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Retinaldehyde (CID 638015) - Compound BioActivity Data
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BioActivity Outcomes:
Active(222)
 
 
Inactive(96)
 
 
Inconclusive(114)
 
 
Unspecified(16)
 
 
Top Targets:
NR LBD PPAR(13)
 
 
 
 
NR LBD ER(9)
 
 
 
NR LBD AR(9)
 
 
 
 
NR LBD TR(7)
 
 
 
 
NR LBD VDR(6)
 
 
 
BioAssay Types:
Confirmatory(213)
 
 
 
 
Summary(24)
 
 
 
 
Literature(18)
 
 
 
 
BioActivity Types:
Potency(193)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 274    Data Row: 448   Total Pages: 9   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID17388687]
Potency 0.4216qHTS assay to identify small molecules that stimulate interleukin-8 (IL-8) secretion [AID651758, Type: confirmatory]interleukin 8 [Homo sapiens] [gi:186368]
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2
[SID17388687]
Potency-Replicate_1 7.0795qHTS assay for small molecule activators of the human pregnane X receptor (PXR) signaling pathway [AID720659, Type: confirmatory]pregnane X nuclear receptor [Homo sapiens] [gi:325495557]
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3
[SID144208203]
Potency-Replicate_1 7.6489qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway - cell viability counter screen [AID743064, Type: confirmatory]
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4
[SID144208203]
Potency-Replicate_1 8.5823qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway [AID743065, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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5
[SID144208203]
Potency-Replicate_1 9.6295qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
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6
[SID103282386]
ED50 10Induction of morphological transformation of rat ASK cells into astrocytes after 1 hr by light microscopy [AID334311, Type: Literature]
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7
[SID144208203]
Potency-Replicate_1 12.1228qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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8
[SID144208203]
Ratio Potency (uM) 12.2276qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway: Summary [AID743077, Type: summary]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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9
[SID144208203]
Potency-Replicate_1 12.2336qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway - cell viability counter screen [AID743211, Type: confirmatory]
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10
[SID144208203]
Potency-Replicate_1 12.2336qHTS assay to identify small molecule antagonists of the farnesoid-X-receptor (FXR) signaling pathway - cell viability counter screen [AID743221, Type: confirmatory]
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11
[SID144208203]
Potency-Replicate_1 12.2336qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway [AID743035, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
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12
[SID144208203]
Potency-Replicate_1 13.602qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
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13
[SID144208203]
Potency-Replicate_1 13.7263qHTS assay to identify small molecule antagonists of the vitamin D receptor (VDR) signaling pathway - cell viability counter screen [AID743225, Type: confirmatory]
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14
[SID144208203]
Potency-Replicate_1 15.2617qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
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15
[SID144208203]
Potency-Replicate_1 15.2617qHTS assay to identify aromatase inhibitors [AID743083, Type: confirmatory]cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a [Homo sapiens] [gi:119597822]
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16
[SID144208203]
Potency-Replicate_1 15.4012qHTS assay to identify small molecule agonists of the vitamin D receptor (VDR) signaling pathway - cell viability counter screen [AID743224, Type: confirmatory]
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17
[SID144208203]
Potency-Replicate_1 19.3889qHTS assay to identify small molecule agonists of the farnesoid-X-receptor (FXR) signaling pathway - cell viability counter screen [AID743218, Type: confirmatory]
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18
[SID144208203]
Potency-Replicate_1 19.3889qHTS assay for small molecule activators of the heat shock response signaling pathway - cell viability counter screen [AID743209, Type: confirmatory]
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19
[SID144208203]
Potency-Replicate_1 19.3889qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor gamma (PPARg) signaling pathway - cell viability counter screen [AID743194, Type: confirmatory]
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20
[SID144208203]
Potency-Replicate_1 21.7547qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway - cell viability counter screen [AID743033, Type: confirmatory]
