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bromoacetate (CID 6227) - Compound BioActivity Data
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BioActivity Outcomes:
Inactive(238)
 
 
Inconclusive(10)
 
 
Unspecified(16)
 
 
Top Targets:
NR LBD PPAR(13)
 
 
 
NR LBD ER(9)
 
 
NR LBD AR(9)
 
 
NR LBD TR(7)
 
 
NR LBD VDR(6)
 
 
BioAssay Types:
Confirmatory(212)
 
 
 
Summary(24)
 
 
 
Literature(17)
 
 
 
BioActivity Types:
Potency(194)
 
 
 
Ki(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 250    Data Row: 264   Total Pages: 14   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103246073]
Ki 77000Dissociation constant towards Protein-tyrosine phosphatase 1B receptor-inhibitor complex was determined using PNP as substrate [AID165176, Type: Literature]
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2
[SID103246073]
Ratio between dissociation constant and First-order rate constant (Ki / K inact) was determined [AID227010, Type: Literature]
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3
[SID103246073]
Mutagenic activity in Salmonella Typhimurium TA100 assessed as logarithm of his+ revertant number increasing activity by amens test [AID384212, Type: Literature]
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4
[SID103246073]
Dissociation constant, pKa of the compound [AID448096, Type: Literature]
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5
[SID17389676]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838, Type: other]
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6
[SID103246073]
The compound was tested for the ability to inactivate horse liver alcohol dehydrogenase in the absence of NAD+k [AID33714, Type: Literature]Alcohol dehydrogenase E chain [gi:113397]
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7
[SID103246073]
The compound was tested for the ability to inactivate horse liver alcohol dehydrogenase in the presence of 1 mM NAD+k [AID33719, Type: Literature]Alcohol dehydrogenase E chain [gi:113397]
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8
[SID103246073]
The compound was tested for the ability to inactivate horse liver alcohol dehydrogenase in the absence of NAD+k [AID33714, Type: Literature]Alcohol dehydrogenase S chain [gi:113406]
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9
[SID103246073]
The compound was tested for the ability to inactivate horse liver alcohol dehydrogenase in the presence of 1 mM NAD+k [AID33719, Type: Literature]Alcohol dehydrogenase S chain [gi:113406]
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10
[SID103246073]
Partition coefficient (logP) [AID23443, Type: Literature]
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11
[SID103246073]
The compound was tested for the ability to inactivate human liver alcohol dehydrogenase in the absence of NAD+K [AID33866, Type: Literature]
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12
[SID103246073]
The compound was tested for the ability to inactivate mouse liver alcohol dehydrogenase in the absence of NAD+K [AID33871, Type: Literature]
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13
[SID103246073]
The compound was tested for the ability to inactivate mouse liver alcohol dehydrogenase in the presence of 1 mM NAD+K; Slow inactivation [AID33873, Type: Literature]
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14
[SID103246073]
The compound was tested for the ability to inactivate rat liver alcohol dehydrogenase in the absence of NAD+K [AID33878, Type: Literature]
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15
[SID103246073]
The compound was tested for the ability to inactivate rat liver alcohol dehydrogenase in the presence of 1 mM NAD+K [AID33879, Type: Literature]
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16
[SID103246073]
First-order rate constant (K inact) for conversion of the ExI complex (Protein-tyrosine phosphatase 1B -inhibitor complex) into the covalent adduct, EI was determined using PNP as substrate [AID165175, Type: Literature]
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17
[SID144207855]
Potency-Replicate_1 0.1871qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway [AID743075, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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18
[SID17389676]
Potency 5.0119qHTS Assay for Agonists of the Thyroid Stimulating Hormone Receptor: Activators of Intracellular cAMP Concentrations in Parental HEK 293 [AID938, Type: confirmatory]thyroid stimulating hormone receptor [Homo sapiens] [gi:38016895]
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19
[SID17389676]
Potency qHTS Assay for Identifying the Cell-Membrane Permeable IMPase Inhibitors: Potentiation with Lithium [AID1457, Type: confirmatory]Inositol monophosphatase [gi:44888968]
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20
[SID17389676]
Potency qHTS assay for small molecule antagonists of the retinoid-related orphan receptor gamma (ROR-gamma) signaling pathway [AID651802, Type: confirmatory]Nuclear receptor ROR-gamma [gi:49066040]
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