Cytidine Triphosphate (CID 6176) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(5)
 
 
Unspecified(2)
 
 
Top Targets:
CTGs(1)
 
 
G1P cytidylyl..(1)
 
 
BioAssay Types:
Literature(7)
 
 
 
BioActivity Types:
IC50(1)
 
 
SAR
Target summary
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 6    Data Row: 7   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103511679]
Km 2.7Activity of HCV NS5B RNA polymerase S282T assessed as incorporation of 32P-UMP into RNA [AID278952, Type: Literature]
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2
[SID103511679]
Km 13.7Activity of HCV NS5B RNA polymerase assessed as incorporation of 32P-UMP into RNA [AID278951, Type: Literature]
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3
[SID103511679]
IC50 Inhibition of RNA synthesis activity of HSV 1b Con1 NS5B polymerase [AID386066, Type: Literature]
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4
[SID46393514]
 Experimentally measured binding affinity data derived from PDB [AID1811, Type: Literature]Chain A, Alpha-D-Glucose-1-Phosphate Cytidylyltransferase Complexed With Ctp [gi:60593932]
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5
[SID46393790]
 Experimentally measured binding affinity data derived from PDB [AID1811, Type: Literature]Chain A, Mechanisms Of Feedback Regulation And Drug Resistance Of Ctp Synthetases: Structure Of The [gi:82407748]
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6
[SID103511679]
 Ratio of Kcat to Km for HCV NS5B RNA polymerase [AID278942, Type: Literature]
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7
[SID103511679]
 Ratio of Kcat to Km for HCV NS5B RNA polymerase S282T mutant [AID278943, Type: Literature]
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