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Daunorubicin (CID 62770) - Compound BioActivity Data
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BioActivity Outcomes:
Active(481)
 
 
Inactive(581)
 
 
Inconclusive(139)
 
 
Unspecified(32)
 
 
Top Targets:
7TM GPCR Srx(23)
 
 
 
7TM GPCR Srsx(21)
 
 
 
NR LBD PPAR(19)
 
 
 
 
Tryp SPc(11)
 
 
alkPPc(10)
 
 
BioAssay Types:
Confirmatory(475)
 
 
 
 
 
Screening(452)
 
 
 
 
 
Literature(45)
 
 
 
 
 
Summary(24)
 
 
 
 
BioActivity Types:
Potency(358)
 
 
 
 
 
IC50(93)
 
 
 
 
 
EC50(14)
 
 
 
AC50(10)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 979    Data Row: 1233   Total Pages: 25   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103582698]
IC50 8.55e-07Cytotoxicity of compound was tested against Molt-4 cell line (T-cell leukemia) after incubation for 72 hour [AID125331, Type: other]
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2
[SID103582698]
IC50 0.001Cytotoxicity of compound was tested against Molt-4 cell line (T-cell leukemia) after incubation for 24 hour [AID125330, Type: other]
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3
[SID144208357]
Potency-Replicate_1 0.0024qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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4
[SID103582698]
IC50 0.003Growth Inhibition of P388/0 cell lines. [AID153384, Type: Literature]
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5
[SID85273781]
Potency 0.0058qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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6
[SID144208357]
Potency-Replicate_1 0.0123qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
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7
[SID103582698]
IC50 0.015Cytotoxicity against drug-sensitive K562 cell line by MTS assay [AID261111, Type: Literature]
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8
[SID103582698]
IC50 0.016Cytotoxic activity against L-1210 parental cell line [AID94727, Type: other]
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9
[SID85273781]
Potency 0.0206qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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10
[SID144208357]
Potency-Replicate_1 0.0218qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
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11
[SID85273781]
Potency 0.0731qHTS for induction of synthetic lethality in tumor cells producing 2HG: qHTS for the HT-1080-NT fibrosarcoma cell line [AID686970, Type: confirmatory]IDH1 [Homo sapiens] [gi:49168486]
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12
[SID103582698]
IC50 0.098Cytotoxicity of compound was tested against P-388 cell line (mouse leukemia) after incubation for 72 hour [AID152269, Type: other]
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13
[SID103582698]
IC50 0.098Cytotoxicity of compound was tested against HL-60 cell line (promyelocytic leukemia) after incubation for 24 hour [AID81459, Type: other]
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14
[SID103582698]
IC50 0.098Cytotoxicity of compound was tested against HL-60 cell line (promyelocytic leukemia) after incubation for 72 hour [AID81460, Type: other]
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15
[SID103582698]
IC50 0.098Cytotoxicity of compound was tested against HMEC cell line (human mamm epithelial cells) after incubation for 72 hour [AID83154, Type: other]
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16
[SID17389073]
Potency 0.1Cell Viability - LYMP2-022 [AID987, Type: confirmatory]
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17
[SID144208357]
Potency-Replicate_1 0.1227qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line [AID743042, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
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18
[SID17389073]
Potency 0.1259Cell Viability - LYMP2-024 [AID988, Type: confirmatory]
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19
[SID144208357]
AR Potency (uM) 0.132506qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line: Summary [AID743054, Type: summary]AR protein [Homo sapiens] [gi:124375976]
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20
[SID85273781]
Potency 0.1458qHTS for induction of synthetic lethality in tumor cells producing 2HG: qHTS for the HT-1080-IDH1KD cell line [AID686971, Type: confirmatory]
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21
[SID103582698]
IC50 0.147Cytotoxic activity against adriamycin (ADR) resistant L-1210 cell line [AID94728, Type: other]
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22
[SID144208357]
Potency-Replicate_1 0.1545qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway [AID743065, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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23
[SID85273781]
AbsAC35_uM 0.156HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Other_Dose_CherryPick_Activity_Set2 [AID743395, Type: confirmatory]
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24
[SID17389073]
Potency 0.1585Cell Viability - LYMP2-018 [AID985, Type: confirmatory]
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25
[SID17389073]
Potency 0.1585Cell Viability - LYMP2-012 [AID982, Type: confirmatory]
