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BioActivity Data for Compound geraniol (CID 637566)

BioActivity Outcomes:
Active(7)
 
 
Inactive(638)
 
 
Inconclusive(53)
 
 
Unspecified(372)
 
 
Top Targets:
7tm 4(32)
 
 
 
NR LBD PPAR(29)
 
 
 
p450(25)
 
 
 
 
NR LBD ER(25)
 
 
 
 
NR LBD AR(24)
 
 
 
BioAssay Types:
Confirmatory(578)
 
 
 
 
 
Literature(162)
 
 
 
 
 
Summary(78)
 
 
 
 
Screening(17)
 
 
BioAssay Categories:
In vitro(134)
 
 
 
In vivo(142)
 
 
 
Biochemical(136)
 
 
 
 
Toxicity(176)
 
 
 
 
ADME(1)
 
 
Cell-based(97)
 
 
 
 
Organism-base..(2)
 
 
BioActivity Types:
Potency(428)
 
 
 
 
IC50(117)
 
 
AC50(6)
 
 
 
EC50(1)
 
 
Ki(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 754    Data Row: 1070   Total Pages: 54   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144209584]
Potency-Replicate_1 2.2183qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway [AID743075, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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2
[SID144209584]
Ratio Potency (uM) 4.9662qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway: Summary [AID743077, Type: summary]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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3
[SID26748503]
Potency 7.9433qHTS Assay for Inhibitors of 15-hLO (15-human lipoxygenase) [AID887, Type: confirmatory]15-lipoxygenase, partial [Homo sapiens] [gi:1832253]
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4
[SID144209584]
Potency-Replicate_1 31.0746qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line [AID743079, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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5
[SID103193982]
Reversible inhibition of Electrophorus electricus (electric eel)acetylcholinesterase (AChE) using acetylthiocholine iodide substrate by Ellman method based colorimetry [AID1098340, Type: Literature]Acetylcholinesterase [gi:14916521]
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6
[SID103193982]
Competitive inhibition of Electrophorus electricus (electric eel) acetylcholinesterase (AChE) using acetylthiocholine iodide substrate by Ellman method based colorimetry [AID1098341, Type: Literature]Acetylcholinesterase [gi:14916521]
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7
[SID8149728]
Screen for compounds that suppress mutant SOD1-mediated cell death (mSODtox) [AID1601, Type: other]
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8
[SID103193982]
IC50 52Antiplasmodial activity after 48 hrs against chloroquine-resistant Plasmodium falciparum FcM29-Cameroon by [3H]hypoxanthine uptake [AID302171, Type: Literature]
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9
[SID103193982]
Ki 100Inhibition of Electrophorus electricus (electric eel) acetylcholinesterase (AChE) using acetylthiocholine iodide substrate by Ellman method based colorimetry [AID1098346, Type: Literature]Acetylcholinesterase [gi:14916521]
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10
[SID103193982]
IC50 DRUGMATRIX: Protein Serine/Threonine Kinase, p38alpha enzyme inhibition (substrate: Myelin Basic Protein) [AID625182, Type: confirmatory]Mitogen-activated protein kinase 14 [gi:2499600]
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11
[SID103193982]
IC50 DRUGMATRIX: Estrogen ERbeta radioligand binding (ligand: [3H] Estradiol) [AID625259, Type: confirmatory]Estrogen receptor beta [gi:6166154]
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12
[SID103193982]
IC50 DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT4 radioligand binding (ligand: [3H] GR-113808) [AID625220, Type: confirmatory]5-hydroxytryptamine receptor 4 [gi:6224984]
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13
[SID103193982]
IC50 DRUGMATRIX: CYP450, 2C9 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin) [AID625248, Type: confirmatory]Cytochrome P450 2C9 [gi:6686268]
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14
[SID103193982]
IC50 DRUGMATRIX: Cysteinyl leukotriene receptor 1 radioligand binding (ligand: [3H]LTD4) [AID625145, Type: confirmatory]Cysteinyl leukotriene receptor 1 [gi:20138087]
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15
[SID103193982]
IC50 DRUGMATRIX: Adrenergic Alpha-2C radioligand binding (ligand: [3H] MK-912) [AID625203, Type: confirmatory]Alpha-2C adrenergic receptor [gi:20141211]
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16
[SID103193982]
IC50 DRUGMATRIX: Muscarinic M4 radioligand binding (ligand: [3H] N-Methylscopolamine) [AID625154, Type: confirmatory]Muscarinic acetylcholine receptor M4 [gi:23503039]
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17
[SID103193982]
IC50 DRUGMATRIX: Cyclooxygenase COX-2 enzyme inhibition (substrate: Arachidonic acid) [AID625244, Type: confirmatory]Prostaglandin G/H synthase 2 [gi:3915797]
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18
[SID103193982]
IC50 DRUGMATRIX: Potassium Channel HERG radioligand binding (ligand: [3H] Astemizole) [AID625171, Type: confirmatory]Potassium voltage-gated channel subfamily H member 2 [gi:7531135]
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19
[SID103193982]
DRUGMATRIX: Protein Tyrosine Phosphatase, PTPRC (CD45) enzyme inhibition (substrate: DiFMUP) [AID625188, Type: other]Receptor-type tyrosine-protein phosphatase C [gi:33112650]
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20
[SID103193982]
IC50 DRUGMATRIX: Adrenergic beta1 radioligand binding (ligand: [125I] Cyanopindolol) [AID625204, Type: confirmatory]Beta-1 adrenergic receptor [gi:48429211]
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