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anethole (CID 637563) - Compound BioActivity Data
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BioActivity Outcomes:
Active(13)
 
 
Inactive(252)
 
 
Inconclusive(15)
 
 
Unspecified(36)
 
 
Top Targets:
NR LBD PPAR(16)
 
 
 
NR LBD AR(14)
 
 
 
NR LBD ER(14)
 
 
 
NR LBD VDR(9)
 
 
NR LBD GR(8)
 
 
 
BioAssay Types:
Confirmatory(174)
 
 
 
Literature(57)
 
 
 
 
Summary(48)
 
 
 
Screening(4)
 
 
BioActivity Types:
Potency(207)
 
 
 
Ki(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 222    Data Row: 316   Total Pages: 16   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103581525]
Antimetastatic activity in human DU145 cells assessed as decrease of snail mRNA expression at 25 to 100 uM by RT-PCR analysis [AID1063008, Type: Literature]
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2
[SID103581525]
Antimetastatic activity in human DU145 cells assessed as decrease of twist mRNA expression at 25 to 100 uM by RT-PCR analysis [AID1063009, Type: Literature]
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3
[SID103581525]
Antimetastatic activity in human DU145 cells assessed as decrease of vimentin mRNA expression at 25 to 100 uM by RT-PCR analysis [AID1063010, Type: Literature]
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4
[SID103581525]
Antimetastatic activity in human DU145 cells assessed as increase of E-cadherin mRNA expression at 25 to 100 uM by RT-PCR analysis [AID1063011, Type: Literature]
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5
[SID103581525]
Antimetastatic activity in human DU145 cells assessed as decrease of twist expression at 25 to 100 uM by Western blotting [AID1063012, Type: Literature]
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6
[SID103581525]
Antimetastatic activity in human DU145 cells assessed as decrease of vimentin expression at 25 to 100 uM by Western blotting [AID1063013, Type: Literature]
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7
[SID103581525]
Antimetastatic activity in human DU145 cells assessed as increase of E-cadherin expression at 25 to 100 uM by Western blotting [AID1063014, Type: Literature]
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8
[SID103581525]
Antimigratory activity in human DU145 cells at 100 uM by wound-healing assay [AID1063015, Type: Literature]
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9
[SID103581525]
Antiinvasive activity in human DU145 cells assessed as reduction of number of invaded cells through matrigel at 25 to 100 uM after 8 hrs by Boyden chamber invasion assay [AID1063016, Type: Literature]
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10
[SID103581525]
Inhibition of cell adhesion in human DU145 cells in vitronectin-coated plates at 25 to 100 uM [AID1063017, Type: Literature]
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11
[SID103581525]
Drug excretion in 80 last instar Trichoplusia ni (cabbage looper) larvae feces assessed as side chain methyl group hydroxylated compound on at 0.1 % fwt, po by 1H/13C NMR analysis [AID1103165, Type: Literature]
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12
[SID103581525]
Reversible inhibition of Electrophorus electricus (electric eel)acetylcholinesterase (AChE) using acetylthiocholine iodide substrate by Ellman method based colorimetry [AID1098340, Type: Literature]Acetylcholinesterase [gi:14916521]
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13
[SID103581525]
Antimetastatic activity in human DU145 cells assessed as decrease of MMP9 mRNA expression at 25 to 100 uM by RT-PCR analysis [AID1063006, Type: Literature]
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14
[SID103581525]
Antimetastatic activity in human DU145 cells assessed as decrease of PI3K/Akt expression by Western blotting [AID1063007, Type: Literature]
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15
[SID103581525]
Inhibition of MMP9 in human DU145 cells after 24 hrs by SDS-PAGE gelatin zymography assay [AID1063005, Type: Literature]Matrix metalloproteinase-9 [gi:269849668]
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16
[SID103581525]
Inhibition of sodium fluorescein uptake in OATP1B1-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM [AID977599, Type: Literature]
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17
[SID103581525]
Inhibition of sodium fluorescein uptake in OATP1B3-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM [AID977602, Type: Literature]
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18
[SID103581525]
Cytotoxicity against human DU145 cells assessed as cell viability up to 200 uM after 24 hrs by MTT assay [AID1063018, Type: Literature]
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19
[SID103581525]
Nematicidal activity against Meloidogyne incognita J2 (root-knot nematode) larvae immersed in compound solution for 24 hr assessed as reduction in larval motility [AID1081538, Type: Literature]
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20
[SID103581525]
Nematicidal activity against Meloidogyne incognita J2 (root-knot nematode) larvae immersed in compound solution for 48 hr assessed as reduction in larval motility [AID1081539, Type: Literature]
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