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21
[SID17388687]
Potency 22.3872qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1) [AID1030, Type: confirmatory]aldehyde dehydrogenase 1 family, member A1 [Homo sapiens] [gi:30582681]
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22
[SID144208203]
Potency-Replicate_1 24.4092qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway - cell viability counter screen [AID743213, Type: confirmatory]
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23
[SID144208203]
Potency-Replicate_1 24.4092qHTS assay to identify small molecule antagonists of the glucocorticoid receptor (GR) signaling pathway - cell viability counter screen [AID720693, Type: confirmatory]
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24
[SID17388687]
Potency 29.8493qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway [AID651741, Type: confirmatory]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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25
[SID144208203]
Potency-Replicate_1 30.451qHTS assay to identify aromatase inhibitors - cell viability counter screen [AID743084, Type: confirmatory]
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26
[SID17388687]
Potency 31.6228MultiTox-Fluor Cytotoxicity Assay - LYMP1-002 - Dead Cells [AID960, Type: confirmatory]
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27
[SID17388687]
Potency 31.6228Cell Viability - LYMP2-010 [AID981, Type: confirmatory]
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28
[SID17388687]
Potency 39.8107Cell Viability - LYMP2-004 [AID966, Type: confirmatory]
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29
[SID17388687]
Potency 39.8107Cell Viability - LYMP2-005 [AID967, Type: confirmatory]
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30
[SID17388687]
Potency 39.8107Cell Viability - LYMP2-009 [AID968, Type: confirmatory]
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31
[SID17388687]
Potency 39.8107Cell Viability - LYMP2-015 [AID971, Type: confirmatory]
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32
[SID17388687]
Potency 39.8107Cell Viability - LYMP2-017 [AID972, Type: confirmatory]
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33
[SID17388687]
Potency 39.8107Cell Viability - LYMP2-007 [AID979, Type: confirmatory]
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34
[SID17388687]
Potency 39.8107Cell Viability - LYMP2-008 [AID980, Type: confirmatory]
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35
[SID17388687]
Potency 39.8107Cell Viability - LYMP2-018 [AID985, Type: confirmatory]
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36
[SID17388687]
Potency 39.8107Cell Viability - LYMP2-022 [AID987, Type: confirmatory]
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37
[SID17388687]
Potency 39.8107Cell Viability - LYMP2-024 [AID988, Type: confirmatory]
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38
[SID17388687]
Potency 39.8107Cell Viability - LYMP2-001 [AID921, Type: confirmatory]
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39
[SID144208203]
Potency-Replicate_1 43.0132qHTS assay for small molecule agonists of the p53 signaling pathway - cell viability [AID651633, Type: confirmatory]
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40
[SID17388687]
Potency 44.6684qHTS assay for small molecule antagonists of estrogen receptor alpha signaling [AID588513, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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41
[SID144208203]
Potency-Replicate_1 48.7027qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway [AID743075, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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42
[SID17388687]
Potency 50.1187qHTS assay for cell viability of the p53RE-bla HCT-116 cell line [AID743292, Type: confirmatory]
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43
[SID17388687]
Potency 50.1187Cell Viability - LYMP2-026 [AID989, Type: confirmatory]
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44
[SID17388687]
Potency 50.1187Cell Viability - LYMP1-002 - Assay at 24 hr [AID993, Type: confirmatory]
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45
[SID17388687]
Potency 50.1187Cell Viability - LYMP1-002 - Assay at 40 hr [AID994, Type: confirmatory]
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46
[SID17388687]
Potency 50.1187Cell Viability - LYMP2-019 [AID973, Type: confirmatory]
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47
[SID17388687]
Potency 50.1187Cell Viability - LYMP2-021 [AID974, Type: confirmatory]
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48
[SID17388687]
Potency 50.1187Cell Viability - LYMP2-023 [AID975, Type: confirmatory]
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49
[SID17388687]
Potency 50.1187Cell Viability - LYMP2-012 [AID982, Type: confirmatory]
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50
[SID17388687]
Potency 50.1187Cell Viability - LYMP2-014 [AID983, Type: confirmatory]
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