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bromoethane (CID 6332) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(6)
 
 
Inactive(232)
 
 
Inconclusive(14)
 
 
Unspecified(37)
 
 
Top Targets:
NR LBD PPAR(13)
 
 
 
NR LBD ER(9)
 
 
NR LBD AR(9)
 
 
 
NR LBD TR(7)
 
 
NR LBD VDR(6)
 
 
 
BioAssay Types:
Confirmatory(212)
 
 
 
Literature(39)
 
 
 
 
 
Summary(24)
 
 
BioActivity Types:
Potency(193)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 278    Data Row: 289   Total Pages: 6   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID48413329]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary SingleCellCall Results [AID1189, Type: other]
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2
[SID48413329]
DSSTox (CPDBAS) Carcinogenic Potency Database Salmonella Mutagenicity [AID1194, Type: other]
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3
[SID48413329]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary Mouse Bioassay Results [AID1199, Type: other]
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4
[SID48413329]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary MultiCellCall Results [AID1205, Type: other]
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5
[SID48413329]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary Rat Bioassay Results [AID1208, Type: other]
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6
[SID103408345]
Inhibition of recombinant human topoisomerase 1-mediated unwinding of supercoiled plasmid DNA assessed as DNA intercalation after 2 hrs by gel electrophoresis [AID657780, Type: Literature]DNA topoisomerase 1 [gi:12644118]
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7
[SID103408345]
Antibacterial activity against Mycobacterium smegmatis mc2 155 after 72 hrs by MTT assay [AID658437, Type: Literature]
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8
[SID103408345]
Inhibition of Multidrug resistance efflux pump in Mycobacterium smegmatis mc2 155 assessed as EtBr accumulation measuring relative fluorescence at half the MIC measured for 60 mins by spectrophotometry relative to control [AID658581, Type: Literature]
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9
[SID103408345]
Inhibition of Multidrug resistance efflux pump in Mycobacterium smegmatis mc2 155 assessed as inhibition of EtBr efflux measuring normalized fluorescence at half the MIC measured for 60 mins by spectrophotometry relative to control [AID658586, Type: Literature]
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10
[SID103408345]
Partition coefficient (logP) [AID19825, Type: Literature]
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11
[SID103408345]
Apparent binding constant to T4 coliphage DNA was evaluated by measuring the loss of ethidium fluorescence [AID208559, Type: Literature]
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12
[SID103408345]
Apparent binding constant to calf thymus DNA was evaluated by measuring the loss of ethidium fluorescence [AID220343, Type: Literature]
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13
[SID103408345]
Apparent binding constant to poly (dA.dT) DNA was evaluated by measuring the loss of ethidium fluorescence [AID225772, Type: Literature]
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14
[SID103408345]
Apparent binding constant to poly (dG.dC) DNA was evaluated by measuring the loss of ethidium fluorescence [AID225774, Type: Literature]
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15
[SID103408345]
Binding affinity to calf thymus DNA assessed as thermal stability in BPE buffer at 2 uM [AID304717, Type: Literature]
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16
[SID103408345]
Binding affinity to calf thymus dodecamer DNA assessed as thermal stability in cacodylate buffer at 12 uM [AID304718, Type: Literature]
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17
[SID103408345]
Binding affinity to calf thymus dodecamer DNA assessed as thermal stability in cacodylate buffer containing 0.1 M NaCl at 12 uM [AID304719, Type: Literature]
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18
[SID17390006]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838, Type: other]
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19
[SID103408345]
Antimicrobial activity against Staphylococcus aureus CB370 harboring rpoB H481Y mutant gene [AID531117, Type: Literature]
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20
[SID103408345]
Antimicrobial activity against Staphylococcus aureus CB1947 harboring rpoB R484H, L520 deficient gyrA, gyrA S48L, gyrA E88K, R236 duplicated parC, parCH103Y, parC S80Y, parC E84G mutant genes selected after CBR-2092 exposure for 20 days [AID531120, Type: Literature]
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21
[SID103408345]
Antimicrobial activity against Staphylococcus aureus CB814 harboring gyrA S48L and parC S80F mutant genes [AID531123, Type: Literature]
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22
[SID103408345]
Antimicrobial activity against Staphylococcus aureus CB1952 harboring rpoB S486L, gyrA S48L, gyrA E88Q, gyrA G532S, parC S80F, parC E84L mutant genes selected after CBR-2092 exposure for 21 days [AID531126, Type: Literature]
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23
[SID103408345]
Antimicrobial activity against Staphylococcus aureus CB815 harboring rpoB H481Y, gyrA S48L and parC S80F mutant genes [AID531129, Type: Literature]
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24
[SID103408345]
Antimicrobial activity against Staphylococcus aureus CB1953 harboring rpoB H481Y, gyrA S84L, gyrA V598I, parC S80F, parC R570H mutant genes selected after CBR-2092 exposure for 7 days [AID531132, Type: Literature]
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25
