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BioActivity Data for Compound acetone cyanohydrin (CID 6406)

BioActivity Outcomes:
Active(2)
 
 
Inactive(181)
 
 
Inconclusive(10)
 
 
Unspecified(6)
 
 
Top Targets:
NR LBD PPAR(16)
 
 
 
NR LBD AR(14)
 
 
NR LBD ER(14)
 
 
 
NR LBD Fxr(8)
 
 
NR LBD GR(8)
 
 
BioAssay Types:
Confirmatory(136)
 
 
 
Summary(52)
 
 
Literature(2)
 
 
BioAssay Categories:
In vivo(2)
 
 
Toxicity(12)
 
 
 
ADME(5)
 
 
 
BioActivity Types:
Potency(176)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 104    Data Row: 199   Total Pages: 10   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID104248042]
LC50 0.82Insecticidal activity against Musca domestica (house fly) after 24 hr [AID1101931, Type: Literature]
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2
[SID104248042]
LC50 4.7Insecticidal activity against Rhyzopertha dominica after 24 hr [AID1101932, Type: Literature]
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3
[SID104248042]
Drug level in Musca domestica (house fly) assessed as cyanide ion level per gram of insect at L99 treated as fumigation after 24 hr by spectrophotometric method [AID1110479, Type: other]
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4
[SID104248042]
Drug level in Rhyzopertha dominica assessed as cyanide ion level per gram of insect at L99 treated as fumigation after 24 hr by spectrophotometric method [AID1110478, Type: other]
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5
[SID104248042]
Insecticidal activity against Musca domestica (house fly) after 24 hr [AID1110484, Type: other]
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6
[SID104248042]
Insecticidal activity against Rhyzopertha dominica after 24 hr [AID1110483, Type: other]
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7
[SID104248042]
Drug level in Musca domestica (house fly) at 1000 ug after 24 hr by spectrophotometric method [AID1110482, Type: other]
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8
[SID104248042]
Drug level in Musca domestica (house fly) assessed as cyanide ion level per gram of insect at L99 treated topically after 24 hr by spectrophotometric method [AID1110481, Type: other]
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9
[SID144208688]
Potency-Replicate_1 qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway - cell viability counter screen [AID743086, Type: confirmatory]
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10
[SID144208688]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor gamma (PPARg) signaling pathway - cell viability counter screen [AID743194, Type: confirmatory]
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11
[SID144208688]
Potency-Replicate_1 qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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12
[SID144208688]
Potency-Replicate_1 qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
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13
[SID144208688]
qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway: Summary [AID743226, Type: summary]peroxisome proliferator-activated receptor delta [Homo sapiens] [gi:216409690]
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14
[SID144208688]
Ratio Potency (uM) qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway: Summary [AID743227, Type: summary]peroxisome proliferator-activated receptor delta [Homo sapiens] [gi:216409690]
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15
[SID144213573]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway [AID743215, Type: confirmatory]peroxisome proliferator-activated receptor delta [Homo sapiens] [gi:216409690]
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16
[SID144213573]
Potency-Replicate_1 qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway [AID743212, Type: confirmatory]peroxisome proliferator-activated receptor delta [Homo sapiens] [gi:216409690]
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17
[SID144213573]
qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway: Summary [AID743226, Type: summary]peroxisome proliferator-activated receptor delta [Homo sapiens] [gi:216409690]
View
18
[SID144213573]
Ratio Potency (uM) qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway: Summary [AID743227, Type: summary]peroxisome proliferator-activated receptor delta [Homo sapiens] [gi:216409690]
View
19
[SID144213573]
Ratio Potency (uM) qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor gamma (PPARg) signaling pathway: Summary [AID743140, Type: summary]peroxisome proliferator activated receptor gamma [Homo sapiens] [gi:216409692]
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20
[SID144213573]
Ratio Potency (uM) qHTS assay to identify small molecule agonists of the NFkB signaling pathway: Summary [AID1159518, Type: summary]nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a [Homo sapiens] [gi:119626539]
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