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BioActivity Data for Compound Valine (CID 6287)

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BioActivity Outcomes:
Active(31)
 
 
Inactive(4)
 
 
Inconclusive(3)
 
 
Unspecified(17)
 
 
Top Targets:
MFS(5)
 
 
 
 
Arginase-like(3)
 
 
BioAssay Types:
Literature(55)
 
 
 
 
 
BioActivity Types:
Ki(3)
 
 
 
EC50(2)
 
 
 
IC50(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 54    Data Row: 55   Total Pages: 3   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID46393202]
Ki 3600Experimentally measured binding affinity data (Ki) for protein-ligand complexes derived from PDB [AID977610, Type: Literature]Chain A, Arginase-L-Valine Complex [gi:56553820]
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2
[SID46393202]
Ki 3600Experimentally measured binding affinity data (Ki) for protein-ligand complexes derived from PDB [AID977610, Type: Literature]Chain A, Arginase-L-Valine Complex [gi:56553820]
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3
[SID46393202]
Experimentally measured binding affinity data derived from PDB [AID1811, Type: Literature]Chain A, Arginase-L-Valine Complex [gi:56553820]
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4
[SID103224325]
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced TNFalpha secretion at 1.5 to 4.5 uM after 12 hrs by ELISA [AID722330, Type: Literature]
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5
[SID103224325]
Drug uptake in human RBC assessed as membrane localization at 9 uM after 10 to 30 mins by confocal microscopic analysis [AID722331, Type: Literature]
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6
[SID103224325]
Antifungal activity against Candida parapsilosis ATCC 22019 after 48 hrs by NCCLS microbroth dilution method [AID722318, Type: Literature]
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7
[SID103224325]
Antifungal activity against Cryptococcus neoformans after 72 hrs by NCCLS microbroth dilution method [AID722319, Type: Literature]
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8
[SID103224325]
Antifungal activity against Candida albicans after 48 hrs by NCCLS microbroth dilution method [AID722320, Type: Literature]
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9
[SID103224325]
Antibacterial activity against Klebsiella pneumoniae ATCC 27736 after 18 hrs by broth dilution method [AID722321, Type: Literature]
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10
[SID103224325]
Antibacterial activity against Pseudomonas aeruginosa ATCC BAA-427 after 18 hrs by broth dilution method [AID722322, Type: Literature]
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11
[SID103224325]
Antibacterial activity against methicillin-resistant Staphylococcus aureus after 18 hrs by broth dilution method [AID722323, Type: Literature]
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12
[SID103224325]
Bactericidal activity against Escherichia coli ATCC 10536 assessed as induction of membrane damage at 5 uM after 30 mins by propidium iodide staining-based flow cytometric analysis [AID722312, Type: Literature]
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13
[SID103224325]
Antibacterial activity against Escherichia coli ATCC 10536 after 18 hrs by broth dilution method [AID722324, Type: Literature]
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14
[SID103224325]
Antibacterial activity against Bacillus subtilis ATCC 6633 after 18 hrs by broth dilution method [AID722325, Type: Literature]
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15
[SID103224325]
Antibacterial activity against Staphylococcus epidermidis NRRL B-4268 after 18 hrs by broth dilution method [AID722326, Type: Literature]
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16
[SID103224325]
Antibacterial activity against Staphylococcus aureus ATCC 9144 after 18 hrs by broth dilution method [AID722327, Type: Literature]
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17
[SID103224325]
Drug uptake in Escherichia coli ATCC 10536 assessed as membrane localization at 3 uM after 30 mins by confocal microscopic analysis [AID722314, Type: Literature]
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18
[SID103224325]
Antifungal activity against Aspergillus fumigatus after 72 hrs by NCCLS microbroth dilution method [AID722315, Type: Literature]
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19
[SID103224325]
Antifungal activity against Trichophyton mentagrophytes after 96 hrs by NCCLS microbroth dilution method [AID722316, Type: Literature]
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20
[SID103224325]
Antifungal activity against Sporothrix schenckii after 72 hrs by NCCLS microbroth dilution method [AID722317, Type: Literature]
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