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Tenatoprazole (CID 636411) - Compound BioActivity Data
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BioActivity Outcomes:
Active(35)
 
 
Inactive(112)
 
 
Inconclusive(44)
 
 
Unspecified(7)
 
 
Top Targets:
NR LBD PPAR(8)
 
 
 
NR LBD AR(7)
 
 
 
NR LBD ER(7)
 
 
 
NR LBD VDR(5)
 
 
 
NR LBD Fxr(4)
 
 
BioAssay Types:
Confirmatory(97)
 
 
 
 
Literature(71)
 
 
 
 
 
Summary(24)
 
 
 
 
Screening(2)
 
 
BioActivity Types:
Potency(114)
 
 
 
 
IC50(6)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 135    Data Row: 198   Total Pages: 10   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID160693324]
IC50 0.224HARVARD: Inhibition of liver stage Plasmodium berghei infection in HepG2 cells [AID685501, Type: Literature]
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2
[SID160693324]
IC50 1.8Inhibition of mouse Ido2 transfected in HEK293T cells using L-tryptophan as substrate assessed as kynurenine formation after 45 mins by spectrophotometric analysis [AID717845, Type: Literature]Indoleamine 2,3-dioxygenase 2 [gi:408360141]
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3
[SID50112774]
Potency 8.4921Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation [AID504834, Type: confirmatory]
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4
[SID50112774]
Potency 9.5283Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation [AID504832, Type: confirmatory]
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5
[SID170465931]
Potency-Replicate_1 10.5901qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway [AID743202, Type: confirmatory]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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6
[SID170465931]
Ratio Potency (uM) 14.3957qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway: Summary [AID743219, Type: summary]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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7
[SID50112774]
Potency 18.6892Confirmation qHTS Assay for Inhibitors of Bacillus subtilis Sfp phosphopantetheinyl transferase (PPTase) [AID2701, Type: confirmatory]phosphopantetheinyl transferase [Bacillus subtilis] [gi:10954339]
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8
[SID144206071]
Potency-Replicate_1 26.6032qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway [AID743085, Type: confirmatory]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
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9
[SID144206071]
Potency 26.6086qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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10
[SID144206071]
AhR Potency (uM) 28.1796qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway: Summary [AID743122, Type: summary]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
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11
[SID144206071]
Potency-Replicate_1 29.8493qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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12
[SID144206071]
Potency-Replicate_1 29.8493qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
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13
[SID50112774]
Potency 44.6684Inhibitors of the vitamin D receptor (VDR): qHTS [AID504847, Type: confirmatory]vitamin D3 receptor isoform VDRA [Homo sapiens] [gi:63054845]
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14
[SID50112774]
Potency 44.6684qHTS Assay for Inhibitors of Bacillus subtilis Sfp phosphopantetheinyl transferase (PPTase) [AID1490, Type: confirmatory]phosphopantetheinyl transferase [Bacillus subtilis] [gi:10954339]
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15
[SID92309022]
A screen for compounds that inhibit liver stage malaria [AID624349, Type: other]
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16
[SID50112774]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_55, Type: Literature]
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17
[SID50112774]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_56, Type: Literature]
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18
[SID50112774]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_57, Type: Literature]
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19
[SID50112774]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_39, Type: Literature]
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20
[SID50112774]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_42, Type: Literature]
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