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geraniol (CID 637566) - Compound BioActivity Data
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BioActivity Outcomes:
Active(5)
 
 
Inactive(580)
 
 
Inconclusive(58)
 
 
Unspecified(178)
 
 
Top Targets:
NR LBD PPAR(29)
 
 
 
p450(25)
 
 
 
 
NR LBD ER(25)
 
 
 
 
NR LBD AR(24)
 
 
 
 
NR LBD GR(17)
 
 
 
 
BioAssay Types:
Confirmatory(437)
 
 
 
 
 
Literature(95)
 
 
 
 
Summary(72)
 
 
 
 
Screening(9)
 
 
BioActivity Types:
Potency(403)
 
 
 
 
IC50(117)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 521    Data Row: 821   Total Pages: 17   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144209584]
Potency-Replicate_1 2.2183qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway [AID743075, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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2
[SID144209584]
Ratio Potency (uM) 4.9662qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway: Summary [AID743077, Type: summary]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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3
[SID26748503]
Potency 7.9433qHTS Assay for Inhibitors of 15-hLO (15-human lipoxygenase) [AID887, Type: confirmatory]15-lipoxygenase [Homo sapiens] [gi:1832253]
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4
[SID144209584]
Potency-Replicate_1 31.0746qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line [AID743079, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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5
[SID8149728]
Screen for compounds that suppress mutant SOD1-mediated cell death (mSODtox) [AID1601, Type: other]
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6
[SID103193982]
IC50 52Antiplasmodial activity after 48 hrs against chloroquine-resistant Plasmodium falciparum FcM29-Cameroon by [3H]hypoxanthine uptake [AID302171, Type: Literature]
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7
[SID103193982]
Antifungal activity against Candida albicans ATCC 90028 after 48 hrs [AID302172, Type: Literature]
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8
[SID103193982]
Antifungal activity against Candida albicans ATCC 90028 after 24 hrs [AID302173, Type: Literature]
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9
[SID103193982]
Antimicrobial activity Propionibacterium acnes ATCC 11827 after 2 days by broth dilution method [AID332912, Type: Literature]
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10
[SID103193982]
Antimicrobial activity against Bacillus subtilis ATCC 9372 after 2 days by twofold serial broth dilution method [AID334989, Type: Literature]
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11
[SID103193982]
Antimicrobial activity against Brevibacterium ammoniagenes ATCC 6872 after 2 days by twofold serial broth dilution method [AID334990, Type: Literature]
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12
[SID103193982]
Antimicrobial activity against Propionibacterium acnes ATCC 11827 after 2 days by twofold serial broth dilution method [AID334991, Type: Literature]
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13
[SID103193982]
Antimicrobial activity against Staphylococcus aureus ATCC 12598 after 2 days by twofold serial broth dilution method [AID334992, Type: Literature]
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14
[SID103193982]
Antimicrobial activity against Streptococcus mutans ATCC 25175 after 2 days by twofold serial broth dilution method [AID334993, Type: Literature]
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15
[SID103193982]
Antimicrobial activity against Escherichia coli ATCC 9637 after 2 days by twofold serial broth dilution method [AID334994, Type: Literature]
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16
[SID103193982]
Antimicrobial activity against Pseudomonas aeruginosa ATCC 10145 after 2 days by twofold serial broth dilution method [AID334995, Type: Literature]
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17
[SID103193982]
Antimicrobial activity against Enterobacter aerogenes ATCC 13048 after 2 days by twofold serial broth dilution method [AID334996, Type: Literature]
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18
[SID103193982]
Antimicrobial activity against Saccharomyces cerevisiae ATCC 7754 after 2 days by twofold serial broth dilution method [AID334997, Type: Literature]
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19
[SID103193982]
Antimicrobial activity against Candida utilis ATCC 9226 after 2 days by twofold serial broth dilution method [AID334998, Type: Literature]
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20
[SID103193982]
Antimicrobial activity against Pityrosporum ovale ATCC 14521 by twofold serial broth dilution method [AID334999, Type: Literature]
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21
[SID103193982]
Antimicrobial activity against Penicillium chrysogenum ATCC 10106 after 5 days by twofold serial broth dilution method [AID335000, Type: Literature]
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22
[SID103193982]
Acaricidal activity against Psoroptes cuniculi at 1% dilution in physiological saline after 48 hrs by direct contact assay [AID338297, Type: Literature]
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23
[SID103193982]
