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SMR000060306 (CID 6362174) - Compound BioActivity Data
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BioActivity Outcomes:
Active(69)
 
 
Inactive(510)
 
 
Inconclusive(20)
 
 
Unspecified(9)
 
 
Top Targets:
7TM GPCR Srx(16)
 
 
 
7TM GPCR Srsx(13)
 
 
Death TRAILR..(12)
 
 
 
 
Tryp SPc(7)
 
 
alkPPc(6)
 
 
BioAssay Types:
Screening(407)
 
 
 
 
 
Confirmatory(181)
 
 
 
 
 
Literature(9)
 
 
BioActivity Types:
Potency(94)
 
 
 
 
 
IC50(26)
 
 
 
EC50(13)
 
 
 
AC50(3)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 550    Data Row: 608   Total Pages: 31   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103804940]
IC50 0.01High Throughput Screening Assay used to Identify Novel Compounds that Inhibit Mycobacterium Tuberculosis in 7H9 Media using Purified and Synthesized Compounds (2) [AID504556, Type: confirmatory]
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2
[SID103804940]
IC50 0.02A High Throughput Confirmatory Assay used to Identify Novel Compounds that Inhibit Mycobacterium Tuberculosis in the absence of Glycerol using Purified and Synthesized Compounds (2) [AID504564, Type: confirmatory]
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3
[SID3716413]
CC50 0.039A Cell Based Secondary Assay to Explore Cytotoxicity in HepG2 Cells of Compounds that Modulate Non-Replicating, Drug-tolerant Mycobacterium tuberculosis [AID489018, Type: confirmatory]
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4
[SID103804940]
CC50 0.098A Cell Based Secondary Assay to Explore Cytotoxicity in HepG2 Cells of Compounds that Modulate Mycobacterium tuberculosis in Media Containing Glycerol versus Media without Glycerol [AID504642, Type: confirmatory]
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5
[SID103804940]
CC50 0.1A Cell Based Secondary Assay to Explore Cytotoxicity in HepG2 Cells of Compounds that Modulate Mycobacterium tuberculosis in Media Containing Glycerol versus Media without Glycerol (2) [AID504682, Type: confirmatory]
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6
[SID3716413]
IC50 0.1A Cell Based Secondary Assay to Explore Compounds that Modulate Non-Replicating, Drug-tolerant Compounds in Replicating H37Rv TB of Mycobacterium tuberculosis [AID492952, Type: confirmatory]
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7
[SID3716413]
IC50 0.1Elucidation of physiology of non-replicating, drug-tolerant Mycobacterium tuberculosis [AID488890, Type: confirmatory]
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8
[SID3716413]
Potency 0.1458qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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9
[SID3716413]
CC50 0.148A Cell Based Secondary Assay to Explore Cytotoxicity in THP-1 Cells of Compounds that Modulate Non-Replicating, Drug-tolerant Mycobacterium tuberculosis [AID489025, Type: confirmatory]
View
10
[SID103804940]
IC50 0.16High Throughput Screening Assay used to Identify Novel Compounds that Inhibit Mycobacterium Tuberculosis in 7H9 Media using Purified and Synthesized Compounds (3) [AID504646, Type: confirmatory]
View
11
[SID103804940]
IC50 0.17A High Throughput Confirmatory Assay used to Identify Novel Compounds that Inhibit Mycobacterium Tuberculosis in the absence of Glycerol using Purified and Synthesized Compounds (3) [AID504645, Type: confirmatory]
View
12
[SID103804940]
CC50 0.2A Cell Based Secondary Assay to Explore Cytotoxicity in THP-1 Cells of Compounds that Modulate Mycobacterium tuberculosis in Media Containing Glycerol versus Media without Glycerol [AID504640, Type: confirmatory]
View
13
[SID103804940]
CC50 0.2A Cell Based Secondary Assay to Explore Cytotoxicity in THP-1 Cells of Compounds that Modulate Mycobacterium tuberculosis in Media Containing Glycerol versus Media without Glycerol (2) [AID504683, Type: confirmatory]
View
14
[SID103804940]
CC50 0.2A Cell Based Secondary Assay To Explore Vero Cell Cytotoxicity of Purified and Synthesized Compounds that Inhibit Mycobacterium Tuberculosis (3) [AID504684, Type: confirmatory]
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15
[SID103804940]
IC50 0.2A High Throughput Confirmatory Assay used to Identify Novel Compounds that Inhibit Mycobacterium Tuberculosis in the absence of Glycerol using Purified and Synthesized Compounds [AID493181, Type: confirmatory]
View
16
[SID103804940]
IC50 0.2High Throughput Screening Assay used to Identify Novel Compounds that Inhibit Mycobacterium Tuberculosis in 7H9 Media using Purified and Synthesized Compounds [AID493198, Type: confirmatory]
View
17
[SID3716413]
Potency 0.206qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
View
18
[SID3716413]
CC50 0.5A Cell Based Secondary Assay to Explore Cytotoxicity in Vero E6 Cells of Compounds that Modulate Non-Replicating, Drug-tolerant Mycobacterium tuberculosis [AID492998, Type: confirmatory]
View
19
[SID3716413]
EC50 0.687Luminescence Cell-Based/Microorganism Dose Confirmation HTS to Identify Inhibitors of T.Cruzi Replication. [AID2044, Type: confirmatory]
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20
[SID3716413]
AC50_uM 0.7954Luminescence Cell-Based Dose Retest to Confirm Inhibitors of Beta Cell Apoptosis [AID449756, Type: confirmatory]
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