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BioActivity Data for Compound Threonine (CID 6288)

BioActivity Outcomes:
Active(1)
 
 
Inactive(103)
 
 
Inconclusive(1)
 
 
Unspecified(5)
 
 
Top Targets:
NR LBD PPAR(8)
 
 
NR LBD AR(7)
 
 
NR LBD ER(7)
 
 
NR LBD Fxr(4)
 
 
NR LBD GR(4)
 
 
BioAssay Types:
Confirmatory(70)
 
 
 
Summary(24)
 
 
Screening(10)
 
 
Literature(6)
 
 
 
BioAssay Categories:
In vitro(1)
 
 
Biochemical(2)
 
 
 
Toxicity(6)
 
 
ADME(1)
 
 
Cell-based(9)
 
 
 
BioActivity Types:
Potency(85)
 
 
 
AC50(3)
 
 
Ki(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 110    Data Row: 110   Total Pages: 6   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103247439]
Induction of nitrogen-starved wild type sigma1278b yeast Gap1-mediated trehalose activation at 10 mM [AID500825, Type: Literature]
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2
[SID103247439]
Retardation factor of the compound in cyclohexylamine-water-methyl ethyl ketone-1-butanol at 1:2.5:5:5 ratio by paper chromatography [AID1149043, Type: Literature]
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3
[SID103247439]
Ki TP_TRANSPORTER: inhibition of L-tryptophan uptake in Xenopus laevis oocytes [AID681113, Type: Literature]Monocarboxylate transporter 10 [gi:81871541]
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4
[SID103247439]
Bitter threshold value; NB denotes 'Not bitter' [AID233320, Type: Literature]
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5
[SID103247439]
Compound was evaluated for the inhibition of Phenylalanine dehydrogenase of Sporosarcina species [AID157604, Type: Literature]
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6
[SID103247439]
Partition coefficient (logP) [AID26797, Type: Literature]
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7
[SID170465476]
Ac50 0.316228qHTS Assay for Identifying Compounds that block Entry of Ebola Virus: Screen 2, green channel [AID1117310, Type: confirmatory]
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8
[SID170465476]
Ac50 5.62341qHTS Assay for Identifying Compounds that block Entry of Ebola Virus: Screen2, ratio channel [AID1117312, Type: confirmatory]
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9
[SID170465476]
Ac50 6.30957qHTS Assay for Identifying Compounds that block Entry of Ebola Virus: Screen 2, blue channel [AID1117314, Type: confirmatory]
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10
[SID170465476]
nuclear beta catenin stimulation in WNT3A conditioned C2C12 cells-screen [AID1117326, Type: screening]
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11
[SID170465476]
insulin secretion from INS-1E cells in the presence of 5 mM glucose-screen [AID1117329, Type: screening]
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12
[SID170465476]
GSK3B-pretreated HCT116 viability from Cell TiterGlo-screen [AID1117336, Type: screening]
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13
[SID170465476]
VEGF stimulated ADSC/ECFC co-culture CD31-stained tube area decrease-screen [AID1117340, Type: screening]
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14
[SID170465476]
GLP1 secretion from NCI-H716 cells-screen [AID1117341, Type: screening]
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15
[SID170465476]
HCT116 viability from Cell TiterGlo-screen [AID1117342, Type: screening]
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16
[SID170465476]
SW480 viability from Cell TiterGlo-screen [AID1117343, Type: screening]
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17
[SID170465476]
DLD-1 viability from Cell TiterGlo-screen [AID1117346, Type: screening]
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18
[SID170465476]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the farnesoid-X-receptor (FXR) signaling pathway - cell viability counter screen [AID743221, Type: confirmatory]
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19
[SID144205707]
Potency qHTS for Inhibitors of binding or entry into cells for Marburg Virus [AID720532, Type: confirmatory]gene 4 small orf - Marburg virus [Marburg marburgvirus] [gi:420597]
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20
[SID170465476]
Potency-Replicate_1 qHTS assay for small molecule activators of the heat shock response signaling pathway [AID743210, Type: confirmatory]heat shock protein beta-1 [Homo sapiens] [gi:4504517]
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