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trimethylchlorosilane (CID 6397) - Compound BioActivity Data
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BioActivity Outcomes:
Active(2)
 
 
Inactive(232)
 
 
Inconclusive(12)
 
 
Unspecified(1)
 
 
Top Targets:
NR LBD PPAR(13)
 
 
 
NR LBD ER(9)
 
 
NR LBD AR(9)
 
 
 
NR LBD TR(7)
 
 
NR LBD VDR(6)
 
 
BioAssay Types:
Confirmatory(212)
 
 
 
 
Summary(24)
 
 
 
Literature(2)
 
 
BioActivity Types:
Potency(194)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 235    Data Row: 247   Total Pages: 13   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID17389110]
Potency 22.3872qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1) [AID1030, Type: confirmatory]aldehyde dehydrogenase 1 family, member A1 [Homo sapiens] [gi:30582681]
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2
[SID144207419]
Ratio Potency (uM) 26.4475qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway: Summary [AID743219, Type: summary]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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3
[SID17389110]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838, Type: other]
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4
[SID17389110]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_1, Type: other]
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5
[SID17389110]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_2, Type: other]
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6
[SID17389110]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_3, Type: other]
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7
[SID17389110]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_4, Type: other]
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8
[SID17389110]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_5, Type: other]
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9
[SID17389110]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_6, Type: other]
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10
[SID17389110]
Cell Viability - N2a [AID540, Type: confirmatory]
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11
[SID17389110]
Cell Viability - NIH 3T3 [AID541, Type: confirmatory]
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12
[SID17389110]
Cell Viability - HUV-EC-C [AID542, Type: confirmatory]
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13
[SID17389110]
Cell Viability - H-4-II-E [AID543, Type: confirmatory]
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14
[SID17389110]
Potency qHTS Assay for Inhibitors and Activators of N370S glucocerebrosidase as a Potential Chaperone Treatment of Gaucher Disease [AID2101, Type: confirmatory]glucocerebrosidase [Homo sapiens] [gi:496369]
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15
[SID17389110]
Potency qHTS Assay for Inhibitors and Activators of Human alpha-Galactosidase From Spleen Homogenate [AID2107, Type: confirmatory]alpha-galactosidase [Homo sapiens] [gi:757912]
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16
[SID17389110]
Potency qHTS Assay for Allosteric/Competitive Inhibitors of Caspase-7 [AID889, Type: confirmatory]Caspase-7 [gi:1730092]
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17
[SID17389110]
Potency qHTS Assay for Inhibitors of 15-hLO (15-human lipoxygenase) [AID887, Type: confirmatory]15-lipoxygenase [Homo sapiens] [gi:1832253]
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18
[SID17389110]
Cell Viability - Renal Proximal Tubule [AID545, Type: confirmatory]
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19
[SID17389110]
Cell Viability - Mesenchymal [AID546, Type: confirmatory]
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20
[SID17389110]
Cell Viability - BJ [AID421, Type: confirmatory]
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