Bookmark and Share
Retinaldehyde (CID 638015) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(225)
 
 
Inactive(96)
 
 
Inconclusive(114)
 
 
Unspecified(16)
 
 
Top Targets:
NR LBD PPAR(13)
 
 
 
 
NR LBD ER(9)
 
 
 
NR LBD AR(9)
 
 
 
 
NR LBD TR(7)
 
 
 
 
Aldo ket red(6)
 
 
BioAssay Types:
Confirmatory(213)
 
 
 
 
Summary(24)
 
 
 
 
Literature(21)
 
 
 
 
BioActivity Types:
Potency(194)
 
 
 
 
Kd(2)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 275    Data Row: 451   Total Pages: 23   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID53812631]
Kd 0.12Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain A, Crystal Structure Of The R132k:y134f Mutant Of Cellular Retinoic Acid Binding Protein Type Ii In Complex With All- Trans-Retinal At 1.69 Angstroms Resolution [gi:146386484]
View
2
[SID53812631]
Kd 0.12Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain A, Crystal Structure Of The R132k:y134f Mutant Of Cellular Retinoic Acid Binding Protein Type Ii In Complex With All- Trans-Retinal At 1.69 Angstroms Resolution [gi:146386484]
View
3
[SID17388687]
Potency 0.4216qHTS assay to identify small molecules that stimulate interleukin-8 (IL-8) secretion [AID651758, Type: confirmatory]interleukin 8 [Homo sapiens] [gi:186368]
View
4
[SID17388687]
Potency-Replicate_1 7.0795qHTS assay for small molecule activators of the human pregnane X receptor (PXR) signaling pathway [AID720659, Type: confirmatory]pregnane X nuclear receptor [Homo sapiens] [gi:325495557]
View
5
[SID144208203]
Potency-Replicate_1 7.6489qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway - cell viability counter screen [AID743064, Type: confirmatory]
View
6
[SID144208203]
Potency-Replicate_1 8.5823qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway [AID743065, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
View
7
[SID144208203]
Potency-Replicate_1 9.6295qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
View
8
[SID103282386]
ED50 10Induction of morphological transformation of rat ASK cells into astrocytes after 1 hr by light microscopy [AID334311, Type: Literature]
View
9
[SID144208203]
Potency-Replicate_1 12.1228qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
View
10
[SID144208203]
Ratio Potency (uM) 12.2276qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway: Summary [AID743077, Type: summary]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
View
11
[SID144208203]
Potency-Replicate_1 12.2336qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway [AID743035, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
View
12
[SID144208203]
Potency-Replicate_1 12.2336qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway - cell viability counter screen [AID743211, Type: confirmatory]
View
13
[SID144208203]
Potency-Replicate_1 13.602qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
View
14
[SID144208203]
Potency-Replicate_1 13.7263qHTS assay to identify small molecule antagonists of the vitamin D receptor (VDR) signaling pathway - cell viability counter screen [AID743225, Type: confirmatory]
View
15
[SID144208203]
Potency-Replicate_1 15.2617qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
View
16
[SID144208203]
Potency-Replicate_1 15.2617qHTS assay to identify aromatase inhibitors [AID743083, Type: confirmatory]cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a [Homo sapiens] [gi:119597822]
View
17
[SID144208203]
Potency-Replicate_1 15.4012qHTS assay to identify small molecule agonists of the vitamin D receptor (VDR) signaling pathway - cell viability counter screen [AID743224, Type: confirmatory]
View
18
[SID144208203]
Potency-Replicate_1 21.7547qHTS assay to identify small molecule agonists of the farnesoid-X-receptor (FXR) signaling pathway - cell viability counter screen [AID743218, Type: confirmatory]
View
19
[SID144208203]
Potency-Replicate_1 21.7547qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway - cell viability counter screen [AID743033, Type: confirmatory]
View
20
[SID17388687]
Potency 22.3872qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1) [AID1030, Type: confirmatory]aldehyde dehydrogenase 1 family, member A1 [Homo sapiens] [gi:30582681]
View