Bookmark and Share
cyclopropane (CID 6351) - Compound BioActivity Data
.
BioActivity Outcomes:
Unspecified(22)
 
 
BioAssay Types:
Literature(22)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 22    Data Row: 22   Total Pages: 2   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID134456336]
In-vitro air to lung partition coefficients of the compound, logK(lung) (human/rat) [AID603950, Type: Literature]
View
2
[SID134456336]
In-vitro air to blood partition coefficients of the compound, logK(blood) (human/rat) [AID603951, Type: Literature]
View
3
[SID134456336]
In-vitro blood to lung partition coefficients of the compound, logP(lung) (human/rat) [AID603952, Type: Literature]
View
4
[SID134456336]
Moderate liver toxicity, defined via clinical-chemistry results: ALT or AST serum activity 6 times the normal upper limit (N) or alkaline phosphatase serum activity of 1.7 N. Value is number of references indexed. [column 'BIOL' in source] [AID1079931, Type: Literature]
View
5
[SID134456336]
Highest frequency of moderate liver toxicity observed during clinical trials, expressed as a percentage. [column '% BIOL' in source] [AID1079932, Type: Literature]
View
6
[SID134456336]
Acute liver toxicity defined via clinical observations and clear clinical-chemistry results: serum ALT or AST activity > 6 N or serum alkaline phosphatases activity > 1.7 N. This category includes cytolytic, choleostatic and mixed liver toxicity. Value is number of references indexed. [column 'AIGUE' in source] [AID1079933, Type: Literature]
View
7
[SID134456336]
Highest frequency of acute liver toxicity observed during clinical trials, expressed as a percentage. [column '% AIGUE' in source] [AID1079934, Type: Literature]
View
8
[SID134456336]
Cytolytic liver toxicity, either proven histopathologically or where the ratio of maximal ALT or AST activity above normal to that of Alkaline Phosphatase is > 5 (see ACUTE). Value is number of references indexed. [column 'CYTOL' in source] [AID1079935, Type: Literature]
View
9
[SID134456336]
Choleostatic liver toxicity, either proven histopathologically or where the ratio of maximal ALT or AST activity above normal to that of Alkaline Phosphatase is < 2 (see ACUTE). Value is number of references indexed. [column 'CHOLE' in source] [AID1079936, Type: Literature]
View
10
[SID134456336]
Severe hepatitis, defined as possibly life-threatening liver failure or through clinical observations. Value is number of references indexed. [column 'MASS' in source] [AID1079937, Type: Literature]
View
11
[SID134456336]
Chronic liver disease either proven histopathologically, or through a chonic elevation of serum amino-transferase activity after 6 months. Value is number of references indexed. [column 'CHRON' in source] [AID1079938, Type: Literature]
View
12
[SID134456336]
Cirrhosis, proven histopathologically. Value is number of references indexed. [column 'CIRRH' in source] [AID1079939, Type: Literature]
View
13
[SID134456336]
Granulomatous liver disease, proven histopathologically. Value is number of references indexed. [column 'GRAN' in source] [AID1079940, Type: Literature]
View
14
[SID134456336]
Liver damage due to vascular disease: peliosis hepatitis, hepatic veno-occlusive disease, Budd-Chiari syndrome. Value is number of references indexed. [column 'VASC' in source] [AID1079941, Type: Literature]
View
15
[SID134456336]
Steatosis, proven histopathologically. Value is number of references indexed. [column 'STEAT' in source] [AID1079942, Type: Literature]
View
16
[SID134456336]
Malignant tumor, proven histopathologically. Value is number of references indexed. [column 'T.MAL' in source] [AID1079943, Type: Literature]
View
17
[SID134456336]
Benign tumor, proven histopathologically. Value is number of references indexed. [column 'T.BEN' in source] [AID1079944, Type: Literature]
View
18
[SID134456336]
Animal toxicity known. [column 'TOXIC' in source] [AID1079945, Type: Literature]
View
19
[SID134456336]
Presence of at least one case with successful reintroduction. [column 'REINT' in source] [AID1079946, Type: Literature]
View
20
[SID134456336]
Comments (NB not yet translated). [column 'COMMENTAIRES' in source] [AID1079947, Type: Literature]
View