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Tryptophan (CID 6305) - Compound BioActivity Data
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BioActivity Outcomes:
Active(95)
 
 
Inactive(583)
 
 
Inconclusive(77)
 
 
Unspecified(87)
 
 
Top Targets:
7tm 4(20)
 
 
alpha CA I II..(18)
 
 
 
NR LBD PPAR(16)
 
 
 
NR LBD ER(15)
 
 
NR LBD AR(14)
 
 
BioAssay Types:
Confirmatory(427)
 
 
 
 
 
Literature(173)
 
 
 
 
Screening(133)
 
 
 
Summary(49)
 
 
 
 
BioActivity Types:
Potency(403)
 
 
 
 
 
IC50(40)
 
 
 
 
Kd(6)
 
 
EC50(6)
 
 
Ki(2)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 671    Data Row: 842   Total Pages: 43   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103241616]
Km 0.83Activity at Aspergillus fumigatus CdpNPT by HPLC analysis [AID422797, Type: Literature]
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2
[SID103241616]
IC50 3.5Antioxidant activity assessed as inhibition of HOCl-induced oxidation of DHR by rhodamine 123 staining [AID537676, Type: Literature]
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3
[SID46392975]
Kd 7.5Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain A, Regulatory Features Of The Trp Operon And The Crystal Structure Of The Trp Rna-Binding Attenuation Protein From Bacillus Stearothermophilus. [gi:4930086]
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4
[SID46392975]
Kd 7.5Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain A, Regulatory Features Of The Trp Operon And The Crystal Structure Of The Trp Rna-Binding Attenuation Protein From Bacillus Stearothermophilus. [gi:4930086]
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5
[SID46392975]
Kd 7.5Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain K, Regulatory Features Of The Trp Operon And The Crystal Structure Of The Trp Rna-Binding Attenuation Protein From Bacillus Stearothermophilus. [gi:4930096]
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6
[SID46392975]
Kd 7.5Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain K, Regulatory Features Of The Trp Operon And The Crystal Structure Of The Trp Rna-Binding Attenuation Protein From Bacillus Stearothermophilus. [gi:4930096]
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7
[SID90341602]
Potency 8.4368qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a [AID504332, Type: confirmatory]euchromatic histone-lysine N-methyltransferase 2 [Homo sapiens] [gi:168985070]
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8
[SID50107108]
Potency 11.2202qHTS for differential inhibitors of proliferation of Plasmodium falciparum line 7G8 [AID1815, Type: confirmatory]
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9
[SID103241616]
IC50 12.5892Antiplasmodial activity against Plasmodium falciparum 3D7 after 72 hrs by SYBR green assay [AID524790, Type: Literature]
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10
[SID103241616]
IC50 12.5892Antiplasmodial activity against Plasmodium falciparum 7G8 after 72 hrs by SYBR green assay [AID524791, Type: Literature]
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11
[SID103241616]
IC50 12.5892Antiplasmodial activity against Plasmodium falciparum HB3 after 72 hrs by SYBR green assay [AID524795, Type: Literature]
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12
[SID103241616]
IC50 12.5892Antiplasmodial activity against Plasmodium falciparum W2 after 72 hrs by SYBR green assay [AID524796, Type: Literature]
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13
[SID26732620]
Potency 14.1254qHTS Assay for the Inhibitors of Schistosoma Mansoni Peroxiredoxins [AID485364, Type: confirmatory]thioredoxin glutathione reductase [Schistosoma mansoni] [gi:15149312]
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14
[SID103241616]
IC50 19.2Antioxidant activity assessed as inhibition of peroxynitrite anion-induced oxidation of non-fluorescent DHR by rhodamine 123 staining in presence of NaHCO3 [AID537680, Type: Literature]
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15
[SID144208444]
AhR Potency (uM) 22.5614qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway: Summary [AID743122, Type: summary]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
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16
[SID46393776]
Kd 30Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain C, Structure Of Trprs Ii Bound To Atp [gi:73536118]
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17
[SID46393776]
Kd 30Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain C, Structure Of Trprs Ii Bound To Atp [gi:73536118]
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18
[SID144208444]
Potency-Replicate_1 30.669qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway [AID743085, Type: confirmatory]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
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19
[SID103241616]
IC50 31.9Antioxidant activity assessed as inhibition of peroxynitrite anion-induced oxidation of non-fluorescent DHR by rhodamine 123 staining in absence of NaHCO3 [AID537679, Type: Literature]
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20
[SID26732620]
Potency 50.1187qHTS Assay for Inhibitors of BAZ2B [AID504333, Type: confirmatory]bromodomain adjacent to zinc finger domain 2B [Homo sapiens] [gi:6683500]
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