatory]regulator of G-protein signaling 4 [Homo sapiens] [gi:86301151]
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19
[SID11532995]
IC50_Mean 3.73High Throughput Imaging Assay for Beta-Catenin [AID1665, Type: confirmatory]catenin beta-1 [Homo sapiens] [gi:4503131]
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20
[SID11532995]
Potency 3.9811qHTS for Inhibitors of Tau Fibril Formation, Thioflavin T Binding [AID1460, Type: confirmatory]Microtubule-associated protein tau [Homo sapiens] [gi:92096784]
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