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cinnamic aldehyde (CID 637511) - Compound BioActivity Data
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BioActivity Outcomes:
Active(17)
 
 
Inactive(1025)
 
 
Inconclusive(43)
 
 
Unspecified(165)
 
 
Top Targets:
7TM GPCR Srx(31)
 
 
 
7TM GPCR Srsx(29)
 
 
 
NR LBD ER(29)
 
 
 
 
 
NR LBD PPAR(28)
 
 
 
NR LBD AR(26)
 
 
 
 
 
BioAssay Types:
Confirmatory(746)
 
 
 
 
 
Screening(273)
 
 
 
Literature(116)
 
 
 
 
 
Summary(63)
 
 
 
 
BioActivity Types:
Potency(595)
 
 
 
 
 
IC50(129)
 
 
 
 
EC50(3)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 789    Data Row: 1250   Total Pages: 63   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID17389103]
Potency 2.5119qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1) [AID1030, Type: confirmatory]aldehyde dehydrogenase 1 family, member A1 [Homo sapiens] [gi:30582681]
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2
[SID103239041]
EC50 6.5Activation of TRPA1 channel expressed in CHO cells assessed as increase in intracellular calcium levels [AID482140, Type: Literature]
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3
[SID144204695]
Potency-Replicate_1 11.8832qHTS assay to identify small molecule agonists of the androgen receptor (AR) signaling pathway using the MDA cell line [AID743040, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
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4
[SID17389104]
Potency 12.5893qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1) [AID1030, Type: confirmatory]aldehyde dehydrogenase 1 family, member A1 [Homo sapiens] [gi:30582681]
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5
[SID144204695]
Ratio Potency (uM) 18.9959qHTS assay to identify small molecule agonists of the androgen receptor (AR) signaling pathway: Summary [AID743053, Type: summary]AR protein [Homo sapiens] [gi:124375976]
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6
[SID103239041]
EC50 19Activation of TRPA1 [AID329099, Type: Literature]
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7
[SID103239041]
IC50 43Inhibition of NF-kappaB transfected in LPS-stimulated mouse RAW264.7 cells [AID349484, Type: Literature]
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8
[SID144213588]
Potency-Replicate_1 61.1306qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line [AID743079, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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9
[SID29215112]
A qHTS for Small Molecule Inhibitors of Shiga Toxin [AID2315, Type: screening]shiga toxin 1 variant A subunit [Escherichia coli O157:H7] [gi:32400299]
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10
[SID29215112]
A qHTS for Small Molecule Inhibitors of Shiga Toxin [AID2315, Type: screening]shiga toxin 1 B subunit [Escherichia coli O157:H7] [gi:32400300]
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11
[SID103239041]
Inhibition of NFATc1 expression in RANKL-stimulated mouse RAW264.7 cells after 48 hrs by immunoblotting [AID349478, Type: Literature]
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12
[SID103239041]
Inhibition of multinucleated cell formation in RANKL-stimulated mouse RAW264.7 cells at 0.5 to 2 uM after 3 days by TRAP staining [AID349479, Type: Literature]
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13
[SID103239041]
Inhibition of bone resorption by mature osteoclast in RANKL-stimulated mouse RAW264.7 cells pretreated for 1 hr measured after 8 days [AID349480, Type: Literature]
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14
[SID17389103]
Cell Viability - NIH 3T3 [AID541, Type: confirmatory]
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15
[SID17389104]
Cell Viability - NIH 3T3 [AID541, Type: confirmatory]
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16
[SID103239041]
Agonist activity at TRPA1 [AID500219, Type: Literature]
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17
[SID103239041]
Inhibition of Wnt/beta-catenin (unknown origin) signaling pathway expressed in HEK293 cells assessed as inhibition of TCF4 transcriptional activity at 5 to 40 uM after 24 hrs by TOPflash reporter gene assay [AID762798, Type: Literature]
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18
[SID103239041]
EC50 51.4Agonist activity at human TRPA1 expressed in HEK293 cells assessed as [45]Ca2+ influx by microbeta plate count [AID452237, Type: Literature]Transient receptor potential cation channel subfamily A member 1 [gi:313104269]
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19
[SID103239041]
IC50 245Inhibition of COX2 [AID403340, Type: Literature]
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20
[SID103239041]
IC50 520Inhibition of mushroom tyrosinase after 10 mins by spectrophotometry [AID467606, Type: Literature]Polyphenol oxidase 2 [gi:6686057]
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