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26
[SID17389073]
Potency 0.1585Cell Viability - LYMP2-005 [AID967, Type: confirmatory]
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27
[SID855543]
IC50 0.1736Tumor Hsp90 Inhibitors Dose Response Confirmation [AID712, Type: confirmatory]heat shock protein HSP 90-alpha isoform 2 [Homo sapiens] [gi:154146191]
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28
[SID855543]
IC50 0.1736Tumor Hsp90 Inhibitors Dose Response Confirmation [AID712, Type: confirmatory]90-kda heat shock protein beta HSP90 beta [Homo sapiens] [gi:4261762]
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29
[SID103582698]
IC50 0.19Cytotoxicity of compound was tested against NHDF cell line (norm human dermal fibroblast) after incubation for 24 hour [AID143796, Type: other]
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30
[SID144208357]
Potency-Replicate_1 0.1945qHTS assay for small molecules that induce genotoxicity in human embryonic kidney cells expressing luciferase-tagged ATAD5 [AID651632, Type: confirmatory]ATPase family AAA domain-containing protein 5 [gi:296439460]
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31
[SID17389073]
Potency 0.1995Cell Viability - LYMP2-010 [AID981, Type: confirmatory]
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32
[SID144208357]
Potency-Replicate_1 0.2182qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway - cell viability counter screen [AID743064, Type: confirmatory]
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33
[SID103582698]
IC50 0.22Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay [AID379893, Type: Literature]
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34
[SID855543]
Potency 0.2311qHTS for inhibitors of binding or entry into cells for Marburg Virus [AID540276, Type: confirmatory]gene 4 small orf - Marburg virus [gi:420597]
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35
[SID85273781]
AC50_uM 0.235S100A4: HTS Measured in Biochemical System Using Plate Reader - 7045-01_Inhibitor_Dose_CherryPick_Activity [AID687001, Type: confirmatory]S100A4 [Homo sapiens] [gi:47496637]
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36
[SID103582698]
IC50 0.25Cytotoxicity against human MDA-MB-231 cells after 48 hrs by MTT assay [AID379894, Type: Literature]
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37
[SID17389073]
Potency 0.2512Cell Viability - LYMP2-009 [AID968, Type: confirmatory]
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38
[SID144208357]
Ratio Potency (uM) 0.261577qHTS assay to identify small molecule agonists of the glucocorticoid receptor (GR) signaling pathway: Summary [AID720719, Type: summary]glucocorticoid receptor [Homo sapiens] [gi:311348376]
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39
[SID144208357]
Ratio Potency (uM) 0.28353qHTS assay to identify small molecule agonists of the androgen receptor (AR) signaling pathway: Summary [AID743053, Type: summary]AR protein [Homo sapiens] [gi:124375976]
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40
[SID103582698]
IC50 0.287Cytotoxicity of compound was tested against Ovcar-3 cell line (ovarian carcinoma) after incubation for 72 hour [AID151510, Type: other]
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41
[SID103582698]
IC50 0.294Cytotoxicity of compound was tested against CHO cell line (Chinese hamster ovary) after incubation for 72 hour [AID44890, Type: other]
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42
[SID103582698]
ED50 0.3Dose required to inhibit the RNA synthesis in leukemia L1210 cells [AID97979, Type: Literature]
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43
[SID17389073]
Potency 0.3162Cell Viability - LYMP2-003 [AID965, Type: confirmatory]
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44
[SID103582698]
IC50 0.32Cytotoxicity against human HeLa cells after 48 hrs by MTT assay [AID379896, Type: Literature]
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45
[SID103582698]
ED50 0.33Inhibition of [3H]uridine incorporation into proliferating L1210 cells. [AID166707, Type: Literature]
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46
[SID144208357]
Potency-Replicate_1 0.3459qHTS assay for small molecule agonists of the p53 signaling pathway [AID651631, Type: confirmatory]Cellular tumor antigen p53 [gi:269849759]
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47
[SID103582698]
IC50 0.357Cytotoxicity of compound was tested against HT-29 cell line (colon carcinoma) after incubation for 72 hour [AID83593, Type: other]
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48
[SID855543]
Potency 0.3696Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation [AID504832, Type: confirmatory]
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49
[SID144208357]
ATAD5 Potency (uM) 0.379229qHTS assay for small molecules that induce genotoxicity in human embryonic kidney cells expressing luciferase-tagged ATAD5: Summary [AID720516, Type: summary]ATPase family AAA domain-containing protein 5 [gi:296439460]
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50
[SID103582698]
IC50 0.39Cytotoxicity of compound was tested against Ovcar-3 cell line (ovarian carcrnoma) after incubation for 24 hour [AID151511, Type: other]
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