[SID103408345]
Antimicrobial activity against Staphylococcus aureus CB1954 harboring rpoB H481Y, gyrA S84L, K809 deficient gyrA, parC S80F, parC A523D mutant genes selected after CBR-2092 exposure for 7 days [AID531135, Type: Literature]
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26
[SID103408345]
Antimicrobial activity against Escherichia coli K-12 3-AG300 harboring AcrB-F628F mutant gene [AID571763, Type: Literature]
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27
[SID103408345]
Antimicrobial activity against Escherichia coli K-12 3-AG300 harboring acrB::rpsLneo mutant gene [AID571764, Type: Literature]
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28
[SID103408345]
Antimicrobial activity against Escherichia coli K-12 3-AG300 harboring AcrB-615-628MexB mutant gene [AID571765, Type: Literature]
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29
[SID103408345]
Antimicrobial activity against Escherichia coli K-12 3-AG300 harboring AcrB-615-628MexB-N616 mutant gene [AID571766, Type: Literature]
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30
[SID103408345]
Antimicrobial activity against Escherichia coli K-12 3-AG300 harboring AcrB-615-628MexB-M626I mutant gene [AID571767, Type: Literature]
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31
[SID103408345]
Antimicrobial activity against Escherichia coli K-12 3-AG300 harboring AcrB-I626M mutant gene [AID571768, Type: Literature]
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32
[SID103408345]
Antibacterial activity against Escherichia coli KAM32 harboring plasmid pUC18 by CLSI broth microdilution method [AID571882, Type: Literature]
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33
[SID103408345]
Antibacterial activity against Escherichia coli KAM32 harboring recombinant plasmid pVBS1 encoding Acinetobacter baumannii abeS gene by CLSI broth microdilution method [AID571884, Type: Literature]
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34
[SID103408345]
Antimicrobial activity against Escherichia coli K-12 3-AG300 harboring AcrB-G616N mutant gene [AID571925, Type: Literature]
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35
[SID103408345]
Antimicrobial activity against Escherichia coli K-12 3-AG300 harboring AcrB-N623S-Q624S mutant gene [AID571926, Type: Literature]
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36
[SID103408345]
Ratio of MIC for Escherichia coli K-12 3-AG300 harboring acrB::rpsLneo mutant gene to MIC for Escherichia coli K-12 3-AG300 [AID571927, Type: Literature]
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37
[SID103408345]
Antimicrobial activity against Escherichia coli K-12 3-AG300 harboring AcrB-615-628MexB-S623N mutant gene [AID571931, Type: Literature]
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38
[SID103408345]
Ratio of MIC for Escherichia coli KAM32 harboring plasmid pUC18 to MIC for Escherichia coli KAM32 harboring recombinant plasmid pVBS1 encoding Acinetobacter baumannii abeS gene [AID572058, Type: Literature]
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39
[SID103408345]
Antibacterial activity against Acinetobacter baumannii AC0037 by CLSI broth microdilution method [AID572059, Type: Literature]
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40
[SID103408345]
Antibacterial activity against abeS-deficient Acinetobacter baumannii AC0037 by CLSI broth microdilution method [AID572060, Type: Literature]
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41
[SID103408345]
Ratio of MIC for Acinetobacter baumannii AC0037 to MIC for abeS-deficient Acinetobacter baumannii AC0037 [AID572061, Type: Literature]
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42
[SID103408345]
Antibacterial activity against abeS sigma abeS-deficient Acinetobacter baumannii AC0037 by CLSI broth microdilution method [AID572062, Type: Literature]
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43
[SID103408345]
Antimicrobial activity against Staphylococcus aureus CB1884 [AID530917, Type: Literature]
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44
[SID144207553]
Potency-Replicate_1 1.1126qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway [AID743075, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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45
[SID17390006]
Potency 133.332qHTS assay for small molecule antagonists of the retinoid-related orphan receptor gamma (ROR-gamma) signaling pathway [AID651802, Type: confirmatory]Nuclear receptor ROR-gamma [gi:49066040]
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46
[SID17390006]
Potency qHTS assay for environmental chemicals that activate the Aryl hydrocarbon Receptor (AhR) signaling pathway [AID651777, Type: confirmatory]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
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47
[SID144207553]
AhR Potency (uM) qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway: Summary [AID743122, Type: summary]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
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48
[SID144207553]
Potency-Replicate_1 qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway [AID743085, Type: confirmatory]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
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49
[SID17390006]
Potency qHTS Assay for Inhibitors of the ERK Signaling Pathway using a Homogeneous Screening Assay [AID995, Type: confirmatory]mitogen-activated protein kinase 1 [Homo sapiens] [gi:66932916]
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50
[SID17390006]
qHTS Assay for Inhibitors of YjeE [AID605, Type: confirmatory]tRNA threonylcarbamoyladenosine biosynthesis protein TsaE [gi:84028058]
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