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lactofen (CID 62276) - Compound BioActivity Data
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BioActivity Outcomes:
Active(25)
 
 
Inactive(130)
 
 
Inconclusive(57)
 
 
Unspecified(2)
 
 
Top Targets:
NR LBD PPAR(21)
 
 
 
 
NR LBD AR(16)
 
 
 
 
NR LBD ER(16)
 
 
 
 
NR LBD Fxr(10)
 
 
 
 
NR LBD VDR(10)
 
 
 
BioAssay Types:
Confirmatory(155)
 
 
 
 
Summary(48)
 
 
 
 
Literature(2)
 
 
 
BioActivity Types:
Potency(191)
 
 
 
 
IC50(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 120    Data Row: 214   Total Pages: 11   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID123095259]
MIC50 16Antiparasitic activity against Toxoplasma gondii infected in HFF after 24 hrs by [3H]uracil incorporation assay [AID509521, Type: Literature]
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2
[SID144208498]
Ratio Potency (uM) 17.2889qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway: Summary [AID743063, Type: summary]AR protein [Homo sapiens] [gi:124375976]
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3
[SID144208498]
Potency-Replicate_1 17.2889qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway [AID743035, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
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4
[SID144208498]
Potency-Replicate_1 21.5797qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
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5
[SID144211185]
Potency-Replicate_1 21.6899qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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6
[SID144211185]
Potency-Replicate_1 24.3365qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
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7
[SID144211185]
Ratio Potency (uM) 24.5412qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway: Summary [AID743063, Type: summary]AR protein [Homo sapiens] [gi:124375976]
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8
[SID144211185]
Potency-Replicate_1 27.306qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
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9
[SID26757876]
Potency 31.6228qHTS assay for small molecule antagonists of androgen receptor signaling [AID588516, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
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10
[SID144211185]
Potency-Replicate_1 34.6654qHTS assay to identify small molecule antagonists of the farnesoid-X-receptor (FXR) signaling pathway [AID743217, Type: confirmatory]farnesoid X nuclear receptor [Homo sapiens] [gi:325495553]
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11
[SID26757876]
Potency 35.4813qHTS assay for small molecule agonists of the peroxisome proliferator-activated receptor alpha (PPARalpha) signaling pathway [AID651778, Type: confirmatory]Peroxisome proliferator-activated receptor alpha [gi:3041727]
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12
[SID144208498]
Ratio Potency (uM) 35.5396qHTS assay for small molecule disruptors of the mitochondrial membrane potential: Summary [AID720637, Type: summary]
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13
[SID144208498]
Potency-Replicate_1 48.3109qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line [AID743080, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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14
[SID144208498]
ER Potency (uM) 54.2058qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line: Summary [AID743091, Type: summary]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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15
[SID144208498]
TR Potency (uM) 60.8199qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway: Summary [AID743067, Type: summary]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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16
[SID144211185]
Potency-Replicate_1 61.1306qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
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17
[SID26757876]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_6, Type: other]
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18
[SID26757876]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_7, Type: other]
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19
[SID26757876]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_1, Type: other]
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20
[SID26757876]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_2, Type: other]
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