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Phenylalanine (CID 6140) - Compound BioActivity Data
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BioActivity Outcomes:
Active(82)
 
 
Inactive(260)
 
 
Inconclusive(7)
 
 
Unspecified(76)
 
 
Top Targets:
alpha CA I II..(31)
 
 
 
p450(11)
 
 
NR LBD TR(6)
 
 
 
HSD10-like SD..(6)
 
 
Bromo ALL-1(5)
 
 
BioAssay Types:
Literature(213)
 
 
 
 
Confirmatory(183)
 
 
 
 
Screening(4)
 
 
BioActivity Types:
Potency(155)
 
 
 
 
Ki(5)
 
 
 
IC50(3)
 
 
Kd(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 306    Data Row: 425   Total Pages: 22   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID46393329]
Kd 0.18Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain C, L-Leucine-Binding Protein With Phenylalanine Bound [gi:413915680]
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2
[SID103241518]
Ki 0.98Displacement of [3H]L-leucine from alpha-2delta containing calcium channel in murine brain [AID261154, Type: Literature]Voltage-dependent calcium channel subunit alpha-2/delta-1 [gi:46576352]
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3
[SID26753740]
Potency 11.2202qHTS assay for small molecule agonists of estrogen receptor alpha signaling [AID588514, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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4
[SID124877010]
Potency 54.4827qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway [AID651741, Type: confirmatory]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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5
[SID46391851]
Ki 12700Experimentally measured binding affinity data (Ki) for protein-ligand complexes derived from PDB [AID977610, Type: Literature]Chain A, Crystal Structure Of The Streptomyces Griseus Aminopeptidase Complexed With L-Phenylalanine [gi:15826677]
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6
[SID46391851]
Ki 12700Experimentally measured binding affinity data (Ki) for protein-ligand complexes derived from PDB [AID977610, Type: Literature]Chain A, Crystal Structure Of The Streptomyces Griseus Aminopeptidase Complexed With L-Phenylalanine [gi:15826677]
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7
[SID103241518]
Activation of of human recombinant CA14 by CO2 hydrase assay [AID291067, Type: Literature]Carbonic anhydrase 14 [gi:8928036]
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8
[SID103241518]
Activation of human recombinant carbonic anhydrase 5B by stopped-flow CO2 hydrase method [AID305777, Type: Literature]Carbonic anhydrase 5B, mitochondrial [gi:8928041]
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9
[SID103241518]
Activation of membrane associated mouse recombinant carbonic anhydrase 15 isoform by stopped-flow CO2 hydrase method [AID375787, Type: Literature]Carbonic anhydrase 15 [gi:30580362]
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10
[SID103241518]
Activation of mouse recombinant CA13 by CO2 hydrase method [AID268622, Type: Literature]Carbonic anhydrase 13 [gi:30580372]
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11
[SID103241518]
Activation of human recombinant carbonic anhydrase 5A by stopped-flow CO2 hydrase method [AID305776, Type: Literature]Carbonic anhydrase 5A, mitochondrial [gi:461680]
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12
[SID103241518]
Activation of human recombinant CA7 by CO2 hydrase assay [AID291065, Type: Literature]Carbonic anhydrase 7 [gi:1168744]
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13
[SID103241518]
Activation of human recombinant CA12 catalytic domain by stopped-flow CO2 hydration method [AID318346, Type: Literature]Carbonic anhydrase 12 [gi:5915866]
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14
[SID103241518]
Drug uptake in Escherichia coli ATCC 10536 assessed as membrane localization at 3 uM after 30 mins by confocal microscopic analysis [AID722314, Type: Literature]
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15
[SID103241518]
Antifungal activity against Aspergillus fumigatus after 72 hrs by NCCLS microbroth dilution method [AID722315, Type: Literature]
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16
[SID103241518]
Antifungal activity against Trichophyton mentagrophytes after 96 hrs by NCCLS microbroth dilution method [AID722316, Type: Literature]
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17
[SID103241518]
Antifungal activity against Sporothrix schenckii after 72 hrs by NCCLS microbroth dilution method [AID722317, Type: Literature]
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18
[SID103241518]
Antifungal activity against Candida parapsilosis ATCC 22019 after 48 hrs by NCCLS microbroth dilution method [AID722318, Type: Literature]
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19
[SID103241518]
Antifungal activity against Cryptococcus neoformans after 72 hrs by NCCLS microbroth dilution method [AID722319, Type: Literature]
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20
[SID103241518]
Antifungal activity against Candida albicans after 48 hrs by NCCLS microbroth dilution method [AID722320, Type: Literature]
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