Acaricidal activity against Psoroptes cuniculi at 0.25% dilution in physiological saline after 48 hrs by direct contact assay [AID338298, Type: Literature]
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24
[SID103193982]
Acaricidal activity against Psoroptes cuniculi at 0.125% dilution in physiological saline after 48 hrs by direct contact assay [AID338299, Type: Literature]
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25
[SID103193982]
Acaricidal activity against Psoroptes cuniculi at 6 uL after 24 hrs by inhalation assay [AID338300, Type: Literature]
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26
[SID103193982]
Acaricidal activity against Psoroptes cuniculi at 3 uL after 24 hrs by inhalation assay [AID338301, Type: Literature]
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27
[SID103193982]
Acaricidal activity against Psoroptes cuniculi at 1 uL after 24 hrs by inhalation assay [AID338302, Type: Literature]
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28
[SID103193982]
Antiproliferative activity against human PC3 cells assessed as reduction of cell viability after 72 hrs by WST-1 assay relative to control [AID344007, Type: Literature]
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29
[SID103193982]
IC50 DRUGMATRIX: Nicotinic Acetylcholine radioligand binding (ligand: [125I] Epibatidine) [AID625158, Type: other]
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30
[SID103193982]
DRUGMATRIX: Phorbol Ester radioligand binding (ligand: [3H] PDBu) [AID625164, Type: other]
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31
[SID103193982]
IC50 DRUGMATRIX: Phosphodiesterase PDE3 enzyme inhibition (substrate: [3H]cAMP + cAMP) [AID625165, Type: other]
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32
[SID103193982]
IC50 DRUGMATRIX: Phosphodiesterase PDE4 enzyme inhibition (substrate: [3H]cAMP + cAMP) [AID625166, Type: other]
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33
[SID103193982]
DRUGMATRIX: Platelet-Derived Growth Factor (PDGF) radioligand binding (ligand: [125I] PDGF) [AID625169, Type: other]
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34
[SID103193982]
IC50 DRUGMATRIX: Potassium Channel [KATP] radioligand binding (ligand: [3H] Glyburide) [AID625170, Type: other]
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35
[SID103193982]
DRUGMATRIX: Purinergic P2X radioligand binding (ligand: [3H] alpha, beta-Methylene-ATP) [AID625189, Type: other]
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36
[SID103193982]
IC50 DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT1A radioligand binding (ligand: [3H] 8-OH-DPAT) [AID625190, Type: other]
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37
[SID103193982]
IC50 DRUGMATRIX: Sodium/nucleoside co-transporter radioligand binding (ligand: nitrobenzylthioinosine) [AID625197, Type: other]
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38
[SID103193982]
IC50 DRUGMATRIX: ATPase, Na+/K+ enzyme inhibition (substrate: ATP) [AID625210, Type: other]
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39
[SID103193982]
DRUGMATRIX: Atrial Natriuretic Factor (ANF) radioligand binding (ligand: [125I] ANF (rat)) [AID625211, Type: other]
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40
[SID103193982]
IC50 DRUGMATRIX: beta-Lactamase enzyme inhibition (substrate: Nitrocefin) [AID625212, Type: other]
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41
[SID103193982]
IC50 DRUGMATRIX: Calcium Channel Type L, Benzothiazepine radioligand binding (ligand: [3H] Diltiazem) [AID625215, Type: other]
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42
[SID103193982]
IC50 DRUGMATRIX: Calcium Channel Type L, Dihydropyridine radioligand binding (ligand: [3H] Nitrendipine) [AID625216, Type: other]
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43
[SID103193982]
IC50 DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT3 radioligand binding (ligand: [3H] GR-65630) [AID625219, Type: other]
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44
[SID103193982]
IC50 DRUGMATRIX: Sigma2 radioligand binding (ligand: [3H] Ifenprodil) [AID625224, Type: other]
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45
[SID103193982]
IC50 DRUGMATRIX: Sodium Channel, Site 2 radioligand binding (ligand: [3H] Batrachotoxin) [AID625225, Type: other]
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46
[SID103193982]
DRUGMATRIX: Tumor Necrosis Factor (TNF), Non-Selective radioligand binding (ligand: [125I] TNF-alpha) [AID625230, Type: other]
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47
[SID103193982]
IC50 DRUGMATRIX: Calcium Channel Type L, Phenylalkylamine radioligand binding (ligand: [3H] (-)-Desmethoxyverapamil (D-888)) [AID625234, Type: other]
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48
[SID103193982]
IC50 DRUGMATRIX: GABAA, Muscimol, Central radioligand binding (ligand: [3H] Muscimol) [AID625260, Type: other]
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49
[SID103193982]
IC50 DRUGMATRIX: GABAA, Flunitrazepam, Central radioligand binding (ligand: [3H] Flunitrazepam) [AID625261, Type: other]
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50
[SID103193982]
IC50 DRUGMATRIX: GABAA, Chloride Channel, TBOB radioligand binding (ligand: [3H] TBOB) [AID625262, Type: other]
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