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sinapinic acid (CID 637775) - Compound BioActivity Data
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BioActivity Outcomes:
Active(9)
 
 
Inactive(449)
 
 
Unspecified(20)
 
 
Top Targets:
7TM GPCR Srx(14)
 
 
7TM GPCR Srsx(11)
 
 
TRP 2(5)
 
 
CAP ED(5)
 
 
Troponin(4)
 
 
BioAssay Types:
Screening(347)
 
 
 
Confirmatory(87)
 
 
 
Literature(34)
 
 
 
 
BioActivity Types:
Potency(70)
 
 
 
IC50(21)
 
 
 
 
EC50(2)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 436    Data Row: 478   Total Pages: 24   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103330747]
IC50 4.77Inhibition of lipid peroxidation in Sprague-Dawley rat brain after 30 mins by TBARS assay [AID314540, Type: Literature]
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2
[SID103330747]
IC50 25.7DPPH radical scavenging activity after 180 mins [AID382837, Type: Literature]
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3
[SID103330747]
IC50 28Inhibition of COX2 after 5 mins by spectrophotometric analysis [AID652655, Type: Literature]
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4
[SID103330747]
IC50 39.2Inhibition of COX1 after 5 mins by spectrophotometric analysis [AID652654, Type: Literature]
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5
[SID47193735]
HTS for Identification of VLA-4 Allosteric Modulators from MLPCN library [AID2557, Type: screening]integrin alpha-4 precursor [Homo sapiens] [gi:67191027]
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6
[SID47193735]
HTS to identify compounds that promote myeloid differentiation with MLPCN compound set [AID624256, Type: screening] [geneid:3205]
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7
[SID47193735]
Counterscreen for activators of kallikrein-7 (K7) zymogen: Fluorescence intensity-based biochemical high throughput counterscreen assay for activators that optically interfere with measurement of EDANS-DABCYL fluorescence [AID686952, Type: screening]
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8
[SID47193735]
Fluorescence Intensity-based biochemical primary high throughput confirmation assay to identify activators of kallikrein-7 (K7) zymogen [AID686949, Type: screening]kallikrein-7 isoform 1 preproprotein [Homo sapiens] [gi:21327705]
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9
[SID47193735]
Fluorescence Intensity-based biochemical primary high throughput screening assay to identify activators of kallikrein-7 (K7) zymogen [AID652039, Type: screening]kallikrein-7 isoform 1 preproprotein [Homo sapiens] [gi:21327705]
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10
[SID103330747]
IC50 66Antioxidant activity assessed as residual DPPH radical scavenging activity after 45 mins by spectrophotometrically [AID568834, Type: Literature]
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11
[SID103330747]
IC50 100Inhibitory concentration of compound on nitric oxide (NO) production in lipopolysaccharide activated mouse peritoneal macrophages [AID248765, Type: Literature]
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12
[SID103330747]
EC50 250Antioxidant activity assessed as DPPH radical scavenging activity by spectrophotometry [AID590194, Type: Literature]
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13
[SID103330747]
IC50 351Inhibition of mushroom tyrosinase after 25 mins by spectrophotometry [AID590195, Type: Literature]Polyphenol oxidase 2 [gi:6686057]
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14
[SID103330747]
Antioxidant activity against Cu2+-induced lipid peroxidation in human plasma LDL preincubated for 1 hr before Cu2+ challenge [AID397153, Type: Literature]
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15
[SID103330747]
DPPH radical scavenging activity assessed as Trolox equivalent antioxidant capacity at 50 uM after 40 mins [AID397183, Type: Literature]
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16
[SID103330747]
ABTS radical scavenging activity assessed as Trolox equivalent antioxidant capacity at 50 uM by spectrophotometric analysis [AID397184, Type: Literature]
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17
[SID103330747]
Percent inhibition of nitric oxide (NO) production in lipopolysaccharide activated mouse peritoneal macrophages at 100 uM of compound [AID252044, Type: Literature]
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18
[SID103330747]
Percentage inhibition against release of beta-hexosaminidase from RBL-2H3 cells at 100 uM from control [AID166551, Type: Literature]
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19
[SID103330747]
Inhibitory activity of compound was tested against peroxinitrite in collagen type I at concentration 100 uM of each sample was treated with 1.0 mM peroxynitrite [AID219712, Type: Literature]
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20
[SID103330747]
Inhibitory activity of compound was tested against peroxinitrite in collagen type I with concentration 50 uM of each sample was treated with 1.0 mM peroxynitrite [AID219713, Type: Literature]
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