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Daunorubicin (CID 62770) - Compound BioActivity Data
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BioActivity Outcomes:
Active(479)
 
 
Inactive(588)
 
 
Inconclusive(141)
 
 
Unspecified(32)
 
 
Top Targets:
7TM GPCR Srx(23)
 
 
 
7TM GPCR Srsx(21)
 
 
 
NR LBD PPAR(19)
 
 
 
 
Tryp SPc(11)
 
 
alkPPc(10)
 
 
BioAssay Types:
Confirmatory(509)
 
 
 
 
 
Screening(453)
 
 
 
 
 
Literature(52)
 
 
 
 
 
Summary(24)
 
 
 
 
BioActivity Types:
Potency(359)
 
 
 
 
 
IC50(93)
 
 
 
 
 
EC50(14)
 
 
 
AC50(10)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 979    Data Row: 1240   Total Pages: 62   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103582698]
IC50 8.55e-07Cytotoxicity of compound was tested against Molt-4 cell line (T-cell leukemia) after incubation for 72 hour [AID125331, Type: confirmatory]
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2
[SID103582698]
IC50 0.001Cytotoxicity of compound was tested against Molt-4 cell line (T-cell leukemia) after incubation for 24 hour [AID125330, Type: confirmatory]
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3
[SID144208357]
Potency-Replicate_1 0.0024qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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4
[SID103582698]
IC50 0.003Growth Inhibition of P388/0 cell lines. [AID153384, Type: Literature]
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5
[SID85273781]
Potency 0.0058qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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6
[SID144208357]
Potency-Replicate_1 0.0123qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
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7
[SID103582698]
IC50 0.015Cytotoxicity against drug-sensitive K562 cell line by MTS assay [AID261111, Type: Literature]
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8
[SID103582698]
IC50 0.016Cytotoxic activity against L-1210 parental cell line [AID94727, Type: confirmatory]
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9
[SID85273781]
Potency 0.0206qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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10
[SID144208357]
Potency-Replicate_1 0.0218qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
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11
[SID85273781]
Potency 0.0731qHTS for induction of synthetic lethality in tumor cells producing 2HG: qHTS for the HT-1080-NT fibrosarcoma cell line [AID686970, Type: confirmatory]IDH1 [Homo sapiens] [gi:49168486]
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12
[SID103582698]
IC50 0.098Cytotoxicity of compound was tested against HL-60 cell line (promyelocytic leukemia) after incubation for 24 hour [AID81459, Type: confirmatory]
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13
[SID103582698]
IC50 0.098Cytotoxicity of compound was tested against HL-60 cell line (promyelocytic leukemia) after incubation for 72 hour [AID81460, Type: confirmatory]
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14
[SID103582698]
IC50 0.098Cytotoxicity of compound was tested against HMEC cell line (human mamm epithelial cells) after incubation for 72 hour [AID83154, Type: confirmatory]
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15
[SID103582698]
IC50 0.098Cytotoxicity of compound was tested against P-388 cell line (mouse leukemia) after incubation for 72 hour [AID152269, Type: confirmatory]
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16
[SID17389073]
Potency 0.1Cell Viability - LYMP2-022 [AID987, Type: confirmatory]
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17
[SID144208357]
Potency-Replicate_1 0.1227qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line [AID743042, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
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18
[SID17389073]
Potency 0.1259Cell Viability - LYMP2-024 [AID988, Type: confirmatory]
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19
[SID144208357]
AR Potency (uM) 0.132506qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line: Summary [AID743054, Type: summary]AR protein [Homo sapiens] [gi:124375976]
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20
[SID85273781]
Potency 0.1458qHTS for induction of synthetic lethality in tumor cells producing 2HG: qHTS for the HT-1080-IDH1KD cell line [AID686971, Type: confirmatory]
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