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BioActivity Data for Compound Mannitol (CID 6251)

BioActivity Outcomes:
Active(2)
 
 
Inactive(862)
 
 
Inconclusive(37)
 
 
Unspecified(360)
 
 
Top Targets:
7tm 4(68)
 
 
 
NR LBD PPAR(29)
 
 
NR LBD ER(25)
 
 
 
 
NR LBD AR(24)
 
 
 
 
NR LBD VDR(16)
 
 
BioAssay Types:
Confirmatory(483)
 
 
 
 
Screening(355)
 
 
 
Literature(212)
 
 
 
 
Summary(72)
 
 
 
BioActivity Types:
Potency(403)
 
 
 
 
IC50(150)
 
 
 
 
AC50(3)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 959    Data Row: 1261   Total Pages: 64   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID56322640]
Inhibitors of Epstein-Barr LMP1 inducible NF-kappaB luciferase reporter Measured in Cell-Based System Using Plate Reader - 2122-01_Inhibitor_SinglePoint_HTS_Activity [AID504558, Type: screening]LMP1 [Human herpesvirus 4] [gi:23893668]
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2
[SID48416194]
DSSTox (FDAMDD) FDA Maximum (Recommended) Daily Dose Database [AID1195, Type: other]
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3
[SID103191605]
IC50 30Antioxidant activity assessed as DPPH radical scavenging activity after 30 mins [AID377830, Type: Literature]
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4
[SID103191605]
IC50 30Antioxidant activity assessed as authentic peroxynitrite free radical scavenging activity after 30 mins [AID377831, Type: Literature]
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5
[SID103191605]
IC50 30Antioxidant activity assessed as 3-morpholinosydnonimine-derived peroxynitrite free radical scavenging activity after 30 mins [AID377832, Type: Literature]
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6
[SID103191605]
IC50 9600Antioxidant activity at pH 7.4 by hydroxyl radical scavenging assay [AID386915, Type: Literature]
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7
[SID103191605]
IC50 13800Hydroxyl radical scavenging activity by chemiluminescence technique in mouse thymus cells [AID114585, Type: Literature]
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8
[SID103191605]
Binding to POPC (palmitoyl-oleolyl-phosphatidyl-choline) liposomes using biosensor system [AID156202, Type: Literature]
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9
[SID103191605]
Binding to POPC/GMI liposomes using biosensor system [AID156204, Type: Literature]
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10
[SID103191605]
Partition coefficient (logP) [AID26811, Type: Literature]
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11
[SID103191605]
Apparent permeability coefficient (Papp) (Caco-2 cell monolayer) [AID28392, Type: Literature]
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12
[SID103191605]
Cellular permeability (Pc) (Caco-2 cell monolayer) [AID28399, Type: Literature]
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13
[SID103191605]
Basolateral to apical fluxes across Caco-2 cell monolayers at 37 degree celsius was studied. [AID28406, Type: Literature]
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14
[SID103191605]
Fraction absorbed after oral administration in humans [AID29844, Type: Literature]
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15
[SID103191605]
Estimation of fraction absorbed (Fa) in the human intestine using biosensor technology. [AID29845, Type: Literature]
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16
[SID103191605]
Percent recovery of 500 ug/mL compound after administration in cirrhotic patients [AID7977, Type: Literature]
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17
[SID103191605]
Tested for effective permeability across the rat intestinal membrane using mass balance analysis [AID13452, Type: other]
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18
[SID103191605]
Percent of the drug absorbed after administration to humans was determined [AID15120, Type: Literature]
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19
[SID103191605]
Percent of drug absorbed by human intestine after oral administration [AID18847, Type: Literature]
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20
[SID103191605]
Aqueous solubility [AID19262, Type: Literature]
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