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BioActivity Data for Compound Ornithine (CID 6262)

BioActivity Outcomes:
Active(10)
 
 
Inactive(7)
 
 
Unspecified(3)
 
 
Top Targets:
Amidinotransf(3)
 
 
Arginase-like(3)
 
 
PBP2 HisJ LAO(3)
 
 
PLPDE III ODC(1)
 
 
BioAssay Types:
Literature(11)
 
 
 
Screening(8)
 
 
 
Confirmatory(1)
 
 
BioActivity Types:
Ki(4)
 
 
Kd(3)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 14    Data Row: 20   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID46392411]
Kd 0.03Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain E, Structural Bases For Multiple Ligand Specificity Of The Periplasmic Lysine-, Arginine-, Ornithine-Binding Protein [gi:1065315]
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2
[SID46392411]
Kd 0.03Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain E, Structural Bases For Multiple Ligand Specificity Of The Periplasmic Lysine-, Arginine-, Ornithine-Binding Protein [gi:1065315]
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3
[SID46394355]
Ki 253Experimentally measured binding affinity data (Ki) for protein-ligand complexes derived from PDB [AID977610, Type: Literature]Chain A, Crystal Structure And Mechanism Of L-Arginine: Glycine Amidinotransferase: A Mitochondrial Enzyme Involved In Creatine Biosynthesis [gi:157836830]
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4
[SID46394355]
Ki 253Experimentally measured binding affinity data (Ki) for protein-ligand complexes derived from PDB [AID977610, Type: Literature]Chain A, Crystal Structure And Mechanism Of L-Arginine: Glycine Amidinotransferase: A Mitochondrial Enzyme Involved In Creatine Biosynthesis [gi:157836830]
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5
[SID46392150]
Ki 1000Experimentally measured binding affinity data (Ki) for protein-ligand complexes derived from PDB [AID977610, Type: Literature]Chain A, Crystal Structure Of The H141c Arginase Variant Complexed With Products Ornithine And Urea [gi:13786702]
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6
[SID46392150]
Ki 1000Experimentally measured binding affinity data (Ki) for protein-ligand complexes derived from PDB [AID977610, Type: Literature]Chain A, Crystal Structure Of The H141c Arginase Variant Complexed With Products Ornithine And Urea [gi:13786702]
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7
[SID46394355]
Experimentally measured binding affinity data derived from PDB [AID1811, Type: Literature]Chain A, Crystal Structure And Mechanism Of L-Arginine: Glycine Amidinotransferase: A Mitochondrial Enzyme Involved In Creatine Biosynthesis [gi:157836830]
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8
[SID225144364]
SW480 viability from Cell TiterGlo-screen [AID1117343, Type: screening]
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9
[SID46392150]
Experimentally measured binding affinity data derived from PDB [AID1811, Type: Literature]Chain A, Crystal Structure Of The H141c Arginase Variant Complexed With Products Ornithine And Urea [gi:13786702]
View
10
[SID46392411]
Experimentally measured binding affinity data derived from PDB [AID1811, Type: Literature]Chain E, Structural Bases For Multiple Ligand Specificity Of The Periplasmic Lysine-, Arginine-, Ornithine-Binding Protein [gi:1065315]
View
11
[SID103241659]
Kd 250Binding affinity to ODC (unknown origin) [AID1094409, Type: confirmatory]Ornithine decarboxylase [gi:118377]
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12
[SID103241659]
Partition coefficient (logP) [AID26797, Type: Literature]
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13
[SID103241659]
Bitter threshold value; NB denotes 'Not bitter' [AID233320, Type: Literature]
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14
[SID225144364]
nuclear beta catenin stimulation in WNT3A conditioned C2C12 cells-screen [AID1117326, Type: screening]
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15
[SID225144364]
insulin secretion from INS-1E cells in the presence of 5 mM glucose-screen [AID1117329, Type: screening]
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16
[SID225144364]
GSK3B-pretreated HCT116 viability from Cell TiterGlo-screen [AID1117336, Type: screening]
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17
[SID225144364]
VEGF stimulated ADSC/ECFC co-culture CD31-stained tube area decrease-screen [AID1117340, Type: screening]
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18
[SID225144364]
GLP1 secretion from NCI-H716 cells-screen [AID1117341, Type: screening]
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19
[SID225144364]
HCT116 viability from Cell TiterGlo-screen [AID1117342, Type: screening]
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20
[SID225144364]
DLD-1 viability from Cell TiterGlo-screen [AID1117346, Type: screening]
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